Arvicola amphibius (Eurasian water vole): 119827826
Help
Entry
119827826 CDS
T08327
Symbol
Hsd11b1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
aamp
Arvicola amphibius (Eurasian water vole)
Pathway
aamp00140
Steroid hormone biosynthesis
aamp00980
Metabolism of xenobiotics by cytochrome P450
aamp01100
Metabolic pathways
aamp05204
Chemical carcinogenesis - DNA adducts
Module
aamp_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
aamp00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
119827826 (Hsd11b1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
119827826 (Hsd11b1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
119827826 (Hsd11b1)
Enzymes [BR:
aamp01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
119827826 (Hsd11b1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
THF_DHG_CYH_C
Pyr_redox_2
FMO-like
2-Hacid_dh_C
Pyr_redox_3
Methyltransf_25
Motif
Other DBs
NCBI-GeneID:
119827826
NCBI-ProteinID:
XP_038205664
LinkDB
All DBs
Position
12:2049289..2073323
Genome browser
AA seq
291 aa
AA seq
DB search
MAFLKKYLLPILVLFLGYYYSTVEEFRPEMLRGKKVIVTGASKGIGREMAYHLAQMGAHV
VLTARSEEGLQKVVSRCLELGAASAHYVAGTMEDMAFAEQFVLKAGKLMGGLDMLILNHI
TYFSLGFFHDDIHTVRKAMEVNFISYVVLSAAALPMLKQSSGSIAVVSSMAGKMTQPMIA
PYSASKFALDGFFSTIRQEYSLAKVNVSITLCILGLINTETAMKATSGMLMAEAAPKEEC
ALEIIKGTALRKDEVYYDKSGWVPLLLSNPGRRIMEYFSIRNYNLERFLKN
NT seq
876 nt
NT seq
+upstream
nt +downstream
nt
atggcattcctgaaaaaatacctgctccccattctggtgctcttcttgggctactactat
tctacagtagaagagttcagacccgaaatgctccgagggaaaaaagtgattgtcacgggg
gccagcaaagggatcggaagagaaatggcctatcacctggcgcagatgggagcccatgtg
gtactgaccgcgaggtcagaggaaggtctccagaaggtggtgtctcgctgccttgaactc
ggagcagcctctgcccactacgtggctggcaccatggaagacatggcgtttgcagagcag
tttgtcctcaaagcgggaaagctcatgggtggattggacatgctcattctcaaccacatc
acttacttctctctgggtttcttccacgatgacatccacactgtgcgcaaagccatggag
gtcaacttcatcagctacgtggtcctgagtgccgccgccttgcccatgctgaagcagagc
agcggcagcattgctgtggtctcctccatggctgggaaaatgacccagcctatgattgct
ccctactctgcaagcaagtttgctctggatgggtttttttccaccatccgacaagaatac
tcactagccaaggtcaacgtctccatcactctctgtatccttggcctcataaacacagaa
acagccatgaaggcaacctctggtatgctcatggccgaagccgcccccaaggaggaatgt
gctctggagatcatcaagggaacggctctgcggaaagatgaggtgtactacgacaagtcg
ggctgggtccctctcctgctaagcaacccaggaaggaggatcatggaatatttttcaata
aggaattataacttggagagatttttaaaaaactag
DBGET
integrated database retrieval system
