Aggregatibacter actinomycetemcomitans 624: ACT75_07200
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Entry
ACT75_07200 CDS
T04753
Name
(GenBank) bifunctional glutamate--cysteine ligase/glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
aact
Aggregatibacter actinomycetemcomitans 624
Pathway
aact00270
Cysteine and methionine metabolism
aact00480
Glutathione metabolism
aact01100
Metabolic pathways
aact01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
aact00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
ACT75_07200
09106 Metabolism of other amino acids
00480 Glutathione metabolism
ACT75_07200
Enzymes [BR:
aact01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
ACT75_07200
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
ATP-grasp_3
RimK
Dala_Dala_lig_C
ATPgrasp_ST
GARS_A
KH_SLS1_2
GCS2
Motif
Other DBs
NCBI-ProteinID:
AMQ94328
UniProt:
A0A5D0EJC4
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Position
complement(1476286..1478559)
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AA seq
757 aa
AA seq
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MKIQQVIKENRLELLFQQGSFGIEKESQRVHADGSVVVSAHPKCFGSRSYHPYIQTDFAE
SQLELITPPNKKIEDTLRWLSAIHEVVLRTMPQDEYVFPLSMPAGLPPEDQIKVAQLENP
ADVAYREHLVQSYGKSKQMVSGVHYNFQLDPALIRQLFNGQNEYQSAVDFQNDLYLKVAR
NFLRYQWILVYLLAATPTVDANYFRGGTPLKPGQYVRSLRSSQYGYVNDPSVKISYDSLK
DYVNTLEHAVNSGQLIAEKEFYSNVRLRGAKHARELLQNGIQYLEFRLFDLNPFEPYGIA
LNDAKFVHYFILLMAWLDEESTESAVDLGKEKLAQVAWENPLSPTAFQSEGERVLQQLLA
MLTEIHAGAEIATIVKEKLAQFADPTLTLGARLVNAIEQHGGYQKLGAELAIRYKQQAFE
RFYALSAFDNMELSTQALMFDAIQKGLKIEILDERDQFLSLQFGDHLEYVKNGNMTSHDS
YISPLIMENKVVTKKVLAKAGFNVPQSVEFTGVEQAVANYALFAGRAVVIKPKSTNYGLG
ISIFQQGVHDREDFAKAIEIAFREDKEVIVEDYLTGTEYRFFVLGDETLAVLLRVPANVI
GDGVHTVAELVAQKNDHPLRGDGSRTPLKKIALGDIERLQLKEQGLTVDSVPAKDQLVQL
RANSNISTGGDSIDMTDQMHPSYKALAVGITKAMGAAVCGVDLIIPDLTKPAEPNLQSWG
VIEANFNPMMMMHIFPYAGQSRRVTQNVLKMLFPELK
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgaaaattcagcaggttataaaagagaatcgcttggaattgttgtttcagcagggttct
ttcggtattgaaaaagaaagccaacgcgtgcatgcggacggttccgttgtggtaagcgca
cacccgaaatgttttggcagccgttcttaccacccttatatccaaacggattttgccgag
agccagcttgaattaatcaccccgccgaataaaaaaattgaagataccctgcgttggtta
tccgctattcacgaagtggtgttacgcaccatgccgcaagatgaatatgtatttccgtta
agtatgccggcaggtttgccgccggaagatcaaatcaaagtagcgcaattggagaatccg
gcagatgtggcatatcgtgagcatttggtgcaatcctacggcaaaagcaaacaaatggtg
agcggtgttcactataatttccaactggatcccgctctaatccggcagctttttaacggg
caaaatgaataccaaagtgcggtggattttcagaacgatttatatttgaaagttgcccgc
aatttcttgcgttaccaatggattctcgtttatttattggcggcgacgccgaccgttgac
gctaattatttccgtggcggcacaccattaaaaccagggcagtatgtgcgtagtctgcgt
tccagccaatatggctatgtgaatgatccgagcgtcaaaatttcttacgacagcctgaag
gattatgtcaatactttggaacacgcagtaaacagcggtcaattaatcgcggaaaaagag
ttttattccaatgtccgtttacgtggcgcgaagcacgcccgcgagctgctgcaaaacggc
attcagtatttggaatttcgcctgttcgatttgaatccgttcgagccttatggtattgcg
ctaaacgatgcgaaattcgttcactattttattttgcttatggcgtggttggacgaagaa
tccaccgaaagtgcggtggatttaggcaaagaaaaattagcgcaggtggcgtgggaaaat
ccgttgtcgccgaccgcctttcaatcggaaggggagcgtgtgttacagcaattgctagcc
atgttgacggaaattcatgctggcgcggaaatcgcgacgatcgtaaaagagaaattggca
caatttgcggatccgacacttactcttggcgcgcgtttggttaatgccattgagcaacat
ggcggttatcaaaaattgggtgcggaactggcgattcgttacaaacagcaggcatttgag
cgtttttacgctttgtccgctttcgataatatggagctttctacccaagccttaatgttc
gatgccattcaaaaagggctgaaaattgaaattctggatgaacgggatcaattcctcagt
ctgcaattcggcgatcatttggaatatgtgaaaaacggcaacatgacttcccacgacagc
tacatttcgccgctgattatggaaaataaagtcgtgaccaaaaaagtgttggcgaaagcc
gggtttaacgtgccgcaaagtgtggaatttaccggtgtggaacaggcggttgccaattac
gcattatttgccggtcgtgccgtggtgattaaaccgaaatccaccaattacggcttaggt
atcagcattttccaacaaggtgtacatgatcgggaagattttgccaaagccattgaaatc
gcttttcgtgaagataaagaagtgatagtggaagattatttaaccggcaccgaataccgt
ttctttgtgctgggcgatgaaaccctggcggtgttattgcgcgtgccggcgaatgttatc
ggcgacggcgtgcatacggtggcggaattggtggcgcagaaaaacgatcatccgttgcgt
ggcgacggtagccgtacgccgttgaagaaaatcgctttgggcgatattgagcggttacag
ttgaaagaacagggtttgacggtggatagcgtgccggcaaaagatcagttggtgcagttg
cgcgccaattccaatatcagcaccggcggtgattctattgacatgaccgatcaaatgcac
ccaagctacaaagcactcgcggtgggcattaccaaagccatgggcgcggcagtgtgcggc
gtggatttaattattcccgatttaaccaagcctgccgaaccgaacctgcaatcctggggt
gtgattgaagccaatttcaacccgatgatgatgatgcacattttcccttacgccggacaa
tcccgcagagtgacacaaaacgtgttgaagatgttatttcctgagttgaaataa
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