KEGG   REACTION: R05881
Entry
R05881                      Reaction                               
Definition
Norajmaline + S-Adenosyl-L-methionine <=> Ajmaline + S-Adenosyl-L-homocysteine
Equation
Comment
norajmaline N-methyltransferase
Reaction class
RC00003  C00019_C00021
RC00113  C06542_C11810
Enzyme
2.1.1.-
Pathway
rn00901  Indole alkaloid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.-
     R05881  Norajmaline + S-Adenosyl-L-methionine <=> Ajmaline + S-Adenosyl-L-homocysteine
Orthology
K27779  norajmaline N-methyltransferase [EC:2.1.1.-]
Reference
1  [PMID:38212296]
  Authors
Guo J, Gao D, Lian J, Qu Y
  Title
De novo biosynthesis of antiarrhythmic alkaloid ajmaline.
  Journal
Nat Commun 15:457 (2024)
DOI:10.1038/s41467-024-44797-z
LinkDB

DBGET integrated database retrieval system