KEGG   REACTION: R07165
Entry
R07165                      Reaction                               
Name
L-aspartate:NADP+ oxidoreductase (deaminating)
Definition
L-Aspartate + H2O + NADP+ <=> Oxaloacetate + Ammonia + NADPH + H+
Equation
Comment
two-step reaction (see R07407+R13023)
Reaction class
RC00001  C00005_C00006
RC00006  C00036_C00049
RC02799  C00014_C00049
Enzyme
Other DBs
RHEA: 11787
LinkDB

KEGG   REACTION: R07407
Entry
R07407                      Reaction                               
Name
L-aspartate:NADP+ oxidoreductase (deaminating)
Definition
L-Aspartate + NADP+ <=> Iminoaspartate + NADPH + H+
Equation
Comment
the first step of two-step reaction (see R07165, R07407+R13023)
Reaction class
RC00001  C00005_C00006
RC02566  C00049_C05840
Enzyme
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00115  NAD biosynthesis, aspartate => quinolinate => NAD
Orthology
K06989  aspartate dehydrogenase [EC:1.4.1.21]
Reference
1  [PMID:12496312]
  Authors
Yang Z, Savchenko A, Yakunin A, Zhang R, Edwards A, Arrowsmith C, Tong L
  Title
Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643.
  Journal
J Biol Chem 278:8804-8 (2003)
DOI:10.1074/jbc.M211892200
Other DBs
RHEA: 42447
LinkDB

KEGG   REACTION: R13023
Entry
R13023                      Reaction                               
Definition
Iminoaspartate + H2O <=> Oxaloacetate + Ammonia
Equation
Comment
spontaneous
the second step of two-step reaction (see R07164, R07410+R13023 / R07165, R07407+R13023)
Reaction class
RC03275  C00036_C05840
Enzyme
LinkDB

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