| Entry |
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| Definition |
4-Hydroxy-3-polyprenylbenzoate + Oxygen <=> 3,4-Dihydroxy-5-polyprenylbenzoate + H2O
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| Equation |
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| Comment |
general reaction (see R06865, n=5-9)
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| Reaction class |
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| Enzyme |
1.14.13.-
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| Pathway |
| rn00130 | Ubiquinone and other terpenoid-quinone biosynthesis |
| rn01110 | Biosynthesis of secondary metabolites |
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| Module |
| M00128 | Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinol |
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| Orthology |
| K06126 | ubiquinone biosynthesis monooxygenase Coq6 [EC:1.14.13.-] |
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| Reference |
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| Authors |
Ozeir M, Muhlenhoff U, Webert H, Lill R, Fontecave M, Pierrel F. |
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| Title |
Coenzyme Q biosynthesis: Coq6 is required for the C5-hydroxylation reaction and substrate analogs rescue Coq6 deficiency. |
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| Journal |
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| Reference |
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| Authors |
Ismail A, Leroux V, Smadja M, Gonzalez L, Lombard M, Pierrel F, Mellot-Draznieks C, Fontecave M. |
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| Title |
Coenzyme Q Biosynthesis: Evidence for a Substrate Access Channel in the FAD-Dependent Monooxygenase Coq6. |
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| Journal |
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| LinkDB |
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