KEGG   REACTION: R04125
Entry
R04125                      Reaction                               
Name
[protein]-S8-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming)
Definition
[Protein]-S8-aminomethyldihydrolipoyllysine + Tetrahydrofolate <=> Dihydrolipoylprotein + 5,10-Methylenetetrahydrofolate + Ammonia
Equation
C01242 + C00101 <=> C02972 + C00143 + C00014
Comment
a part step of glycine cleavage system (see R01221, R03425+R04125+R03815)
Reaction class
RC00022  C00101_C00143
RC00069  C01242_C02972
Enzyme
2.1.2.10
Pathway
rn00260  Glycine, serine and threonine metabolism
rn00670  One carbon pool by folate
rn00785  Lipoic acid metabolism
rn01100  Metabolic pathways
rn01200  Carbon metabolism
Module
M00621  Glycine cleavage system
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.10
     R04125  [Protein]-S8-aminomethyldihydrolipoyllysine + Tetrahydrofolate <=> Dihydrolipoylprotein + 5,10-Methylenetetrahydrofolate + Ammonia
Orthology
K00605  glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
Other DBs
RHEA: 16948
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