KEGG   REACTION: R11711
Entry
R11711                      Reaction                               
Name
L-arginine,reduced-flavodoxin:oxygen oxidoreductase (nitric-oxide-forming)
Definition
2 L-Arginine + 3 Reduced flavodoxin + 4 Oxygen <=> 2 L-Citrulline + 2 Nitric oxide + 3 Oxidized flavodoxin + 4 H2O
Equation
2 C00062 + 3 C02745 + 4 C00007 <=> 2 C00327 + 2 C00533 + 3 C02869 + 4 C00001
Comment
two-step reaction (see R11712+R11713)
Reaction class
RC00177  C00062_C00327
Enzyme
1.14.14.47
Pathway
rn00220  Arginine biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.47
     R11711  2 L-Arginine + 3 Reduced flavodoxin + 4 Oxygen <=> 2 L-Citrulline + 2 Nitric oxide + 3 Oxidized flavodoxin + 4 H2O
Orthology
K00491  nitric-oxide synthase, bacterial [EC:1.14.14.47]
Other DBs
RHEA: 52327
LinkDB

KEGG   REACTION: R11712
Entry
R11712                      Reaction                               
Definition
2 L-Arginine + 2 Reduced flavodoxin + 2 Oxygen <=> 2 N(omega)-Hydroxyarginine + 2 Oxidized flavodoxin + 2 H2O
Equation
2 C00062 + 2 C02745 + 2 C00007 <=> 2 C05933 + 2 C02869 + 2 C00001
Comment
the first step of two-step reaction (see R11711, R11712+R11713)
Reaction class
RC00330  C00062_C05933
Enzyme
1.14.14.47
Pathway
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.47
     R11712  2 L-Arginine + 2 Reduced flavodoxin + 2 Oxygen <=> 2 N(omega)-Hydroxyarginine + 2 Oxidized flavodoxin + 2 H2O
Orthology
K00491  nitric-oxide synthase, bacterial [EC:1.14.14.47]
Other DBs
RHEA: 52331
LinkDB

KEGG   REACTION: R11713
Entry
R11713                      Reaction                               
Definition
2 N(omega)-Hydroxyarginine + Reduced flavodoxin + 2 Oxygen <=> 2 L-Citrulline + 2 Nitric oxide + Oxidized flavodoxin + 2 H2O
Equation
2 C05933 + C02745 + 2 C00007 <=> 2 C00327 + 2 C00533 + C02869 + 2 C00001
Comment
the second step of two-step reaction (see R11711, R11712+R11713)
Reaction class
RC01044  C00327_C05933
Enzyme
1.14.14.47
Pathway
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.47
     R11713  2 N(omega)-Hydroxyarginine + Reduced flavodoxin + 2 Oxygen <=> 2 L-Citrulline + 2 Nitric oxide + Oxidized flavodoxin + 2 H2O
Orthology
K00491  nitric-oxide synthase, bacterial [EC:1.14.14.47]
Other DBs
RHEA: 52335
LinkDB

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