KEGG   REACTION: R11978
Entry
R11978                      Reaction                               
Name
ent-isokaurene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
Definition
ent-2alpha-Hydroxyisokaurene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> ent-2alpha,3alpha-Dihydroxyisokaurene + H2O + [Oxidized NADPH---hemoprotein reductase]
Equation
C20146 + C00007 + C03024 <=> C21831 + C00001 + C03161
Comment
the second step of two-step reaction (see R12058, R09861+R11978)
Reaction class
RC01993  C20146_C21831
Enzyme
1.14.14.76
Pathway
rn00904  Diterpenoid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.76
     R11978  ent-2alpha-Hydroxyisokaurene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> ent-2alpha,3alpha-Dihydroxyisokaurene + H2O + [Oxidized NADPH---hemoprotein reductase]
Orthology
K16083  ent-isokaurene hydroxylase [EC:1.14.14.76]
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