REACTION: R13106
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Entry
R13106 Reaction
Name
fumagillol:NADP+ 5-oxidoreductase
Definition
Fumagillol + NADP+ <=> 5-Dehydrofumagillol + NADPH + H+
Equation
C22618
+
C00006
<=>
C22619
+
C00005
+
C00080
Enzyme
1.1.1.437
Pathway
rn00998
Biosynthesis of various antibiotics
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
Module
M00969
Fumagillin biosynthesis, farnesyl-PP => fumagillin
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.437
R13106 Fumagillol + NADP+ <=> 5-Dehydrofumagillol + NADPH + H+
BRITE hierarchy
Orthology
K22572
5-dehydrofumagillol 5-reductase [EC:
1.1.1.437
]
Other DBs
RHEA:
74710
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