KEGG   REACTION: R05621
Entry
R05621                      Reaction                               
Definition
Benzoate + NADH + H+ + Oxygen <=> (1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+
Equation
C00180 + C00004 + C00080 + C00007 <=> C06321 + C00003
Comment
BenA,BenB,BenC
Reaction class
RC00001  C00003_C00004
RC00270  C00180_C06321
Enzyme
1.14.12.10
Pathway
rn00362  Benzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00551  Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
    1.14.12.10
     R05621  Benzoate + NADH + H+ + Oxygen <=> (1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.12.10
   R07188  1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate
    R05621  (1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate
Orthology
K05549  benzoate/toluate 1,2-dioxygenase subunit alpha [EC:1.14.12.10 1.14.12.-]
K05550  benzoate/toluate 1,2-dioxygenase subunit beta [EC:1.14.12.10 1.14.12.-]
K05784  benzoate/toluate 1,2-dioxygenase reductase component [EC:1.18.1.-]
Other DBs
RHEA: 12636
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