KEGG   REACTION: R07603
Entry
R07603                      Reaction                               

Definition
(S)-3-Methyl-2-oxopentanoic acid + Thiamin diphosphate <=> 2-Methyl-1-hydroxybutyl-ThPP + CO2
Equation
Comment
Oxo-acid dehydrogenase complexes (see R04225), subsequently R07604
Reaction class
RC00027  C00068_C15978
RC02949  C00671_C15978
Enzyme
Pathway
rn00280  Valine, leucine and isoleucine degradation
Orthology
K00166  2-oxoisovalerate dehydrogenase E1 component alpha subunit [EC:1.2.4.4]
K00167  2-oxoisovalerate dehydrogenase E1 component beta subunit [EC:1.2.4.4]
K11381  2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]
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KEGG   REACTION: R07604
Entry
R07604                      Reaction                               

Definition
2-Methyl-1-hydroxybutyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine + Thiamin diphosphate
Equation
Comment
Oxo-acid dehydrogenase complexes (see R04225), following after R07603
Reaction class
RC00027  C00068_C15978
RC00627  C15972_C15979
RC02953  C15978_C15979
Enzyme
Pathway
rn00280  Valine, leucine and isoleucine degradation
Orthology
K00166  2-oxoisovalerate dehydrogenase E1 component alpha subunit [EC:1.2.4.4]
K00167  2-oxoisovalerate dehydrogenase E1 component beta subunit [EC:1.2.4.4]
K11381  2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]
LinkDB

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