REACTION: R08237
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Entry
R08237 Reaction
Name
6-thioinosine 5'-monophosphate:diphosphate phospho-D-ribosyltransferase
Definition
6-Mercaptopurine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Thioinosine-5'-monophosphate + Diphosphate
Equation
C02380
+
C00119
<=>
C04646
+
C00013
Reaction class
RC00122
C02380_C04646
Enzyme
2.4.2.8
Pathway
rn00983
Drug metabolism - other enzymes
Brite
Enzymatic reactions [BR:
br08201
]
2. Transferase reactions
2.4 Glycosyltransferases
2.4.2 Pentosyltransferases
2.4.2.8
R08237 6-Mercaptopurine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Thioinosine-5'-monophosphate + Diphosphate
BRITE hierarchy
Orthology
K00760
hypoxanthine phosphoribosyltransferase [EC:
2.4.2.8
]
LinkDB
All DBs
RCLASS: RC00122
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Entry
RC00122 RClass
Definition
N4y-N5x:C1y-*:C8x+C8y-C8x+C8y
Reactant pair
C00371_C16443
C00385_C00655
C00385_C01762
C02380_C04646
C02860_C04422
C15586_C15587
C15587_C20463
C16352_C16353
C16614_C16615
Related class
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Reaction
R02142
R02143
R02297
R02341
R04071
R07918
R08075
R08237
R08238
R08368
R10244
Enzyme
2.4.1.118
2.4.1.-
2.4.2.1
2.4.2.8
2.4.2.22
3.2.2.1
3.2.2.25
Pathway
rn00230
Purine metabolism
rn00232
Caffeine metabolism
rn00908
Zeatin biosynthesis
rn00983
Drug metabolism - other enzymes
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
rn01232
Nucleotide metabolism
Orthology
K00760
hypoxanthine phosphoribosyltransferase [EC:
2.4.2.8
]
K00769
xanthine phosphoribosyltransferase [EC:
2.4.2.22
]
K01239
purine nucleosidase [EC:
3.2.2.1
]
K03783
purine-nucleoside phosphorylase [EC:
2.4.2.1
]
K03784
purine-nucleoside phosphorylase [EC:
2.4.2.1
]
K03816
xanthine phosphoribosyltransferase [EC:
2.4.2.22
]
K09913
purine/pyrimidine-nucleoside phosphorylase [EC:
2.4.2.1
2.4.2.2
]
K13493
cytokinin-N-glucosyltransferase [EC:2.4.1.-]
K15780
bifunctional protein TilS/HprT [EC:
6.3.4.19
2.4.2.8
]
K19836
hypoxanthine phosphoribosyltransferase [EC:
2.4.2.8
]
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integrated database retrieval system
