KEGG   REACTION: R07644
Entry
R07644                      Reaction                               
Name
2,3-dihydroxybenzoate:L-serine ligase
Definition
6 ATP + 3 2,3-Dihydroxybenzoate + 3 L-Serine <=> Enterochelin + 6 AMP + 6 Diphosphate
Equation
6 C00002 + 3 C00196 + 3 C00065 <=> C05821 + 6 C00020 + 6 C00013
Comment
multi-step reaction
Reaction class
RC00162  C00196_C05821
RC03046  C00065_C05821
Enzyme
6.3.2.14
Pathway
rn01053  Biosynthesis of siderophore group nonribosomal peptides
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.14
     R07644  6 ATP + 3 2,3-Dihydroxybenzoate + 3 L-Serine <=> Enterochelin + 6 AMP + 6 Diphosphate
Orthology
K01252  bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14]
K02362  enterobactin synthetase component D / holo-[acyl-carrier protein] synthase [EC:6.3.2.14 2.7.8.7]
K02363  2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71]
K02364  L-serine---[L-seryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.72]
Other DBs
RHEA: 30574
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