KEGG   REACTION: R09575
Entry
R09575                      Reaction                               
Name
germacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating)
Definition
Germacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Costunolide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Equation
C19678 + C03024 + C00007 <=> C09382 + C03161 + 2 C00001
Comment
two-step reaction (see R12131+R12132)
Reaction class
RC02572  C09382_C19678
Enzyme
1.14.14.150
Pathway
rn00909  Sesquiterpenoid and triterpenoid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K20561  costunolide synthase [EC:1.14.14.150]
Other DBs
RHEA: 28233
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