KEGG   REACTION: R08225
Entry
R08225                      Reaction                               
Definition
Tegafur + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 5-FU + Succinic aldehyde + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C12673 + C03024 + C00007 <=> C07649 + C16835 + C03161 + C00001
Comment
CYP2A6
multi-step reaction
intermediate (5'-hydroxytegafur)
Reaction class
RC00063  C07649_C12673
RC02297  C12673_C16835
Enzyme
1.14.14.-
Pathway
rn00983  Drug metabolism - other enzymes
Orthology
K17683  cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-]
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