REACTION: R11478
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Entry
R11478 Reaction
Name
tetracycline:FADH2 oxidoreductase (7-halogenating)
Definition
Tetracycline + FADH2 + Cl- + Oxygen + H+ <=> Chlortetracycline + FAD + 2 H2O
Equation
C06570
+
C01352
+
C00698
+
C00007
+
C00080
<=>
C06571
+
C00016
+ 2
C00001
Reaction class
RC00949
C06570_C06571
Enzyme
1.14.19.49
Pathway
rn00253
Tetracycline biosynthesis
rn01057
Biosynthesis of type II polyketide products
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
Module
M00823
Chlortetracycline biosynthesis, pretetramide => chlortetracycline
Orthology
K14257
tetracycline 7-halogenase / FADH2 O2-dependent halogenase [EC:
1.14.19.49
1.14.19.-]
Other DBs
RHEA:
50715
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