KEGG   Aquifex aeolicus: aq_633
Entry
aq_633            CDS       T00013                                 
Symbol
ligA
Name
(GenBank) DNA ligase (NAD dependent)
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
aae  Aquifex aeolicus
Pathway
aae03030  DNA replication
aae03410  Base excision repair
aae03420  Nucleotide excision repair
aae03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:aae00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    aq_633 (ligA)
   03410 Base excision repair
    aq_633 (ligA)
   03420 Nucleotide excision repair
    aq_633 (ligA)
   03430 Mismatch repair
    aq_633 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:aae03032]
    aq_633 (ligA)
   03400 DNA repair and recombination proteins [BR:aae03400]
    aq_633 (ligA)
Enzymes [BR:aae01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     aq_633 (ligA)
DNA replication proteins [BR:aae03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     aq_633 (ligA)
DNA repair and recombination proteins [BR:aae03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     aq_633 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     aq_633 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     aq_633 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      aq_633 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 DNA_ligase_ZBD Nlig-Ia PTCB-BRCT HHH DUF4252 BRCT_2 Zn_ribbon_NUD DUF6085 RNA_pol_A_CTD zf-IS66
Other DBs
NCBI-ProteinID: AAC06838
UniProt: O66880
LinkDB
Position
433166..435328
AA seq 720 aa
MFTPEREKELQEKTRELLRKIKDVKVLSFEEAKKLAEDLREVIRYHDYKYYVEANPVIPD
YDYDRLFRALKEIEKKYPELITPDSPTQRVASEISGEFPTVKHYTPMLSLDNAYSEDELR
EFDRRVRQITGLEVVEYAVEPKLDGAGIALVYENDLFVRGATRGDGEYGEDITNNLKTIK
TIPLKAEFSRFGIKLAEIRGEVVIRKDEFQKLNKERMEEGLPPFANPRNAAAGSIRQKDP
KEVAKRNLEAIVYHLSYVEPPETEPPTHYESLKMLHTLGFKTLFKDTKVCKGIDEVIEYC
KEWEKKRDSYPYEIDGMVVKVNDRRLWKVLGYTSHHPRWAIAYKFKPRRAVTKLVDVVFQ
VGRTGTITPVGKLEPVELGGVTVSSVSLFNEDFIREKDIRIGDWVVVERAGDVIPYVVEV
LKEKRTGEEKPVEFPKYCPSCGSELVKLPEEVAIRCINISCPAQSVLRIKHWASRDAMDI
RGLGDATIKLLFNRGLAKDVGDLYYLKLTDILKLPGFGEKSAMNLLKAIEESKNRPLDRV
LYGLGIRYVGQTTAKKIAEIINSVWDLKDIPLEKLMRLEGIGYKVARSIKEFFNIPQNLE
VLKKLEKAGVNLAKKVKEKVADVLKGKTFVFTGTLDCCSREKAGEIVEMLGGKFSNSVTS
KTDYLVVGKDPGATKLSKAKKYGVKTITEEEFVNMIKDYVDLEKIKKEDKKEKPKIGRLF
NT seq 2163 nt   +upstreamnt  +downstreamnt
atgtttaccccagaaagggaaaaggaacttcaggaaaaaacacgggaactcctgagaaag
attaaggacgtaaaagtcctgagctttgaggaagctaaaaaactcgcggaagacctcaga
gaagtaatcaggtatcacgattacaagtactacgtcgaggcaaacccagtaattcccgat
tacgattacgacagactcttcagggctttaaaagaaatagagaaaaaataccccgagctt
atcactcccgattctcctactcagagagtggcgagcgaaataagcggagagtttcccacg
gttaaacactacacccctatgctctctctggacaacgcctactcggaagatgaactcaga
gagtttgacaggagggtaagacagattacgggattggaagtagtagagtacgcggtagag
ccaaaactggacggtgcgggtatagctcttgtttatgaaaacgatttgttcgtcaggggg
gctacgaggggcgacggtgagtacggggaagacataacgaataacctcaaaactattaaa
acaataccactaaaggcggaattttcccgtttcggaatcaaacttgcggaaatcagggga
gaagtagttataaggaaagatgaatttcaaaaattaaataaagaaagaatggaagaagga
ttgcctccgtttgccaatcccaggaatgcggctgcaggctccattaggcagaaggatcct
aaggaagttgctaagagaaatctggaagctatcgtataccacctctcttacgtagaaccc
cctgagaccgaaccgccaacccactacgaatctttgaaaatgctccatacactcggtttc
aagacgctctttaaggacacaaaagtctgcaagggcatagacgaagttatagagtactgc
aaggagtgggagaaaaagagggactcttacccttacgagatagacggaatggtcgttaag
gtgaacgacagaaggttgtggaaggttctcggttacacttcccaccatccgaggtgggct
atagcgtataagttcaagccaaggagagcggtaacaaaactcgttgacgttgtctttcag
gtgggaaggacgggaacgattacacctgtgggtaagctcgagcctgtagagctgggaggc
gttaccgtttcttctgtatctctatttaacgaagactttataagggaaaaggacatcagg
ataggtgactgggtggtagttgagagggctggagacgttataccttacgtggttgaagtc
ttaaaggaaaagagaacgggtgaagagaaacccgtggaatttccaaagtactgtccttcc
tgcggttctgagctcgtaaaacttcccgaggaagtagctataaggtgtataaacatatcc
tgccccgctcagagcgttttgaggattaaacactgggcgagcagagacgcaatggacata
agaggactgggagacgccacaataaaacttctattcaacaggggactcgcaaaggacgtg
ggagacctttactacctaaagttgacggacattttaaagcttcctggatttggagaaaaa
tccgctatgaacttactgaaggctattgaggagagcaaaaatagacctcttgatagagtc
ctttacggactcggtataaggtacgtgggacaaactacagcaaaaaaaatagccgaaatt
ataaacagtgtatgggatttaaaagacattccccttgagaagttgatgagattggaagga
atagggtacaaggtagcaaggagtataaaggagttcttcaacatacctcaaaaccttgaa
gttcttaaaaaactggaaaaggcgggtgtaaacctcgccaagaaagtcaaagaaaaagtt
gcagacgttttgaaaggaaaaactttcgttttcacgggaacgctcgattgttgttcgagg
gaaaaggcgggggagattgttgagatgctcggcggaaagttctcaaactctgtgacttcc
aaaacagattacctagtggtgggtaaagatcccggagctacaaaactcagtaaagctaag
aagtacggagtaaagactataaccgaagaggaattcgtaaacatgataaaagattacgtg
gatttggagaaaataaagaaggaggataagaaggaaaaaccgaaaataggcagactattt
tga

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