KEGG   Arvicola amphibius (Eurasian water vole): 119803862
Entry
119803862         CDS       T08327                                 
Symbol
Casp8
Name
(RefSeq) caspase-8
  KO
K04398  caspase 8 [EC:3.4.22.61]
Organism
aamp  Arvicola amphibius (Eurasian water vole)
Pathway
aamp01524  Platinum drug resistance
aamp04115  p53 signaling pathway
aamp04210  Apoptosis
aamp04215  Apoptosis - multiple species
aamp04217  Necroptosis
aamp04620  Toll-like receptor signaling pathway
aamp04621  NOD-like receptor signaling pathway
aamp04622  RIG-I-like receptor signaling pathway
aamp04623  Cytosolic DNA-sensing pathway
aamp04625  C-type lectin receptor signaling pathway
aamp04657  IL-17 signaling pathway
aamp04668  TNF signaling pathway
aamp04932  Non-alcoholic fatty liver disease
aamp04936  Alcoholic liver disease
aamp05010  Alzheimer disease
aamp05016  Huntington disease
aamp05022  Pathways of neurodegeneration - multiple diseases
aamp05132  Salmonella infection
aamp05134  Legionellosis
aamp05142  Chagas disease
aamp05145  Toxoplasmosis
aamp05152  Tuberculosis
aamp05160  Hepatitis C
aamp05161  Hepatitis B
aamp05162  Measles
aamp05163  Human cytomegalovirus infection
aamp05164  Influenza A
aamp05165  Human papillomavirus infection
aamp05167  Kaposi sarcoma-associated herpesvirus infection
aamp05168  Herpes simplex virus 1 infection
aamp05169  Epstein-Barr virus infection
aamp05170  Human immunodeficiency virus 1 infection
aamp05200  Pathways in cancer
aamp05203  Viral carcinogenesis
aamp05416  Viral myocarditis
aamp05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:aamp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    119803862 (Casp8)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    119803862 (Casp8)
   04215 Apoptosis - multiple species
    119803862 (Casp8)
   04217 Necroptosis
    119803862 (Casp8)
   04115 p53 signaling pathway
    119803862 (Casp8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    119803862 (Casp8)
   04621 NOD-like receptor signaling pathway
    119803862 (Casp8)
   04622 RIG-I-like receptor signaling pathway
    119803862 (Casp8)
   04623 Cytosolic DNA-sensing pathway
    119803862 (Casp8)
   04625 C-type lectin receptor signaling pathway
    119803862 (Casp8)
   04657 IL-17 signaling pathway
    119803862 (Casp8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    119803862 (Casp8)
   05203 Viral carcinogenesis
    119803862 (Casp8)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    119803862 (Casp8)
   05161 Hepatitis B
    119803862 (Casp8)
   05160 Hepatitis C
    119803862 (Casp8)
   05164 Influenza A
    119803862 (Casp8)
   05162 Measles
    119803862 (Casp8)
   05168 Herpes simplex virus 1 infection
    119803862 (Casp8)
   05163 Human cytomegalovirus infection
    119803862 (Casp8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    119803862 (Casp8)
   05169 Epstein-Barr virus infection
    119803862 (Casp8)
   05165 Human papillomavirus infection
    119803862 (Casp8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    119803862 (Casp8)
   05134 Legionellosis
    119803862 (Casp8)
   05152 Tuberculosis
    119803862 (Casp8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    119803862 (Casp8)
   05142 Chagas disease
    119803862 (Casp8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    119803862 (Casp8)
   05016 Huntington disease
    119803862 (Casp8)
   05022 Pathways of neurodegeneration - multiple diseases
    119803862 (Casp8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    119803862 (Casp8)
   05416 Viral myocarditis
    119803862 (Casp8)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    119803862 (Casp8)
   04932 Non-alcoholic fatty liver disease
    119803862 (Casp8)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    119803862 (Casp8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:aamp01002]
    119803862 (Casp8)
Enzymes [BR:aamp01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.61  caspase-8
     119803862 (Casp8)
Peptidases and inhibitors [BR:aamp01002]
 Cysteine peptidases
  Family C14: caspase family
   119803862 (Casp8)
SSDB
Motif
Pfam: Peptidase_C14 DED PYRIN
Other DBs
NCBI-GeneID: 119803862
NCBI-ProteinID: XP_038171228
LinkDB
Position
18:32014359..32045705
AA seq 480 aa
MDFSSCLYNIAEQLGSSEVAALKFLCLDYIPPKKQEPINDALMLFQALQEKEMLEEGNLF
FLKELLFLICRLDLLTHDLNSSKEEMKKELYDLDRAQVSAYRVMLFKLSEHVSDLELKEF
KFFLEKKIPKCKLHDNSSLLDVFVEMEKRLILGEDNFETLKSIFEYVNKSLLRYIEDFEE
SNRERRMSLEGGAEASGSFSDGQSCIRMQEMYNSLREDIDSQVSDRIYQMKSKPRGYCLI
INNNDFSKAREDVPRLCKIRDRKGTRHDEDALTDTFQKLHFEVVSHKDCTASKIREILRA
FQSMDHESKDCFICCILSHGDKGIIYGTDGKEASIRELTSYFTGSKCPSLAGKPKVFFIQ
ACQGDSFQKAVPVETDSEQDNYLDIDSSSQKNYIPDEADFLLGMATVKNCVSYRDPMRGT
WYIQSLCESLRERCPRGDDILSILTGVNYDVSNKDDRRNMGKQMPQPIFTLRKKLFFPLN
NT seq 1443 nt   +upstreamnt  +downstreamnt
atggatttcagcagctgcctttacaatattgccgaacagctgggcagtagtgaagtggcc
gccctcaagtttctgtgtttggactacataccaccgaagaaacaggagcccatcaacgat
gccctgatgctcttccaggcgctgcaggagaaggaaatgttggaggaaggcaatctgttc
ttcctgaaggagctgcttttcctcatctgtcggctggacctgctgacccacgacctaaac
agcagtaaggaggagatgaagaaagagctttatgatctagacagagctcaggtttctgcc
tacagggtaatgctctttaagctctcagaacacgtgagcgatttggagttgaaagagttt
aagtttttcttggaaaagaagatccccaaatgtaagctgcacgataactcgagcctgctg
gatgtttttgtggaaatggagaagaggctcatcctgggggaggacaactttgagaccctg
aagtcaatctttgaatatgtcaacaagagtctgctgcggtatattgaagactttgaagaa
tcaaacagagagagaagaatgagcctggaaggcggagcagaggcgtcaggctcattttcg
gacgggcagagctgcatcagaatgcaggaaatgtataactccctaagagaagacatcgac
tcccaggtatcggatagaatatatcaaatgaagagcaaacctcggggatactgtctgatc
atcaacaataacgacttcagcaaggcgcgggaggacgtacccagactctgcaagatcagg
gacaggaaaggaacaagacatgatgaagacgcgttgaccgacacctttcaaaagcttcat
tttgaggtcgtgtctcacaaagactgcacagccagtaagatccgtgagatcctaagagcc
ttccaaagcatggaccacgagagcaaagactgcttcatctgctgcatcctctcccacggg
gacaagggtatcatctacggcaccgacgggaaggaagcctccatccgtgagctgacatcg
tatttcactggttccaagtgtccttctctggctggaaaacccaaagtctttttcattcag
gcttgccaaggggatagcttccagaaagctgtacccgttgagaccgactcagagcaggac
aactacttagacattgactcatcatctcaaaagaactatattccagatgaggctgacttt
ctgctggggatggctactgtgaaaaattgtgtttcctaccgagatcccatgcgcggaacc
tggtacatccagtcactttgcgagagcctgagagaaagatgtcctcgaggtgatgatatt
ctcagcatcctgactggcgtaaactacgatgtgagcaataaagacgacaggaggaacatg
gggaagcagatgccccagcccatcttcacgctacggaagaagctgttcttccctctcaac
tga

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