Aggregatibacter actinomycetemcomitans D7S-1: D7S_00314
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Entry
D7S_00314 CDS
T02046
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
aan
Aggregatibacter actinomycetemcomitans D7S-1
Pathway
aan00010
Glycolysis / Gluconeogenesis
aan00020
Citrate cycle (TCA cycle)
aan00620
Pyruvate metabolism
aan00785
Lipoic acid metabolism
aan01100
Metabolic pathways
aan01110
Biosynthesis of secondary metabolites
aan01120
Microbial metabolism in diverse environments
aan01200
Carbon metabolism
aan01210
2-Oxocarboxylic acid metabolism
Module
aan_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
aan00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
D7S_00314 (aceE)
00020 Citrate cycle (TCA cycle)
D7S_00314 (aceE)
00620 Pyruvate metabolism
D7S_00314 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
D7S_00314 (aceE)
Enzymes [BR:
aan01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
D7S_00314 (aceE)
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Paralog
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AFI86176
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Position
complement(312430..315090)
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AA seq
886 aa
AA seq
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MSELLKNDVDPIETNDWLAAIDSLIREEGVERAQFIIDQVMQQARIGGVSLPTGITTDYV
NTIPVSEQPEYPGNLDIERRIRSYVRWNAVMMVLRGQKKDLDLGGHLSTFQSAATVYEVC
FNHFFKATTEKNGGDLVFFQGHAAPGMYARAFLEGRLTEDQLDNFRQEVHGKGLSSYPHP
KLMPDFWQFSTVSMGLGPVNAIYQARFLKYLENRGLKDTADQKVYAFLGDGEMDEIESKG
ALTFAAREHLDNLIFVISCNLQRLDGPVNGNGKIVQELEGLFVGAGWEVIKVMWGSGWDK
LFAKDTTGKLTQLMMEVVDGDYLTFKSKKIGAYVREHFFGRYPETAALVADMTDDEIWAL
RRGGHDSKKVFAAFKKAQTAGKPVVILVHSVKGYKISEAESKNTAHQSKKMSMDSLKAYR
DYFHIPVKDEDLEKLPYMTFPEGSDEYNYLHQHRKALQGYLPARQPKFDVEFKVPELSEF
APLLGAQPRPISTTMAFVRFLNTLLKDKNIGKNIVPIVADEARTFGMEGLFRQVGIYNPH
GQNYVPSDRDLVAYYREAKDGQVLQEGINELGATSSWLAAATSYSISNVPMIPFFIYYSM
FGFQRVGDLLWAAGDQLARGFMIGGTSGRTTLNGEGLQHEDGHSHIQSLIIPNCVSYDPA
FAYEVAVIMQDGIHRMYGEKQEDVFYYITTLNEIYDQPAMPAGAEEGIRKGLYKFESVEG
KGKGAVQLLGSGAILRHVREAAQILAKDYGVSSDVYSAPSFTEAAREGADAVRWNMLHPT
ETPRVPYVAQVMNDKPVVAATDYMKLFAEQIRAYVPSKHYHVLGTDGFGRSDSRENLRDH
FEVDAHHVVVAALNVLAQEGSVDKKVVVEAIAKYGIDPERLNPLYA
NT seq
2661 nt
NT seq
+upstream
nt +downstream
nt
atgtcagaattgttaaaaaatgacgtagatccgatcgaaactaacgattggttggcagca
attgattcgttaattcgtgaagaaggtgttgagcgtgcgcagttcattattgatcaagtg
atgcagcaagctcgtattggcggcgtttctttgccgacagggattactacagattacgtg
aatacgatcccggtttctgaacagcccgagtatccgggaaatttagacattgagcgtcgc
attcgttcttatgtccgctggaatgctgtgatgatggtgttgcgcggtcagaaaaaagac
cttgatttaggcggtcacttatctactttccaatctgctgcaacggtttatgaagtttgt
tttaatcatttcttcaaagccacaactgagaaaaatggcggcgatttggttttcttccaa
ggtcacgctgcaccgggtatgtatgcgcgcgcattcctagaaggtcgtttgaccgaagac
caattagacaatttccgtcaagaagtgcacggcaaaggtttgtcttcttatccgcatccg
aaattaatgcctgatttttggcaattctcaacagtatctatgggtttaggtccggtcaat
gcgatttatcaagcccgtttcttaaaatacttggaaaatcgcggtttgaaagatacggct
gatcaaaaagtgtatgctttcctgggcgatggcgaaatggatgaaattgaatctaaaggt
gcattgacatttgccgcccgtgaacatttggataacttaatttttgtgatttcctgtaac
ttacaacgcttagacggaccggtaaacggtaacggtaaaatcgttcaagaattagaaggt
ttattcgtcggcgcaggttgggaagtgattaaagtcatgtggggtagcggttgggataaa
ttattcgccaaagacaccacaggcaaattaacccaattaatgatggaagtggttgacggg
gactacctgactttcaaatctaaaaagattggtgcctatgtgcgcgagcatttcttcggt
cgttaccctgaaactgccgctttagttgccgacatgacagatgatgaaatctgggcgtta
agacgcggtggtcatgattcgaagaaagtttttgccgcattcaagaaagcgcaaacagcg
ggcaaaccggtggtgattttagtgcattccgtgaaagggtataaaatttccgaagcagaa
agtaaaaacactgcgcaccaatccaaaaaaatgtctatggatagccttaaagcctaccgt
gattacttccatattccggtgaaagacgaagatttggaaaaactgccttacatgaccttc
cctgaaggttcggacgagtacaattacttgcaccaacaccgtaaagcattacaaggatat
ttaccggcgcgtcaaccgaaatttgacgttgaatttaaggtgcctgagcttagcgaattc
gcaccgttgttaggcgcacaaccacgtccgatttcaactacaatggcattcgtccgtttc
ctaaataccttattgaaagacaaaaatatcggtaaaaacattgttccgatcgtcgcggat
gaagcccgtactttcggtatggaaggcttgttccgtcaagtaggtatttataacccgcac
ggtcaaaactatgttccttcagatcgcgacctcgtggcgtactatcgtgaagcgaaagac
ggtcaggtattgcaagaaggtatcaacgaattaggcgcgacatcttcctggttggctgcg
gcaacctcttattccatcagtaatgtgccgatgattccgttctttatttattactctatg
ttcggcttccaacgtgtgggcgacttattgtgggcagcgggcgaccaattggcgcgcggc
ttcatgatcggcggtacatcaggccgtacgacattaaacggtgaaggtttacaacacgaa
gacggtcacagccatattcaatccttaatcattccgaactgcgtgtcttatgatccggca
ttcgcttatgaagtggcggtaataatgcaggatggtatccaccgtatgtacggcgaaaaa
caagaagatgtgttctattacatcaccaccttaaacgaaatttatgaccaaccggcaatg
cctgccggtgcggaagagggtattcgtaaaggtctgtataaatttgaaagcgttgaaggc
aaaggtaaaggcgcggtgcaattattaggttccggcgcgattttacgtcatgttcgcgaa
gcggctcaaatcttagcgaaagattacggcgtcagttctgatgtttatagcgcgccgtct
ttcactgaagcggctcgcgaaggtgccgacgcggtacgttggaatatgttacacccaacc
gaaacgccacgtgtgccatacgttgcgcaagtgatgaacgacaaaccggtagtggcggca
acggactacatgaaactgttcgccgagcaaattcgcgcctatgtgccgtctaaacactac
catgtgttaggtaccgacggtttcggtcgttccgatagccgtgaaaacttacgcgatcac
tttgaagtcgatgcgcaccacgtcgttgttgcggcattaaacgtgttggcgcaagaaggc
tcggttgataagaaagttgttgtcgaagcaatcgctaaatacggtatcgatcctgaaaga
ttgaacccgctatacgcataa
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