KEGG   REACTION: R04037
Entry
R04037                      Reaction                               
Name
1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase
Definition
Phosphoribosyl-AMP + H2O <=> 5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide
Equation
C02741 + C00001 <=> C04896
Reaction class
RC01055  C02741_C04896
Enzyme
3.5.4.19
Pathway
rn00340  Histidine metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01230  Biosynthesis of amino acids
Module
M00026  Histidine biosynthesis, PRPP => histidine
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.19
     R04037  Phosphoribosyl-AMP + H2O <=> 5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide
Orthology
K01496  phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
K11755  phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31]
K14152  phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23]
Other DBs
RHEA: 20052
LinkDB

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