Aggregatibacter actinomycetemcomitans D11S-1: D11S_1236
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Entry
D11S_1236 CDS
T00993
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
aat
Aggregatibacter actinomycetemcomitans D11S-1
Pathway
aat00010
Glycolysis / Gluconeogenesis
aat00020
Citrate cycle (TCA cycle)
aat00620
Pyruvate metabolism
aat00785
Lipoic acid metabolism
aat01100
Metabolic pathways
aat01110
Biosynthesis of secondary metabolites
aat01120
Microbial metabolism in diverse environments
aat01200
Carbon metabolism
aat01210
2-Oxocarboxylic acid metabolism
Module
aat_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
aat00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
D11S_1236 (aceE)
00020 Citrate cycle (TCA cycle)
D11S_1236 (aceE)
00620 Pyruvate metabolism
D11S_1236 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
D11S_1236 (aceE)
Enzymes [BR:
aat01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
D11S_1236 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ACX82618
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Position
1158319..1160976
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AA seq
885 aa
AA seq
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MSELLKNDVDPIETNDWLAAIDSLIREEGVERAQFIIDQVMQQARIGGVSLPTGITTDYV
NTIPVSEQPEYPGNLDIERRIRSYVRWNAVMMVLRGQKKDLDLGGHLSTFQSAATVYEVC
FNHFFKAATEKNGGDLVFFQGHAAPGMYARAFLEGRLTEDQLDNFRQEVHGKGLSSYPHP
KLMPDFWQFSTVSMGLGPVNAIYQARFLKYLENRGLKDTADQKVYAFLGDGEMDEIESKG
ALTFAAREHLDNLIFVISCNLQRLDGPVNGNGKIVQELEGLFVGAGWEVIKVMWGSGWDK
LFAKDTTGKLTQLMMEVVDGDYLTFKSKDGAYVREHFFGRYPETAALVADMTDDEIWALR
RGGHDSKKVFAAFKKAQTAGKPVVILAHSVKGYKISEAESKNTAHQSKKMSMDSLKAYRD
YFHIPVKDEDLEKLPYMTFPEGSDEYNYLHQHRKALQGYLPARQPKFDVEFKVPELSEFA
PLLGAQPRPISTTMAFVRFLNTLLKDKNIGKNIVPIVADEARTFGMEGLFRQVGIYNPHG
QNYVPSDRDLVAYYREAKDGQVLQEGINELGATSSWLAAATSYSISNVPMIPFFIYYSMF
GFQRVGDLLWAAGDQLARGFMIGGTSGRTTLNGEGLQHEDGHSHIQSLIIPNCVSYDPAF
AYEVAVIMQDGIHRMYGEKQEDVFYYITTLNEIYDQPAMPAGAEEGIRKGLYKFESVEGK
GKGAVQLLGSGAILRHVREAAQILAKDYGVSSDVYSAPSFTEAAREGADAVRWNMLHPTE
TPRVPYVAQVMNDKPAVAATDYMKLFAEQIRAYVPSKHYHVLGTDGFGRSDSRENLRDHF
EVDAHHVVVAALNVLAQEGSVDKKVVVEAIAKYGIDPERLNPLYA
NT seq
2658 nt
NT seq
+upstream
nt +downstream
nt
atgtcagaattgttaaaaaatgacgtagatccgatcgaaactaacgattggttggcagca
attgattcgttaattcgtgaagaaggtgttgagcgtgcgcagttcattattgatcaagtg
atgcagcaagctcgtattggcggcgtttctttgccgacagggattactacagattacgtg
aatacgatcccggtttctgaacagcccgagtatccgggaaatttagacattgagcgtcgt
attcgttcttatgtccgctggaatgctgtgatgatggtgttgcgcggtcagaaaaaagac
cttgatttaggcggtcacttatctactttccaatctgctgcaacggtttatgaagtttgt
tttaatcatttcttcaaagccgcaaccgagaaaaatggcggcgatttggttttcttccaa
ggtcacgctgcaccgggtatgtatgcgcgcgcattcctagaaggtcgtttgaccgaagac
caattagacaatttccgtcaagaagtgcacggcaaaggtttgtcttcttatccgcatccg
aaattaatgcctgatttttggcaattctcaacagtatctatgggtttaggtccggtcaat
gcgatttatcaagcccgtttcttaaaatacttggaaaatcgcggtttgaaagatacggct
gatcaaaaagtgtatgctttcctgggcgatggcgaaatggatgaaattgaatctaaaggt
gcattgacatttgccgcccgtgagcatttggataacttaatttttgtgatttcctgtaac
ttacaacgcttagacggaccggtaaacggtaacggtaaaatcgttcaagaattagaaggt
ttattcgtcggcgcaggttgggaagtgattaaagtcatgtggggtagcggttgggataaa
ttattcgccaaagacaccactggtaaattaacccaattaatgatggaagtggttgacggg
gactacctgactttcaaatcaaaagatggtgcctatgtgcgcgagcatttcttcggtcgt
taccctgaaactgccgctttagttgccgacatgacagatgatgaaatctgggcgttaaga
cgcggtggtcatgattcgaagaaagtttttgccgcattcaagaaagcgcaaacagcgggc
aaaccggtggtgattttagcgcattccgtgaaagggtataaaatttccgaagcagaaagt
aaaaacactgcgcaccaatccaaaaaaatgtctatggatagccttaaagcctaccgtgat
tacttccatattccggtgaaagacgaagatttggaaaaactgccttacatgaccttccct
gaaggttcggacgagtacaattacttgcaccaacaccgtaaagcattacaaggatattta
ccggcgcgtcaaccgaaatttgacgttgaatttaaggtgcctgagcttagcgaattcgca
ccgttgttaggcgcacaaccacgtccgatttcaactacaatggcattcgtccgtttccta
aataccttattgaaagacaaaaatatcggtaaaaacattgttccgatcgtcgcggatgaa
gcccgtactttcggtatggaaggcttgttccgtcaagtaggtatttataacccgcacggt
caaaactatgttccttcagatcgcgacctcgtggcgtactatcgtgaagcgaaagacggt
caggtattgcaagaaggtatcaacgaattaggcgcgacatcttcctggttggctgcggca
acctcttattccatcagtaatgtgccgatgattccgttctttatttattactctatgttc
ggcttccaacgtgtgggcgacttattgtgggcagcgggcgaccaattggcgcgcggcttc
atgatcggcggtacatcaggccgtacgacattaaacggtgaaggtttacaacacgaagac
ggtcacagccatattcaatccttaatcattccgaactgcgtgtcttatgatccggcattc
gcttatgaagtggcggtaataatgcaggatggtatccaccgtatgtacggcgaaaaacaa
gaagatgtgttctattacatcaccaccttaaacgaaatttatgaccaaccggcaatgcct
gccggtgcggaagagggtattcgtaaaggtctgtataaatttgaaagcgttgaaggcaaa
ggtaaaggcgcggtgcaattattaggttccggcgcgattttacgtcatgttcgcgaagcg
gctcaaatcttagcgaaagattacggcgtcagttctgatgtttatagcgcgccgtctttc
actgaagcggctcgcgaaggtgccgacgcggtacgttggaatatgttacacccaaccgaa
acgccacgtgtgccatacgttgcgcaagtgatgaacgacaaaccggcagtggcggcaacg
gactacatgaaactgttcgccgagcaaattcgcgcctatgtgccgtctaaacactaccat
gtgttaggtaccgacggtttcggtcgttccgatagccgtgaaaacttacgcgatcacttt
gaagtcgatgcgcaccacgtcgttgttgcggcattaaacgtgttggcgcaagaaggttcg
gttgataagaaagttgttgtcgaagcaatcgctaaatacggtatcgatcctgaaagattg
aacccgctatacgcataa
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