KEGG   REACTION: R11449
Entry
R11449                      Reaction                               
Name
tetracycline,NADPH:oxygen oxidoreductase (11a-hydroxylating)
Definition
Tetracycline + NADPH + H+ + Oxygen <=> 11a-Hydroxytetracycline + NADP+ + H2O
Equation
C06570 + C00005 + C00080 + C00007 <=> C21391 + C00006 + C00001
Reaction class
RC03438  C06570_C21391
Enzyme
1.14.13.231
Pathway
rn00253  Tetracycline biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.231
     R11449  Tetracycline + NADPH + H+ + Oxygen <=> 11a-Hydroxytetracycline + NADP+ + H2O
Orthology
K18221  tetracycline 11a-monooxygenase, tetracycline resistance protein [EC:1.14.13.231]
Other DBs
RHEA: 50007
LinkDB

KEGG   RCLASS: RC03438
Entry
RC03438                     RClass                                 
Definition
C1z-C2y:O1a-*:C1y+C5x+C5x-C1y+C2y+C5x
C5x-C2y:*-*:C1z+C1z+O5x-C1z+C2y+O1a
Reactant pair
C06570_C21391    C06571_C21439    C06624_C21438
Related class
Reaction
R11449 R11525 R11526
Enzyme
1.14.13.231
Pathway
rn00253  Tetracycline biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K18221  tetracycline 11a-monooxygenase, tetracycline resistance protein [EC:1.14.13.231]

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