KEGG   REACTION: R05189
Entry
R05189                      Reaction                               
Name
acyl-CoA:methylmalonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing)
Definition
Acyl-CoA + n Methylmalonyl-CoA + 2n NADPH + 2n H+ + Acyl-carrier protein <=> Multi-methyl-branched acyl-[acp] + (n+1) CoA + n CO2 + 2n NADP+ + n H2O
Equation
C00040 + n C02557 + 2n C00005 + 2n C00080 + C00229 <=> C21392 + (n+1) C00010 + n C00011 + 2n C00006 + n C00001
Comment
Acy-carrier protein is acp domain of the enzyme itself.
mycocerosyl-[acp]-forming (ec 2.3.1.111, see R11450)
mycolipanoyl-[acp]-forming (ec 2.3.1.252, see R11451)
Enzyme
2.3.1.111       2.3.1.252
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.111
     R05189  Acyl-CoA + n Methylmalonyl-CoA + 2n NADPH + 2n H+ + Acyl-carrier protein <=> Multi-methyl-branched acyl-[acp] + (n+1) CoA + n CO2 + 2n NADP+ + n H2O
    2.3.1.252
     R05189  Acyl-CoA + n Methylmalonyl-CoA + 2n NADPH + 2n H+ + Acyl-carrier protein <=> Multi-methyl-branched acyl-[acp] + (n+1) CoA + n CO2 + 2n NADP+ + n H2O
Orthology
K11628  mycocerosic acid synthase [EC:2.3.1.111]
K12432  mycolipanoate synthase [EC:2.3.1.252]
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