Amycolatopsis acidiphila: LWP59_33085
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Entry
LWP59_33085 CDS
T07896
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
aacd
Amycolatopsis acidiphila
Pathway
aacd00020
Citrate cycle (TCA cycle)
aacd00630
Glyoxylate and dicarboxylate metabolism
aacd00785
Lipoic acid metabolism
aacd01100
Metabolic pathways
aacd01110
Biosynthesis of secondary metabolites
aacd01120
Microbial metabolism in diverse environments
aacd01200
Carbon metabolism
aacd01210
2-Oxocarboxylic acid metabolism
Module
aacd_M00009
Citrate cycle (TCA cycle, Krebs cycle)
aacd_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
aacd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
LWP59_33085
00630 Glyoxylate and dicarboxylate metabolism
LWP59_33085
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LWP59_33085
Enzymes [BR:
aacd01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
LWP59_33085
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
LWP59_33085
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
LWP59_33085
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
LWP59_33085
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
UIJ58870
LinkDB
All DBs
Position
6769716..6773384
Genome browser
AA seq
1222 aa
AA seq
DB search
MSSSSPASQFGPNEWLVEEMYDQFLADPSSVDAAWHDFFSDFKPTQTPETKPDTAGSSAP
AAQTPPPKPSTNGKATTAKTAAQSAPAAKPQPATAKPQAAAAKPATDEETKQLRGAAAAI
AKNMDASLSVPTATSVRAVPAKLMADNRIVINNHLKRTRGGKISFTHLIGYAMVRALHDY
PNMNRHYQLADGKPFAVTPEHVNLGLAIDMKGKDGSRTLVVASIKNTENMSFLQFWQAYE
DIVKKARNNKLTADDFAGTTISLTNPGGIGTNHSVPRLQAGQGAIIGVGAMQYPAHFEGT
SEKTLIDLGISKIMTLTSTYDHRIIQGAESGEFLKRIHELLLGEDGFYDDIFTSLRLPYE
PIRWVADIPAGAVDKTARVLELIDAYRMRGHLMADTDPLNYRQRRHEDLDVLSHGLTLWD
LDREFAVGGFAGQERMKLRDILGVLRDSYCRTVGIEYTHILDPEERRWIQERVEVPHAKP
DPAVQKYVLSKLNAAEAFETFLQTKYVGQKRFSLEGGETVIPLLDTVLDKAAEHELDEVV
IGMPHRGRLNVLANIVGKPISQIFREFEGNLDPGQAHGSGDVKYHLGAEGKYFRMFGDGE
TKVSLASNPSHLETVDPVLEGIVRAKQDILDKGDQDGQGFTVLPVLMHGDAAFAGQGVVA
ETLNLALLRGYRTGGSVHLIINNQVGFTTAPEHARSSQYATDVAKMIGAPIFHVNGDDPE
AAHWVAKLAVDYRQAFNKDVVIDMICYRRRGHNEGDDPSMTQPAMYDIIDTKRSVRKTYT
EALIGRGDISVDEAEAALRDFSSQLEHVFNEVRELEKHPAKASPSVEEEQQVPAKVPTAV
AREVIERIGDAFLNVPEGFSPHPRVKPVLERRAKMSREGGIDWAFGELLAFGSLAMEGRL
VRLSGQDSRRGTFTQRHSVLIDRKSGQEYAPLQSLTDDQARVMIYDSALSEYAAVGFEYG
YSVANSEALVLWEAQFGDFVNGAQTVIDEYISSGEAKWGQLSDVVLLLPHGHEGQGPDHT
SGRIERFLQLCAEGSMTVAVPSTPANYFHLLRRHALDGIRRPMIVFTPKSMLRNKAATSA
VEDFVGQSKFMSVIDDKEVDPAKVRKVLLTSGKLYWELVAERTKREANDVAIVRIEQYYP
LPTKKLRAALERYTAASKVSWVQEEPENQGGWPFFGLHLPRKLPELLSGLDVVSRRPMAA
PSAGSSKVHEVEQKALIAKAFE
NT seq
3669 nt
NT seq
+upstream
nt +downstream
nt
gtgtccagcagcagccctgcgtcacagttcggccccaacgaatggctcgtcgaggagatg
tacgaccagttcctcgccgacccttcctcagtagatgccgcctggcatgacttcttctcc
gacttcaagccgacgcagacgccggagaccaagccggacaccgcgggcagcagcgccccc
gccgcgcagaccccgccgccgaagccgtcgacgaacggcaaggccaccacggcgaagacc
gccgcacagtccgctcccgccgccaagccgcagcccgccaccgcgaagccgcaggcggcc
gccgcgaagccggccacggacgaggagaccaagcagctgcgtggcgccgccgccgcgatc
gcgaagaacatggacgcctcgctgagcgtcccgaccgcgaccagcgtgcgtgccgtgccc
gccaagctgatggccgacaaccgcatcgtcatcaacaaccacctcaagcgcacccgcggc
gggaagatctccttcacccacctcatcgggtacgcgatggtccgcgcgctgcacgactac
ccgaacatgaaccggcactaccagctggcggacgggaagccgttcgcggtcacgccggag
cacgtcaacctcggcctcgccatcgacatgaagggcaaggacggcagccgcaccctcgtg
gtcgcctccatcaagaacacggagaacatgtcgttcctccagttctggcaggcctacgag
gacatcgtcaagaaggcgcgcaacaacaagctcaccgcggacgacttcgcgggcaccacc
atctcgctgaccaacccgggcggcatcggcacgaaccactcggtgccgcggctgcaggcg
ggtcagggcgcgatcatcggcgtcggtgccatgcagtacccggcgcacttcgagggcacc
agcgagaagacgctgatcgacctgggcatcagcaagatcatgacgctgacctcgacctac
gaccaccgcatcatccagggcgcggagtccggcgagttcctcaagcgcatccatgagctg
ctgctcggcgaggacggcttctacgacgacatcttcacgtcgctgcggctgccctacgag
ccgatccgctgggtcgcggacatcccggcaggggcggtggacaagaccgcccgggtgctc
gagctgatcgacgcctaccggatgcgcggccacctgatggccgacaccgacccgctgaac
taccgccagcgccgccacgaggacctcgacgtcctctcgcacggcctgacgctgtgggac
ctcgaccgcgagttcgccgtcggcgggttcgccggccaggagcggatgaagctgcgcgac
atcctcggcgtcctgcgcgactcctactgccgcacggtcggcatcgagtacacccacatc
ctggacccggaggagcgccgctggatccaggagcgggtcgaggtgccgcacgcgaagccg
gaccccgccgtgcagaagtacgtgctgtccaagctgaacgcggcggaggccttcgagacc
ttcctgcagaccaagtacgtcggccagaagcggttctcgctcgaaggcggcgagacggtg
atcccgctgctggacaccgtgctggacaaggccgccgagcacgagctcgacgaggtcgtc
atcggcatgccgcaccgcggcaggctcaacgtgctggccaacatcgtcggcaagccgatc
tcgcagatcttccgcgagttcgagggcaacctcgacccgggccaggcgcacggctccggc
gacgtgaagtaccacctgggcgcggagggcaagtacttccgcatgttcggcgacggcgag
accaaggtctcgctggcgtccaacccgtcgcacctggagaccgtcgacccggtgctcgaa
ggcatcgtccgcgccaagcaggacatcctcgacaagggcgaccaggacggccagggcttc
accgtgctgccggtgctgatgcacggcgacgcggcgttcgccggccagggtgtggtcgcc
gagacgctgaacctggcgctgctgcgcgggtaccgcaccggcggcagcgtgcacctcatc
atcaacaaccaggtcggcttcaccaccgcgccggagcacgcgcgctcctcgcagtacgcc
acggacgtcgcgaagatgatcggcgcgccgatcttccacgtgaacggtgacgacccggag
gccgcgcactgggtggccaagctggcggtggactaccggcaggcgttcaacaaggacgtc
gtgatcgacatgatctgctaccgccgccgcggccacaacgagggcgacgacccttcgatg
acccagccggcgatgtacgacatcatcgacacgaagcggtcggtccgcaagacctacacc
gaggccctgatcggccgcggcgacatctccgtggacgaggccgaggccgcgctgcgcgac
ttctccagccagctcgagcacgtgttcaacgaggtgcgcgagctggagaagcacccggcg
aaggccagcccctcggtggaggaggagcagcaggtgccggccaaggtgccgaccgcggtg
gcccgcgaggtcatcgaacgcatcggcgacgcgttcctgaacgtgccggaaggcttcagc
ccgcacccgcgcgtcaagccggtgctggagcgccgcgcgaagatgtcgcgcgagggcggg
atcgactgggcgttcggcgagctgctcgcgttcggttcgctggcgatggaaggccggctg
gtccggctgtcgggccaggactcgcggcgcggcaccttcacccagcggcactcggtgctg
atcgaccgcaagtccggtcaggagtacgcgccgctgcagagcctgaccgacgaccaggcc
cgcgtgatgatctacgactcggcgctgtccgagtacgcggccgtcggcttcgagtacggc
tactcggtggccaactccgaggcgctggtgctgtgggaagcgcagttcggtgacttcgtc
aacggcgcgcagaccgtcatcgacgagtacatctcgtccggtgaagcgaagtggggccag
ctctcggacgtcgtgctgctgctgccgcacgggcacgagggtcagggcccggaccacacg
tcgggccgcatcgagcggttcctgcagctgtgcgccgagggctcgatgaccgtcgcggtg
ccctcgaccccggcgaactacttccacctgttgcgccggcacgccctcgacggcatccgg
cggccgatgatcgtcttcacgccgaagtcgatgctgcgcaacaaggcggcgacctccgcg
gtcgaggacttcgtgggccagtcgaagttcatgtcggtcatcgacgacaaggaagtggac
cccgccaaggtacggaaggtgctgctcacctcgggcaagctgtactgggagctggtcgcc
gagcgcaccaagcgcgaggcgaacgacgttgccatcgtccggatcgagcagtactacccg
ctgccgacgaagaagctgcgtgcggcgctggagcgctacacggctgcttcgaaggtcagc
tgggtccaggaggagccggagaaccagggcgggtggccgttcttcggcctgcacctgccg
cgcaagctgccggagctgctgtcgggcctggacgtcgtgtcccgccgcccgatggccgcc
ccctcggcgggctcgtcgaaggtgcacgaggtcgagcagaaggccctgatcgcgaaggcc
ttcgagtaa
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