Arvicola amphibius (Eurasian water vole): 119812811
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Entry
119812811 CDS
T08327
Name
(RefSeq) polyunsaturated fatty acid (12S)/(13S)-lipoxygenase, epidermal-type
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
aamp
Arvicola amphibius (Eurasian water vole)
Pathway
aamp00590
Arachidonic acid metabolism
aamp01100
Metabolic pathways
aamp01523
Antifolate resistance
aamp04726
Serotonergic synapse
aamp04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
aamp00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
119812811
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
119812811
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
119812811
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
119812811
Enzymes [BR:
aamp01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
119812811
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Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
119812811
NCBI-ProteinID:
XP_038183693
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Position
4:50680744..50687312
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AA seq
662 aa
AA seq
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MGKYTIRVVTGDSLLAGSSNLVQLWLVGEHGEADLGKRLRPMRRGETQLEIDVPVHLGRL
LLVKMHKHRGLLESDWFCKWVTVQGPGTQGEVFFPCYSWVQSNETICVSEGTALKVNDDT
QSLFRKYREQEMEDRRKLYRWGSWKEGLILPVAGSTQWDLPRNQRFMEDKDFDFSFTLAK
VLKEFAIKGTLDFVSRVQNLEDYQKIFPYGTTALAERVRESWKDDALFGYQFLNGANPML
LRRSKSLPDRLVVPPEMQDLQTQLEKELQAGTLFEADFSLLDGVKPNIIIFKQQYVTAPL
VMLKLEPDGRLLPMLIQLHPPRHGCSPPPLFLPSDPPMAWLLAKIWVRSSDFQLHQLQSH
LLRGHLMAEVISVATMRSLPSLHPIYKLLIPHFRYTMEINILARNNLVSEWGIFDLVVST
GSGGHVDILQRATACLTYRSFCPPDDLADRGLLDVKSSLYAQDALRLWEIISRYVERMVE
LFYKSDQDVKDDPELQVWCREITEIGLLRGQERGFPLSLESRAQLCRFVTMCIFTCTGQH
ASAHQGQLDWYAWIPNGPCTMRKPPPTSKDVTEKDIVDAMPTLQQARMQMTFTKFLGRRQ
PVMVALGHHTEEYFSGPEPRAVLKQFQEELAVMDKEIDVRNAGLDLPYEYLQPSMVENSV
TI
NT seq
1989 nt
NT seq
+upstream
nt +downstream
nt
atgggcaagtacacgatccgggtggtcactggagactcgcttctggcgggctccagcaac
ctggtgcagctgtggctggtgggcgagcatggggaggcggacctcgggaagcggctgcga
ccaatgcggagaggggaaacgcagttggagatcgacgtccccgtgcatctaggacgcctc
ctgctggtgaagatgcacaaacacagagggctgttggaatctgactggttctgcaagtgg
gtcactgtgcagggccctgggacccaaggagaggtctttttcccctgctacagttgggtg
cagagcaacgagacgatctgtgtgtccgagggcactgccctgaaggtaaacgacgacact
cagagcctgtttaggaagtatcgagaacaggagatggaggaccgaaggaagctgtatcgg
tggggctcctggaaggaagggttaatcctgcctgtagcagggagtacacagtgggacctc
cccaggaaccagagattcatggaagataaggattttgatttttccttcactctggctaaa
gtgttgaaggaatttgccattaaggggactttagattttgtaagtcgtgtacaaaatctg
gaagattaccaaaagatattcccatatggaactactgctctggccgagcgggttcgtgaa
tcctggaaggacgatgccctctttgggtaccagttcctcaatggtgcaaaccccatgctc
ctgaggcgctcgaagagccttccagaccgactggtggtgcctccagagatgcaagactta
cagacccagctggagaaggagctccaggctggaacgctgtttgaggctgacttctccctg
ctggatggggtcaagcccaacatcatcatctttaaacagcagtatgtgacagcccctttg
gtcatgctgaagctggagccggacggaaggctcttacccatgctcattcagctccatcca
cctcgacacggatgttccccacctccgctcttcttgccctcggatcctcccatggcctgg
ctcctggccaagatctgggttcgaagctctgatttccagctgcaccagttgcagtcacat
ctgctgagggggcatctaatggccgaggtcatctctgtggccacaatgaggagcttaccc
agcctgcatcccatatacaagctcctcatcccccactttcgctacaccatggagatcaac
atcctggcgcggaataatcttgtctctgaatgggggatttttgatctggtggtgagcaca
gggagtggaggccacgtggacattctccagagagccacagcttgtctgacttaccgctcc
ttttgccctccggatgacttggctgaccgtgggctcttggatgtgaaatcttctctctat
gcccaggatgccctcaggttgtgggagatcatcagtcggtatgtggaaaggatggtcgag
cttttctacaagagtgaccaggatgtgaaggatgaccctgagctacaggtctggtgcaga
gagatcactgagatcggactgctgaggggccaggagcgggggtttcccctatccttagag
tccagggctcagctctgccgttttgttaccatgtgcatcttcacgtgcactggtcagcat
gcttctgcccatcagggtcagctggactggtacgcctggatccccaatggcccgtgcacc
atgcggaagcccccaccgacctccaaggatgtgacagagaaggacatagtggatgcgatg
cctactctccagcaggcacggatgcagatgacattcaccaagttccttggcagacgccag
cctgtcatggtagccctggggcatcatacagaggaatatttctcaggccctgagccccgg
gctgtgctgaagcagtttcaggaggagttggctgtcatggacaaggagattgacgtcagg
aacgcaggcctggatctgccctatgagtacctccagcccagcatggtggaaaacagtgtg
actatctga
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