KEGG   Amycolatopsis acidiphila: LWP59_07265
Entry
LWP59_07265       CDS       T07896                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
aacd  Amycolatopsis acidiphila
Pathway
aacd03030  DNA replication
aacd03410  Base excision repair
aacd03420  Nucleotide excision repair
aacd03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:aacd00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    LWP59_07265 (ligA)
   03410 Base excision repair
    LWP59_07265 (ligA)
   03420 Nucleotide excision repair
    LWP59_07265 (ligA)
   03430 Mismatch repair
    LWP59_07265 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:aacd03032]
    LWP59_07265 (ligA)
   03400 DNA repair and recombination proteins [BR:aacd03400]
    LWP59_07265 (ligA)
Enzymes [BR:aacd01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     LWP59_07265 (ligA)
DNA replication proteins [BR:aacd03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     LWP59_07265 (ligA)
DNA repair and recombination proteins [BR:aacd03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     LWP59_07265 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     LWP59_07265 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     LWP59_07265 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      LWP59_07265 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD HHH_5 PTCB-BRCT Nlig-Ia HHH HHH_8 BRCT_2
Other DBs
NCBI-ProteinID: UIJ61419
LinkDB
Position
1482996..1485113
AA seq 705 aa
MSEAQDVTDVPAEVRERYGALADEVRGHQFRYYVLDSPTISDGQFDELLHRLEAMEAEYP
SLVTPESPTQNVGGTFSTEFAAYDHLERMLSLDNVFDTEEMLAWIERVEREVGGSTQYLA
ELKIDGLAINLLYEQGKLTRALTRGDGRTGEDVTLNVRTLDQVPDRLTGTDEFPVPALVE
VRGEVFFRVEDFLELNAKLVEAGKPPFANPRNTAAGSLRQKDPRVTRSRRLRLICHGLGR
REGFEPGRQSEAYDALRAWGLPVSTHTKVFTTAEEVLDHIRYWGEHRHDAEHEIDGIVIK
VDQVSLQRRLGTTSRAPRWAIAYKYAPEEAITKLLDIQVNVGRTGRVTPFAVMEPVKVAG
STVAMATLHNAEEVKRKGVLIGDRVVIRKAGDVIPEVLGPVADARTGDEREFVMPTRCPE
CFTPLAHQKEGDVDIRCPNARSCPAQLRERLFHLAGRGAFDIEVLGYEAATALLESGVVV
DEGDIFDLDTEKLERVELFRTKAGDLSANARKLLANLDTAKDRPLWKVLVGLSIRHVGPT
AAQALAREFGSLEAIEAASEEELADVDGVGPTIAAAVEEWFGVDWHREVVDKWRRAGVRM
AEERDESIPRNLEGLSIVVTGSLSTYSRDEAKEAIMSRGGKAAGSVSKKTAFVVVGDAPG
SKYDKAVQLKVPVLDEGGFQVLLDRGPDAAAEVALPAGEEEPADE
NT seq 2118 nt   +upstreamnt  +downstreamnt
gtgagtgaagctcaggacgtgacggacgtgcccgccgaggtacgggagcggtacggcgcg
ctggcggacgaggtccgcggccaccagttccgctactacgtgctggactcgccgacgatc
tccgacggtcagttcgacgagctgctgcaccggctcgaggccatggaggcggagtacccg
tccctggtaacgccggagtcgccgacgcagaacgtgggcggcacgttctccaccgagttc
gccgcgtacgaccatctcgagcgcatgctcagcctggacaacgtcttcgacaccgaggag
atgctcgcctggatcgagcgcgtcgagcgcgaggtcggcgggtccacgcagtacctggcg
gagctgaagatcgacgggctggccatcaacctgctctacgaacagggcaagctcacacgc
gcgctcacccgcggcgacgggcgcacgggtgaggacgtcacgctgaacgtccgcaccctc
gaccaggtgccggacaggctcaccggcaccgacgagttcccggtgcccgcgctggtcgag
gtgcgcggcgaggtgttcttccgcgtcgaggacttcctggagctgaacgcgaagctcgtc
gaggcgggcaagccgccgttcgcgaacccgcgcaacacggcggcgggatcgttgcggcag
aaggatccccgtgtcacccgcagccgtcgcctgcggctgatctgccacggcctcggcaga
cgcgagggcttcgagcccgggcgccagtcggaggcgtacgacgcgctgcgggcgtggggc
ctgccggtgtccacgcacaccaaggtcttcaccaccgcggaggaggtgctcgaccacatc
cggtactggggcgagcaccggcacgacgccgagcacgagatcgacggcatcgtgatcaag
gtcgaccaggtgtcgctgcagcgcaggctcggcaccacgtcgcgggcgccgcgctgggcg
atcgcgtacaagtacgcgccggaggaggcgatcacgaagctgctcgacatccaggtgaac
gtcgggcgcaccggccgggtcacgccgttcgcggtgatggagccggtgaaagtggccggg
tcgacggtcgccatggccaccctgcacaacgccgaggaggtcaagcgcaagggcgtgctg
atcggcgacagggtggtcatccgcaaggccggtgacgtgatccccgaggtgctcggcccg
gtcgccgacgcccgcacgggtgacgagcgcgagttcgtgatgcccacccggtgcccggag
tgcttcacgccgctggcgcaccagaaggagggcgacgtcgacatccgctgcccgaacgcg
cgctcgtgtcccgcgcagctgcgggagcggctgttccacctggccgggcgcggcgcgttc
gacatcgaggtgctgggctacgaggcggccaccgcgctgctggagtccggggtggtggtc
gacgagggcgacatcttcgacctggacaccgagaagctcgagcgggtggagctgttccgc
accaaggccggtgacctgtcggccaacgcgcgcaagctgctggcgaacctggacacggcg
aaggaccgtccgctctggaaggtgctggtgggcctgtccatcaggcatgtcggcccgacg
gcggcgcaggcgctcgcgcgcgagttcggctcgctggaggcgatcgaggccgcgagcgag
gaggaactggccgatgtggacggtgtcggcccgaccatcgcggcggcggtggaggagtgg
ttcggcgtcgactggcaccgcgaggtcgtggacaagtggcgccgtgcgggggtccggatg
gcggaggagcgggacgagtcgatcccgcgcaacctcgagggcctctcgatcgtcgtgacg
ggctcgctgtcgacgtactcgcgggacgaggccaaggaagccatcatgtcgcgcggtggc
aaggcggcgggttcggtgtcgaagaagacggcgttcgtcgtggtgggggacgcaccgggc
tcgaagtacgacaaggcggtgcagctgaaggtcccggtgctcgacgagggcggcttccag
gtgctgctggaccggggccccgacgccgcggcggaggtggccctgcccgccggcgaggag
gagcccgccgatgagtga

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