KEGG   REACTION: R12848
Entry
R12848                      Reaction                               
Definition
22,26-Dihydroxycholesterol + 2-Oxoglutarate + Oxygen <=> 16alpha,22,26-Trihydroxycholesterol + Succinate + CO2
Equation
C22447 + C00026 + C00007 <=> C22448 + C00042 + C00011
Comment
16alpha-hydroxylase
Reaction class
RC00661  C22447_C22448
Enzyme
1.14.11.-
Pathway
rn00996  Biosynthesis of various alkaloids
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.-
     R12848  22,26-Dihydroxycholesterol + 2-Oxoglutarate + Oxygen <=> 16alpha,22,26-Trihydroxycholesterol + Succinate + CO2
Orthology
K25492  22,26-dihydroxycholesterol 16alpha-hydroxylase [EC:1.14.11.-]
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