Acanthamoeba castellanii: ACA1_256390
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Entry
ACA1_256390 CDS
T02667
Name
(RefSeq) histidinol dehydrogenase
KO
K14152
phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:
3.6.1.31
3.5.4.19
1.1.1.23
]
Organism
acan
Acanthamoeba castellanii
Pathway
acan00340
Histidine metabolism
acan01100
Metabolic pathways
acan01110
Biosynthesis of secondary metabolites
acan01230
Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:
acan00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
ACA1_256390
Enzymes [BR:
acan01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.23 histidinol dehydrogenase
ACA1_256390
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.19 phosphoribosyl-AMP cyclohydrolase
ACA1_256390
3.6 Acting on acid anhydrides
3.6.1 In phosphorus-containing anhydrides
3.6.1.31 phosphoribosyl-ATP diphosphatase
ACA1_256390
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Histidinol_dh
His_biosynth
PRA-CH
HisG
PRA-PH
HisG_C
DHO_dh
GATase
Dus
NMO
TMP-TENI
ThiG
PcrB
Trp_syntA
IMPDH
G3P_antiterm
MazG
GATase_3
BtpA
FMN_dh
Motif
Other DBs
NCBI-GeneID:
14911956
NCBI-ProteinID:
XP_004333513
UniProt:
L8GEH2
LinkDB
All DBs
Position
Unknown
AA seq
1682 aa
AA seq
DB search
MDAPRADVVIVETGVGNLGSMSAVLLRSGATSVKLTTDPSLVRAATHVVLPGVGSFGSAM
DFLSKADGLIAALKDRIANNQPTLCVCVGLQVLAAISEESPGANGFDLLDGAAILKFPSS
VRVPQQCWNQVVVEDGCKLLKSGCAYFSNSYCLRSRPLDWSAAYSQHGIKFIAALERGNV
VATQFHPELSGRYGTELIQRWLGTEHTGPVVEPALPTASPQFSSSSALRRVIPCLDVKSG
RVVKGIQFQGLRDAGDPVELALAYQEQGADEIVFLDISATDEERKTAVEVVKRVRQSLRV
PLTVGGGISSLADAHSLLMAGADKVSVNSAAVRDPTLISSLATCFGSQCVVCAIDATQKA
DKSGWDVLVRSGKESTGRDVVEWAKEAVLRGAGEILLTSFDRDGTRSGYDTALLKAVADA
VNVPVIASGGASTAHHMVDAFKAGADAVLAASIFHNGETTVAKIKQQLAAEGVSVRKPEG
PAGGQRLECEATFNRQCLVPSIDLMNGHAVQLVGGDPANKKLDAGDPVPLAEQFKLVGEI
AVVDLDAALGRGDNAETIKKLLTVAPCRVGGGIRTVDKALEWLNAGAAKVVIGTAAKPDF
LRQLPRERVVVALDARHGEVVVEGWQTKTGKNVKDCIRDLVEYAGGFLITFVEREGRLAG
IDIPAIEELVAEVQKTPFARSTQITIAGGITTEADLAALDALGVEGQVGMALYTGRMDLG
DSVGALLRSDRPDGLFPTVVADERGAVLGMAYSNRETLKLAIKEKKGIYYSRKRGVWRKG
ETSGAMQQLLKVDVDCDRDTLLFTVRQSGQGFCHRASYNCFGEGERGLSGLMRTLASRKQ
SAPEGSYTKRLFDDPTLLKAKLLEEATELADAEGKEHVANEAADLLYFALVACTKAGVTL
SDVEHVLEARSLKVARRPGHAKQPFLNLVNKQQQETAAAAKAKQVESEKSAAKESEEKEV
ALKRLQIAEVWDLRRDVVDKKTREIVEEILNDVRDKGEEALVRQSVRLGDLKSKEEPYLR
SQEDMKAAYLSLTPDQQSLLQRTADRVRAFAVAQKASIQSVQVPIPGGQAGHTVAPVDVA
GCYAPGGRYPLPSSVLMTAITAKVAGCKQVLVASPNPAPVTLAAAYVAGADSLLAVGGAQ
AIAAFAYGIPGKIPSCDAIVGPGNKFVTAAKSLIAGRVAIDMLAGPSECLVLADGTAHPD
VVAADLLAQAEHDVAAVPILVAYDEETVRRVEQEVEAQLATLPTAAIARAAFSNGFAVIV
ANEEEAITVCDKLAPEHLEVHTANAEELSRKLNHYGALFVGNNSAEVFGDYGAGPNHTLP
TSGTGRSFGGLSVMSFLRVRTWLNIDDLKSQPAQQLVQDSVDLALLEGLHGHARSAQKRL
VPKDQVTAASSSAVVPIPAVFGSPREPVVINFALPKGRMMDNVVTLLKDAGISINVGGRN
LRPTINLPGWTVKLLKPRNVVEMIHHGTRDELGADDVVPYFDTGLDPVRVVVAAPEKLLV
DGQLPKRHMRLATEYVALAEKWVKAHGVDAEIYKTFGSTEVFPPDDAEIIVDNTATGTTL
RANQLAIVDEITKSSTFLCINRTALEDPRKHAALDEFVILLQSALNAREKALIEFNVEKS
CLESVIAGLPSMKRPTISTLYGDEGFAVRSVIPRKALVSLVPWIKANGGSDVIVTEIKQV
IV
NT seq
5049 nt
NT seq
+upstream
nt +downstream
nt
atggacgcaccacgagctgatgtggtcatagtggagactggggtgggaaacctgggttcg
atgtcggcggttctgctgcgaagcggcgccacctcggtgaagctcaccaccgacccttcc
ctcgtccgggccgccactcacgtggtcctccccggcgtgggttcgtttggcagcgcgatg
gacttcctgtcgaaggccgacggcctgatcgctgccctcaaagaccgcatcgccaacaac
cagcccacgctctgcgtttgcgtcggacttcaggtgttggctgccatcagcgaggagagc
cctggtgccaatggcttcgaccttctcgacggcgcggccatccttaagttcccttcgtct
gtgcgcgttcctcagcagtgctggaatcaagtggtcgttgaggatggatgcaaactgctt
aagagcggctgtgcctacttcagcaactcctactgcctccgctcgcgcccgctggactgg
tccgcggcctactcgcaacacggaatcaagttcatcgcggcgcttgagcggggcaacgtg
gtggccacccagttccaccccgagctctcgggccgatacggcactgagctcatccagcgc
tggctgggtaccgagcacaccggacccgtggtcgagcccgctcttcctacggcctcgccg
cagttctcctcctcgtccgctctgcgacgcgtcatcccgtgcctcgacgtcaagagcgga
cgcgtcgtcaagggcattcaattccagggtctgcgcgatgccggtgacccggtggagctc
gccctggcctatcaagagcagggcgccgacgaaattgtattcctcgacatttctgctact
gacgaggagcgcaagacggccgtggaggtcgtcaagcgcgttcgtcagtccctgcgtgtg
cctctcaccgtcggcggcggcatctcgtccctggccgacgctcacagccttctcatggcc
ggcgcagacaaggtctccgtaaacagtgccgccgtgcgtgaccctacgctcatctcctcg
ctggccacctgcttcggctcccagtgcgtcgtgtgcgccatcgacgccacccaaaaggcc
gacaagagcgggtgggacgtgctggtgcgctcaggcaaggagagcaccgggcgtgacgtg
gtcgaatgggccaaggaggccgtgctccgcggcgccggcgagatcctgctcacctccttc
gacagggacgggacgcggtcgggctatgatacggctctgctgaaggccgtggccgacgcg
gtcaatgtgccggtcatcgcctctggtggtgcctccaccgcccaccacatggtcgacgcc
ttcaaggcgggcgccgatgcggtgctggcggcgtcgatcttccacaacggcgagacgacg
gtggccaagatcaagcagcagctggccgctgagggcgtgagcgtgcgcaagcccgaggga
cccgctggcggccagcgcctcgagtgcgaggccacgttcaacaggcagtgcctggtcccc
tcgatcgacctcatgaacggccacgccgtccagctggtcggcggcgaccccgccaacaag
aagctcgacgccggcgacccggtgccgctcgccgagcagttcaagctcgtcggcgagatt
gcggtggtggacctcgacgccgcgctcggccgcggcgacaacgccgagaccatcaagaag
ctcctgaccgtcgcgccctgccgcgttggcggcggcattcgaaccgtcgacaaggctctg
gagtggctaaacgctggcgctgccaaggtggtgatcggcacggccgccaagcccgacttc
ctgcggcagctgcccagggagcgcgtggtggtcgcgctggacgccaggcacggcgaggtc
gtcgtcgagggctggcagaccaagaccggcaagaatgtgaaggattgcattcgcgatctg
gtggagtacgccggcggtttcctgatcaccttcgtcgagcgcgagggccgcctggccgga
atcgacatccccgccatcgaggagcttgttgcggaggtgcaaaagacgcctttcgcccgc
agcacgcagatcaccatcgccggcggcatcaccaccgaggccgacctcgccgctctcgac
gccctcggcgtcgaaggccaagtgggcatggcgctgtacacgggtcggatggacctgggc
gactcagtgggcgctctgctgaggagcgaccggcccgacggtctgttcccgacggtggtg
gccgacgagcgcggcgcggtgctgggcatggcctactccaaccgcgagaccctcaagctg
gccatcaaggagaagaagggcatctactactcccgcaagcgcggcgtctggcgcaagggc
gagaccagcggcgccatgcaacagctcctcaaggtggatgtggactgcgaccgagacacg
ctactcttcaccgtgcgccagtccggccagggcttctgtcaccgcgcctcctacaattgc
ttcggcgagggcgagcggggcctttcggggctgatgcgtactctggcctcgcgcaagcag
tcggctcccgagggctcctacaccaagcgcctcttcgacgaccccaccctcctcaaggcc
aaactgctcgaggaggctactgagctcgccgatgctgaaggcaaggagcacgtcgccaac
gaggcggccgatcttctctactttgcgctggtggcctgcaccaaggccggcgtcaccctg
tccgacgtcgagcacgtccttgaggcgcgttcgctcaaggtggcgcgccgacccggccac
gccaagcagccgttcctcaacctcgtcaacaagcagcagcaagagaccgcggccgcggcc
aaggccaagcaggtcgagagcgagaagtctgcggcgaaggaaagcgaggagaaggaggtc
gccctcaagcggctgcagatcgccgaggtgtgggacctgcgccgtgatgttgtcgacaag
aagacccgcgagatcgtcgaggagatcctgaacgatgtcagggacaagggcgaggaggcc
ctcgtccgccagtccgtcaggctcggcgacctcaagtccaaggaggagccctacctgcgc
tcgcaggaggatatgaaggccgcctatctctcgcttacgcccgaccagcagtcgctcctg
cagcgcaccgccgaccgcgtccgcgccttcgccgttgcccagaaggcctccatccagtcc
gtccaggtgcccattcccggcggtcaggccggacacacggtggcgccggtggacgtggcc
gggtgctacgcgcccggtggccgctaccccctgccctcgtcggtgctcatgaccgccatc
accgccaaggtggccggctgcaagcaagtcctcgtcgcatcgcccaacccggcacccgtc
acgctcgccgctgcctacgtggcaggcgctgattcgttgctcgctgtcggtggggcgcag
gccatcgctgccttcgcgtacggcattccaggcaagatcccctcgtgcgacgcgatcgtc
ggccctggcaacaagtttgtgacggcggccaagtcgctgatcgccggccgtgtggcgatc
gacatgctcgccggtccctccgagtgcctcgtgctggccgacggcacggcccacccggac
gtcgtggcggccgacctgctggcccaggccgagcacgacgtggcggccgtgcccatcttg
gtggcctacgacgaggagaccgtgcgccgggtcgaacaggaggtcgaggctcagctcgcc
accctgcccaccgctgccatcgcccgcgccgccttctccaacggttttgctgtgattgtc
gcgaacgaagaggaggccatcacggtgtgcgacaagctcgcgcccgagcacttggaggtc
cacaccgccaacgcggaggagctctcgcgcaagctcaaccactacggtgccctgttcgta
ggcaacaactcggccgaggtcttcggcgactacggcgccggacccaaccacaccctgccc
accagcggaactggtcgttcgttcggcgggttgtcggtcatgtccttcctccgtgtgcgc
acctggctcaacatcgacgacctcaagtcccagcccgcgcagcagctggtccaagattcg
gtcgatctggcgctgctcgagggactccacggccacgcgcgctcggcccagaagcgcctc
gtccccaaggaccaggtcaccgcggcgtcgtcgtcggcggtggtgcccatcccggccgtc
ttcggatcgccccgcgagccggtggtcatcaacttcgccctccccaagggccgcatgatg
gacaacgtcgtcaccctgctcaaggacgcgggcatttcgatcaatgtgggcggacgcaac
ctgcggcccaccatcaacctgcccggctggacggtcaagctgctcaagccccgaaacgtc
gtcgagatgatccaccacggcacccgcgacgagttgggcgcggatgacgtggttccctac
ttcgacacgggcctcgacccggtgcgcgtggtggtggcggcacccgagaagcttctggtc
gacggccagctgcccaagcgccacatgcgcctggccaccgagtacgtggccctggccgag
aagtgggtcaaggcccacggcgtcgacgccgagatttacaagaccttcggctcgaccgag
gtcttcccgcccgacgacgccgagatcatcgtcgacaacaccgcgacgggcaccaccctg
cgggccaaccagctggccatcgtcgatgagatcaccaagtcctccaccttcctctgcatc
aaccgcaccgcgctggaggacccgcgtaagcacgcggcgttggacgagttcgtgatcctc
ctgcagtcggcgctcaacgcccgcgagaaggccctgatcgagttcaatgtcgagaagtcg
tgcctggagtcggtcatcgcgggcctgccctcgatgaagcggcccaccatctcgacgctc
tacggcgacgagggcttcgccgtgcggtcggtcatccctcgcaaggcgctcgtgagcctc
gtgccctggatcaaggccaacggcgggtccgacgtcatcgtcaccgagatcaagcaggtc
atcgtctag
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