KEGG   REACTION: R12300
Entry
R12300                      Reaction                               
Name
malonate:CoA ligase (AMP-forming)
Definition
ATP + Malonate + CoA <=> AMP + Diphosphate + Malonyl-CoA
Equation
Enzyme
Pathway
rn00061  Fatty acid biosynthesis
rn01100  Metabolic pathways
rn01212  Fatty acid metabolism
Orthology
K18660  malonyl-CoA/methylmalonyl-CoA synthetase [EC:6.2.1.76 6.2.1.-]
Reference
1  [PMID:30201289]
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Reference
2  [PMID:21846720]
  Authors
Witkowski A, Thweatt J, Smith S
  Title
Mammalian ACSF3 protein is a malonyl-CoA synthetase that supplies the chain extender units for mitochondrial fatty acid synthesis.
  Journal
J Biol Chem 286:33729-36 (2011)
DOI:10.1074/jbc.M111.291591
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