KEGG   REACTION: R11383
Entry
R11383                      Reaction                               
Name
aurachin C:NADPH:oxygen oxidoreductase (4-hydroxy-2-methyl-3-oxo-4-farnesyl-3,4-dihydroquinoline-1-oxide-forming)
Definition
Aurachin C + NADPH + H+ + Oxygen <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADP+ + H2O
Equation
C21330 + C00005 + C00080 + C00007 <=> C21141 + C00006 + C00001
Comment
two-step reaction (see R11385+R11386)
Reaction class
RC03422  C21141_C21330
Enzyme
1.14.13.222
Pathway
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00848  Aurachin biosynthesis, anthranilate => aurachin A
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.222
     R11383  Aurachin C + NADPH + H+ + Oxygen <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADP+ + H2O
Orthology
K21272  aurachin C monooxygenase/isomerase [EC:1.14.13.222]
Other DBs
RHEA: 49007
LinkDB

KEGG   REACTION: R11385
Entry
R11385                      Reaction                               
Name
aurachin C:NADPH:oxygen oxidoreductase (aurachin-C-epoxide-forming)
Definition
Aurachin C + NADPH + H+ + Oxygen <=> Aurachin C epoxide + NADP+ + H2O
Equation
C21330 + C00005 + C00080 + C00007 <=> C21331 + C00006 + C00001
Comment
the first step of two-step reaction (see R11383, R11385+R11386)
Reaction class
RC03423  C21330_C21331
Enzyme
1.14.13.222
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.222
     R11385  Aurachin C + NADPH + H+ + Oxygen <=> Aurachin C epoxide + NADP+ + H2O
Other DBs
RHEA: 49011
LinkDB

KEGG   REACTION: R11386
Entry
R11386                      Reaction                               
Name
aurachin-C-epoxide mutase
Definition
Aurachin C epoxide <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide
Equation
C21331 <=> C21141
Comment
the second step of two-step reaction (see R11382, R11384+R11386)
the second step of two-step reaction (see R11383, R11385+R11386)
Reaction class
RC03424  C21141_C21331
Enzyme
1.14.13.222
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.222
     R11386  Aurachin C epoxide <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide
LinkDB

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