Entry |
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Symbol |
aceE
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Name |
pyruvate dehydrogenase E1 component [EC: 1.2.4.1]
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Pathway |
map01110 | Biosynthesis of secondary metabolites |
map01120 | Microbial metabolism in diverse environments |
map01210 | 2-Oxocarboxylic acid metabolism |
|
Module |
M00307 | Pyruvate oxidation, pyruvate => acetyl-CoA |
|
Reaction |
R00014 | pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating) |
R00209 | pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating) |
R01699 | pyruvate:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating) |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
K00163 aceE; pyruvate dehydrogenase E1 component
00020 Citrate cycle (TCA cycle)
K00163 aceE; pyruvate dehydrogenase E1 component
00620 Pyruvate metabolism
K00163 aceE; pyruvate dehydrogenase E1 component
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
K00163 aceE; pyruvate dehydrogenase E1 component
Enzymes [BR:ko01000]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
K00163 aceE; pyruvate dehydrogenase E1 component
Enzymes of 2-oxocarboxylic acid metabolism [br01601.html]
2-Oxoacid oxidizing enzymes
K00163
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Other DBs |
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Genes |
» show all
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Reference |
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Authors |
Tian J, Bryk R, Shi S, Erdjument-Bromage H, Tempst P, Nathan C |
Title |
Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes. |
Journal |
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Sequence |
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Reference |
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Authors |
Reed LJ, Pettit FH, Eley MH, Hamilton L, Collins JH, Oliver RM. |
Title |
Reconstitution of the Escherichia coli pyruvate dehydrogenase complex. |
Journal |
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Sequence |
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LinkDB |
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