REACTION: R10170
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Entry
R10170 Reaction
Name
(2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)
Definition
(2R,3S)-3-Isopropylmalate <=> alpha-Isopropylmalate
Equation
C04411
<=>
C02504
Reaction class
RC03072
C02504_C04411
Enzyme
4.2.1.33
Pathway
rn01210
2-Oxocarboxylic acid metabolism
rn01230
Biosynthesis of amino acids
Brite
Enzymatic reactions [BR:
br08201
]
4. Lyase reactions
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33
R10170 (2R,3S)-3-Isopropylmalate <=> alpha-Isopropylmalate
BRITE hierarchy
Orthology
K01702
3-isopropylmalate dehydratase [EC:
4.2.1.33
]
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
K01704
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:
4.2.1.33
4.2.1.35
]
K21359
3-isopropylmalate/methylthioalkylmalate dehydratase small subunit [EC:
4.2.1.33
4.2.1.170
]
Other DBs
RHEA:
32290
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All DBs
RCLASS: RC03072
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Entry
RC03072 RClass
Definition
C1b-C1c:*-O1a:C1d+C6a-C1c+C6a
C1d-C1c:O1a-*:C1b+C1c+C6a-C1c+C1c+C6a
O1a-O1a:C1d+*-*+C1c:*-*
Reactant pair
C02504_C04411
Related class
DB search
Reaction
R10170
Enzyme
4.2.1.33
Pathway
rn01210
2-Oxocarboxylic acid metabolism
rn01230
Biosynthesis of amino acids
RModule
RM001
2-Oxocarboxylic acid chain extension by tricarboxylic acid pathway
Orthology
K01702
3-isopropylmalate dehydratase [EC:
4.2.1.33
]
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
K01704
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:
4.2.1.33
4.2.1.35
]
K21359
3-isopropylmalate/methylthioalkylmalate dehydratase small subunit [EC:
4.2.1.33
4.2.1.170
]
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