KEGG   REACTION: R13420
Entry
R13420                      Reaction                               
Name
urea amidohydrolase
Definition
Urea + 2 H2O <=> HCO3- + 2 Ammonia
Equation
C00086 + 2 C00001 <=> C00288 + 2 C00014
Comment
two-step reaction (see R13421+R12185)
Reaction class
RC02798  C00014_C00086
Enzyme
3.5.1.5
Pathway
rn00220  Arginine biosynthesis
rn00230  Purine metabolism
rn00791  Atrazine degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.5
     R13420  Urea + 2 H2O <=> HCO3- + 2 Ammonia
Orthology
K01427  urease [EC:3.5.1.5]
K01428  urease subunit alpha [EC:3.5.1.5]
K01429  urease subunit beta [EC:3.5.1.5]
K01430  urease subunit gamma [EC:3.5.1.5]
K14048  urease subunit gamma/beta [EC:3.5.1.5]
LinkDB

KEGG   REACTION: R13421
Entry
R13421                      Reaction                               
Definition
Urea + H2O <=> Carbamate + Ammonia
Equation
C00086 + C00001 <=> C01563 + C00014
Comment
the first step of the two-step reaction (see R13420, R13421+R12185)
Enzyme
3.5.1.5
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.5
     R13421  Urea + H2O <=> Carbamate + Ammonia
LinkDB

KEGG   REACTION: R12185
Entry
R12185                      Reaction                               
Definition
Ammonia + HCO3- <=> Carbamate + H2O
Equation
C00014 + C00288 <=> C01563 + C00001
Comment
spontaneous
the second step of the two-step reaction (see R00150, R01395+R12185, ec 2.7.2.2)
the second step of the two-step reaction (see R13420, R13421+R12185, ec 3.5.1.5)
Enzyme
2.7.2.2         3.5.1.5
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.2
     R12185  Ammonia + HCO3- <=> Carbamate + H2O
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.5
     R12185  Ammonia + HCO3- <=> Carbamate + H2O
LinkDB

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