| Entry |
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| Name |
|
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| Formula |
C20H26N2O2
|
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| Exact mass |
326.1994
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| Mol weight |
326.43
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| Structure |
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| Remark |
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| Reaction |
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| Pathway |
| map01110 | Biosynthesis of secondary metabolites |
|
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| Module |
| M00979 | Ajmaline biosynthesis, geissoschizine => ajmaline |
|
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| Enzyme |
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| Brite |
Phytochemical compounds [BR:br08003]
Alkaloids
Alkaloids derived from tryptophan and anthranilic acid
Indole alkaloids
C06542 Ajmaline
Secondary metabolites in pathway maps [br08011.html]
Biosynthetic pathways and modules of secondary metabolites
C06542
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01B ANTIARRHYTHMICS, CLASS I AND III
C01BA Antiarrhythmics, class Ia
C01BA05 Ajmaline
D00199 Ajmaline (JP18)
Drug groups [BR:br08330]
Cardiovascular agent
DG01653 Antiarrhythmics
DG01652 Class I antiarrhythmic agent
DG01649 Class Ia antiarrhythmic agent
D00199 Ajmaline
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
D00199 Ajmaline
Target-based classification of drugs [BR:br08310]
Ion channels
Voltage-gated ion channels
Sodium channels
SCN1A
D00199 Ajmaline (JP18)
SCN2A
D00199 Ajmaline (JP18)
SCN3A
D00199 Ajmaline (JP18)
SCN4A
D00199 Ajmaline (JP18)
SCN5A
D00199 Ajmaline (JP18)
SCN8A
D00199 Ajmaline (JP18)
SCN9A
D00199 Ajmaline (JP18)
SCN10A
D00199 Ajmaline (JP18)
SCN11A
D00199 Ajmaline (JP18)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00199 Ajmaline
D00199 Ajmaline tablets
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00199
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 24
1 C8x C 13.1600 -15.7500
2 C8x C 13.1600 -17.1500
3 C8x C 14.3724 -17.8500
4 C8y C 15.5849 -17.1500
5 C8y C 15.5849 -15.7500
6 C8x C 14.3724 -15.0500
7 N1y N 16.7973 -17.8500
8 C1y C 18.0097 -17.1500
9 C1z C 18.0097 -15.7500
10 C1a C 16.7973 -19.2500
11 C1y C 19.2222 -17.8500
12 N1y N 20.4346 -17.1500
13 C1y C 20.4346 -15.7500
14 C1x C 19.2222 -15.0500
15 C1x C 19.2222 -19.2500
16 C1y C 20.5746 -18.5500
17 C1y C 21.6470 -19.2500
18 C1y C 21.6470 -17.8500
19 C1b C 22.8466 -19.9427
20 C1a C 24.0359 -19.2560
21 O1a O 22.8466 -17.1573
22 C1y C 21.9869 -14.4677
23 C1y C 18.1497 -13.1600
24 O1a O 17.3599 -11.9908
BOND 29
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 5 1 #Down
11 7 10 1
12 8 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 9 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 17 18 1
21 12 18 1
22 17 19 1 #Up
23 19 20 1
24 18 21 1 #Down
25 16 22 1 #Up
26 13 22 1 #Up
27 9 23 1
28 22 23 1
29 23 24 1 #Down
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