KEGG   REACTION: R09579
Entry
R09579                      Reaction                               
Name
L-phenylalanine,NADPH:oxygen oxidoreductase (N-hydroxylating)
Definition
L-Phenylalanine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N-Hydroxy-L-phenylalanine + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C00079 + C00007 + C03024 <=> C19712 + C03161 + C00001
Comment
the first step of three-step reaction (see R09578, R09579+R09580+R09581)
Reaction class
RC00001  C00005_C00006
RC00365  C00079_C19712
Enzyme
1.14.14.40
Pathway
rn00460  Cyanoamino acid metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.40
     R09579  L-Phenylalanine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N-Hydroxy-L-phenylalanine + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K12153  phenylalanine N-monooxygenase [EC:1.14.14.40]
Other DBs
RHEA: 24995
LinkDB

KEGG   REACTION: R09580
Entry
R09580                      Reaction                               
Name
N-hydroxy-L-phenylalanine,NADPH:oxygen oxidoreductase (N-hydroxylating)
Definition
N-Hydroxy-L-phenylalanine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N,N-Dihydroxy-L-phenylalanine + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C19712 + C00007 + C03024 <=> C19715 + C03161 + C00001
Comment
the second step of three-step reaction (see R09578, R09579+R09580+R09581)
Reaction class
RC00001  C00005_C00006
RC01918  C19712_C19715
Enzyme
1.14.14.40
Pathway
rn00460  Cyanoamino acid metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.40
     R09580  N-Hydroxy-L-phenylalanine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N,N-Dihydroxy-L-phenylalanine + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K12153  phenylalanine N-monooxygenase [EC:1.14.14.40]
Other DBs
RHEA: 24999
LinkDB

KEGG   REACTION: R09581
Entry
R09581                      Reaction                               
Definition
N,N-Dihydroxy-L-phenylalanine <=> (E)-Phenylacetaldoxime + CO2 + H2O
Equation
C19715 <=> C19714 + C00011 + C00001
Comment
the last step of three-step reaction (see R09578, R09579+R09580+R09581)
Reaction class
RC01936  C19714_C19715
Enzyme
1.14.14.40
Pathway
rn00460  Cyanoamino acid metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.40
     R09581  N,N-Dihydroxy-L-phenylalanine <=> (E)-Phenylacetaldoxime + CO2 + H2O
Orthology
K12153  phenylalanine N-monooxygenase [EC:1.14.14.40]
Other DBs
RHEA: 25003
LinkDB

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