Malaciobacter canalis: ACAN_0183
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Entry
ACAN_0183 CDS
T06502
Symbol
metH
Name
(GenBank) cobalamin-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
acaa
Malaciobacter canalis
Pathway
acaa00270
Cysteine and methionine metabolism
acaa00450
Selenocompound metabolism
acaa00670
One carbon pool by folate
acaa01100
Metabolic pathways
acaa01110
Biosynthesis of secondary metabolites
acaa01230
Biosynthesis of amino acids
acaa04981
Folate transport and metabolism
Module
acaa_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
acaa00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
ACAN_0183 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
ACAN_0183 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
ACAN_0183 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
ACAN_0183 (metH)
04980 Cobalamin transport and metabolism
ACAN_0183 (metH)
Enzymes [BR:
acaa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
ACAN_0183 (metH)
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Ortholog
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GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
OKR_DC_1_N
Motif
Other DBs
NCBI-ProteinID:
QEE31719
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All DBs
Position
189105..192584
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AA seq
1159 aa
AA seq
DB search
MREKIEEIIKNRVLVIDGAMGTQLQLADIKDENWFFENKNLEGCNELLNFTAPDVIKGIY
NAYAKADANLISTNTFGSMPWVLDEYGIGHMSYELSKIGASLAKEICQEYQSEDKPRYVL
GSIGPGTKLPSLAHIEYDEMYEGYKTMAKGLVDGGVDIFLLETCQDPLQIKTALHALQDV
ASHIPIMVSVTIELSGTMLIGTDASTIATILEPFNILSLGFNCGTGPKQVLKHVKTLSEV
SKFPISVHANAGLPQNKGGYTYYPMGPKEFVQLQEKFLDIDGVAFLGGCCGTTPQHIKAL
ADAVKDKTVKKPTGTHEASLASLFNSVALRQESSALLIGERSNATGSKAFRELLKAEDYE
GTLSVGQQQVRAGAHVIDVSVGFAGRDESKDMHKVISLYTQKIPLPLMPDSTQIKALEVA
LKKIGGRPIINSVNLEDGEEKFDEVCKLAKRFGAALVCLVIDEVGMAKTSQRKVEVAQRI
YDLAVNRHGFRPEDLVFDMLVFTVGSGDDEYRTAAIETIEAIKEFQKRHPNVGTTLGLSN
ISFGLDSKARVYLNSMFLHYCVQAGLTSAIVNVKHILPINKITQEDKKACDDLLFNNQKD
GDPLFKFIDHFSNLEEQEDQSDEEFQKLEPIEKVKKLLLDGDKERMLPLVEELRHEIKPE
IIVNEWLIDGMKIIGELFGSGQMQLPFVLQSAETMKATVDSLNPYLPKEDKASETVLVLG
TVKGDVHDVGKNLVDIILSNNGFKVINIGIKADINDFVIAVREHKAQAIGMSGLLVKSTA
VMKENLEELQRQGIDIPVLLGGAALTKSFINDFCRPIYDGPIFYCRDAFDGVVSMKRIED
GDQNNTALAADLIQVKDTSSKKEEKEIIIPPYEDIKLPSKAEFTFPPFWGRQVKTSKDID
NELVFKWINHRVLFRQRWGYKRAGQKTEDFIKHEEEVVKPLYEKLKEELIQKKVFEPISI
QAYYPCMSYDNKLYIFDYEKYGFNSLDEAKKVPNLDEAIKVLEFPRQKRKPHRCISDFFA
NDRLDVVGFTLASAGLKITSYERELYDQGKFSEYFQVHGLGVELAESLAEVIHKQIRLDL
DIVPKEGPTLYDVQMKQYVGCRYSPGYAACPELSQNRDFFDLLNPEEFGITLSETFQMDP
EQTTCAIVVPHHEANYYNI
NT seq
3480 nt
NT seq
+upstream
nt +downstream
nt
atgagagaaaaaatcgaagaaattataaaaaatagggttttagtaatagatggagctatg
ggaacacagcttcaacttgctgatataaaagatgaaaattggttttttgaaaataaaaat
ttagaaggatgcaatgagttattaaattttactgcacctgatgtaattaaaggtatttat
aatgcttatgcaaaagctgatgcaaacttaataagtacaaatacctttggttctatgcca
tgggtacttgatgagtatggtattgggcatatgtcttatgaactttctaaaataggtgca
agtttggcaaaagaaatttgccaagagtatcaaagtgaagataaaccaagatatgtttta
ggttcaataggaccaggaactaaactaccatcattggctcatattgaatatgatgagatg
tatgaaggatataaaacaatggcaaaaggtttagttgatggaggagtagatatatttctt
cttgaaacttgccaagatccacttcaaataaaaacagcacttcatgcccttcaagatgta
gcttcacatataccaattatggtctctgttactattgaacttagtggaacaatgctaata
ggaactgatgcttctactattgcaactattttagaaccttttaatatattatctttaggt
tttaattgtggtacaggaccaaaacaagtacttaagcatgtaaaaacattaagtgaagta
tcaaaattccctatatctgttcatgcaaatgcaggcttacctcaaaataaaggtggatat
acttattatccaatgggacctaaagagtttgttcaattacaagaaaagtttttagatatt
gatggagttgcttttctaggtggatgttgtggaactactcctcaacacataaaagcatta
gcagatgcagttaaagataaaactgtaaaaaaaccaacaggaactcatgaagcttctctt
gcttctttatttaatagtgttgctttaagacaagagtcatctgctttgttaattggagaa
agaagtaatgcaacaggaagtaaagcttttagagaattactaaaagctgaagattatgaa
ggtactttaagtgtaggacaacaacaagtaagagcaggagcacatgtaattgatgtttct
gttggctttgctggacgagatgaaagtaaagatatgcataaagttatatctttatatact
caaaaaattccattgcctcttatgcctgattcaactcaaataaaagccttagaagtagca
ctaaaaaaaatcggtggaagacctattattaattctgtaaatcttgaagatggtgaagaa
aagtttgatgaggtttgtaaattagcaaaaagatttggtgcagcattagtttgtttagta
attgatgaagttggaatggctaaaactagccaaagaaaagtagaagttgcccaaagaata
tatgatttagcagtaaatagacatggctttagacctgaagatttagtttttgatatgctt
gtatttacagtaggttctggagatgatgagtatagaactgctgctattgaaacaattgaa
gcaataaaagagtttcaaaaaaggcatccaaatgttggaacaacattaggtttatcaaat
atttcatttggattagattcaaaagccagagtttatttaaactctatgtttttacattat
tgtgtacaagctggacttacaagtgcaattgtaaatgttaaacatatactaccaataaat
aagattacacaagaagataaaaaagcttgtgatgatttactttttaataatcaaaaagat
ggtgacccactatttaaatttattgaccacttttcaaatttagaagaacaagaagatcaa
agtgatgaagagtttcaaaaattagaaccaatagaaaaagttaaaaaactacttttagat
ggtgataaagaaagaatgcttcctttagttgaggaattaaggcatgagattaaaccagaa
ataattgtaaatgaatggctaattgatggaatgaaaataattggtgagttatttggaagt
gggcaaatgcagttaccatttgtacttcaaagtgcagaaacaatgaaagctacagttgat
agtttaaacccttatttaccaaaagaagataaagcaagtgaaacagttctggttcttgga
acggttaaaggggatgttcatgatgtaggtaaaaatcttgttgatattattttaagtaat
aatggttttaaagtcataaatattggtattaaagcagatataaatgactttgtcattgct
gtacgcgaacataaagcacaagcaataggaatgagtggacttttagttaaaagtacagca
gtgatgaaagaaaacttagaagagttacaaagacaaggtattgatattcctgtattatta
ggtggtgctgctttaaccaaatcatttattaatgatttttgtagacctatttatgatgga
ccaattttttattgtagggatgcttttgatggagtagtatctatgaaaagaatagaagat
ggtgaccaaaataatacagcattagctgctgatttaattcaagtaaaagatacaagttct
aaaaaagaagaaaaagagattattattccaccttatgaagatataaaacttccaagtaaa
gctgaatttacttttccaccattttggggacgtcaggtaaaaacatctaaagatatagat
aatgaattggtatttaaatggataaatcatagggtactgtttagacaaagatggggatat
aaaagagctggacaaaaaacagaagattttataaaacatgaagaagaagtagttaagcct
ttgtatgaaaaattaaaagaagaattaattcaaaaaaaggtttttgaaccaatttcaata
caagcatattacccttgtatgtcatatgataataaactatatatatttgattatgaaaaa
tatggatttaactcattagatgaagcaaagaaagttccaaacttagatgaagcaataaaa
gtactagagtttccaagacaaaaaagaaaaccacatagatgtatatctgatttttttgca
aatgatagattagatgtggttggatttactcttgcaagtgctggattaaaaattacatca
tatgaaagagagttatatgatcaaggaaaatttagtgaatattttcaagtacatggatta
ggagtagaattagcagaatctttagcagaagtaattcataagcaaattagacttgattta
gatatagttccaaaggaaggaccaactttatatgatgttcaaatgaaacaatatgttggt
tgtagatactctcctggctatgctgcttgtcctgaacttagtcaaaatagagactttttt
gatttattgaaccctgaagagtttggaattactctaagtgaaacttttcaaatggatcct
gaacaaacaacttgtgctatagttgtgcctcatcacgaagctaattactataatatttag
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