Arvicola amphibius (Eurasian water vole): 119825049
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Entry
119825049 CDS
T08327
Symbol
Bace2
Name
(RefSeq) beta-secretase 2
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
aamp
Arvicola amphibius (Eurasian water vole)
Pathway
aamp05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
aamp00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
119825049 (Bace2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
aamp01002
]
119825049 (Bace2)
Enzymes [BR:
aamp01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
119825049 (Bace2)
Peptidases and inhibitors [BR:
aamp01002
]
Aspartic peptidases
Family A1: pepsin family
119825049 (Bace2)
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GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
119825049
NCBI-ProteinID:
XP_038201589
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Position
10:complement(728224..809263)
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AA seq
514 aa
AA seq
DB search
MGALLRALLLPLLAQWLLRAAPALAPAPFTLPLQVAAASSHGASAIPGLGTPEIPRADGL
ALALEPAGAAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGAPHS
YIDSYFDSERSSTYHPKGFDVTVKYTQGSWTGFVGEDVVAIPKGFNSSFLVNIATIFESE
NFFLPGIKWNGILGLAYAALAKPSSSLETFFDSLVAQAKIPDIFSMQMCGAGLPVAGSGT
NGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDS
GTTLLRLPQKVFDAVVEAVARTSLIPEFSDGFWTGAQLACWTNSETPWAYFPKISIYLRD
ENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISSSKNALVIGATVMEGFYVVFDRARK
RVGFAASPCAEIAGTTVSEISGPFSTEDIASNCVPAKALNEPILWIVSYALMSVCGAILL
VLILLLLLPVRCRHAPRDPEVVNDESSLVRHRWK
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgggcgcgctgctccgagcgctcctgctcccgctgttggcgcagtggctcttgcgcgca
gcccccgctctggccccggctcccttcacgctaccccttcaggtggccgcagcctcgagc
cacggagcctcggctattcctgggctcgggactcctgagataccccgtgcagatggcctg
gcgctagctctggagccagccggggctgccgccaacttcttggctatggtggacaacctg
cagggggactccggccgcggctactacctggagatgctgatcgggaccccgccgcagaag
ctgcagattcttgtggacacgggaagcagtaacttcgctgtggcaggcgccccacattcc
tatattgactcctactttgattcggagagatccagcacataccaccccaagggctttgat
gtcactgtgaagtacacacagggaagctggactggcttcgtgggtgaggacgttgtcgcc
atcccaaaaggcttcaacagctctttcctggtcaacattgccacgatttttgagtctgag
aatttctttttgcctgggattaaatggaatggaattctcggacttgcttatgctgccttg
gccaagccatcgagttctctggagaccttctttgattccctggtggcccaagcaaagatt
ccggacattttctccatgcagatgtgtggggctggattgccagtagctggatctggtacc
aacggaggtagtcttgtcctgggtgggattgaaccaagtttgtataaaggagacatctgg
tataccccaattaaggaggaatggtactatcagatagagatcctgaaattggaaatcgga
ggccagagcctcaacctggactgtagagagtataatgcggacaaggccattgtggacagc
ggcaccacgctcctgcgcctgccccagaaggtgttcgatgcggtggtggaagctgtggca
cgcacatctctgattccagagttttctgatggcttctggacaggggcccagctggcatgc
tggacaaattctgaaacgccatgggcatatttccctaagatctctatctacctgagagat
gagaactccagtcgctccttccgaatcaccatcctaccacagctctacattcagcccatg
atgggagctggtctcaattatgaatgctatcgctttggtatctcctcctccaaaaacgca
ctggtcattggtgccaccgtgatggaggggttctacgtggtctttgacagagctcggaag
agggtgggcttcgcagcaagtccctgtgcagagatcgcagggaccacagtgtcggaaatt
tccgggcccttttccacagaagacatagccagcaactgtgtcccagcaaaggctctgaat
gagcccatcttgtggattgtgtcctatgccctgatgagtgtgtgtggagccatcctcctg
gttctgattctcctcctgctgctcccagtgcgatgccgacatgctccccgtgaccctgag
gtcgttaatgatgagtcctcactggtcagacaccgctggaaatga
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