KEGG   REACTION: R10391
Entry
R10391                      Reaction                               
Name
(R)-(homo)2-citrate hydro-lyase [(-)-threo-iso(homo)2-citrate forming]
Definition
(R)-(Homo)2-citrate <=> (-)-threo-Iso(homo)2-citrate
Equation
C16583 <=> C16597
Comment
two-step reaction (see R10392+R10393)
Reaction class
RC00497  C16583_C16597
Enzyme
4.2.1.114
Pathway
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
rn01240  Biosynthesis of cofactors
Module
M00608  2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.114
     R10391  (R)-(Homo)2-citrate <=> (-)-threo-Iso(homo)2-citrate
Orthology
K16792  methanogen homoaconitase large subunit [EC:4.2.1.114]
K16793  methanogen homoaconitase small subunit [EC:4.2.1.114]
Reference
1  [PMID:10940051]
  Authors
Howell DM, Graupner M, Xu H, White RH
  Title
Identification of enzymes homologous to isocitrate dehydrogenase that are involved in coenzyme B and leucine biosynthesis in methanoarchaea.
  Journal
J Bacteriol 182:5013-6 (2000)
DOI:10.1128/JB.182.17.5013-5016.2000
LinkDB

DBGET integrated database retrieval system