Acanthamoeba castellanii: ACA1_267180
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Entry
ACA1_267180 CDS
T02667
Name
(RefSeq) carbamoylphosphate synthase, large subunit
KO
K11540
carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:
6.3.5.5
2.1.3.2
3.5.2.3
]
Organism
acan
Acanthamoeba castellanii
Pathway
acan00220
Arginine biosynthesis
acan00240
Pyrimidine metabolism
acan00250
Alanine, aspartate and glutamate metabolism
acan01100
Metabolic pathways
acan01110
Biosynthesis of secondary metabolites
acan01240
Biosynthesis of cofactors
Module
acan_M00051
De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:
acan00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
ACA1_267180
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
ACA1_267180
00220 Arginine biosynthesis
ACA1_267180
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
acan01002
]
ACA1_267180
Enzymes [BR:
acan01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.2 aspartate carbamoyltransferase
ACA1_267180
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.2 In cyclic amides
3.5.2.3 dihydroorotase
ACA1_267180
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)
ACA1_267180
Peptidases and inhibitors [BR:
acan01002
]
Cysteine peptidases
Family C26: gamma-glutamyl hydrolase family
ACA1_267180
Metallo peptidases
Family M38: beta-aspartyl dipeptidase family
ACA1_267180
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
CPSase_L_D2
CPSase_L_D1
GATase
OTCace_N
CPSase_sm_chain
OTCace
CPSase_L_D3
ATP-grasp
Dala_Dala_lig_C
MGS
DHOase
Amidohydro_1
ATPgrasp_Ter
ATP-grasp_3
Peptidase_C26
ATP-grasp_4
ATP-grasp_5
Motif
Other DBs
NCBI-GeneID:
14920241
NCBI-ProteinID:
XP_004341545
UniProt:
L8H1T2
LinkDB
All DBs
Position
Unknown
AA seq
2265 aa
AA seq
DB search
MEKQQISGSRGATLVLSDGTRYRGVSFGAERSVGGECVFQTGMVGYVESLTDPSYRGQLL
VLSYPLIGNYGAPPEDDVDEHGLSRFMESDQVHISALIVADYSAHYSHWNAQQSLGDWLK
AHKVPAIHSIDTRALIKKIRETGSMLAKIVLDGDDEQAVELEDPNQRHLVAEVSRKQPQT
YGSGSINVVAVDCGMKNNQVRCFLKRGVKVKVVPWDWPLLEEKDAHGFFLSNGPGDPTFC
QKTIENVRALLARESAKEDPIPVFGICLGNQIMGLAAGAKTYKLKFGNRGHNQPCVDVNT
QRCHLTSQNHGFAIDSATLPEGWQELFYNANDKTNEGIQHLTRPFFSCQFHPEAKGGPWD
TEYLFDYFLAKITKQKVDLPMARASPPKNENVLKGKLHKVLILGSGGLSIGQAGEFDYSG
SQAIKALKQEHIQTILINPNIATVQTSPGLADKVYFLPVTPEFVVKLIEWERPDGILLTF
GGQTALNCGIELYKQGVFEKYNVRVMGTPLEAIIATEDREVFAQELVKINEKIAPSVAAR
SLDEALKAAEKIGYPVVVRAGFALGGLGSGFANDVDELRKLATMAFAQSEQVLVEKSLKG
WKEIEYEVVRDAYDNCVTVCNMENFDPLGIHTGESIVVAPSQTLSDQDYFMLRDVAIRVV
RHLGIVGECNIQYALNPDSEEYFIIEVNAHQPLMRPRDKLLNVNARLSRSSALASKATGY
PLAFIAAKLALGVPLPSLRNSVTKTTTACWEPSLDYVVVKMPRWDLQKFQKVDGQIGTSM
KSVGEVMAIGRTFEETIQKAIRMVNGSQWDGFQSGLAPACTDALTNPSSNRILVIAQALH
EGLSVEEIHQLTKIDRWFLHKLKSLSDFEKTLRRLDGGLTYDLLAQAKRLGFADKQIAKF
LNSTELVVRKTRKEFNIVPRIKQIDTVAAEFPAYNNYLYATYNGIEDDVETPGSAGAAAA
AAVAPAVAPTGKADEAERPIIVLGSGAYCIGSSVEFDYCAVRCAQTLKKLGKTTIMINYN
PETVSTDYDECDKLYFEELSFERVVDIYESELAAGVVVSMGGQIPNNMSMALGRQGVRIL
GTTPEMIESSENRFKFSRMLDLEGVDQPKWKDCTHLEETKRFCAEVGYPCLVRPSFVLSG
AGMTVVNTPTELETYLSLASVIDTGKEQRVVISKFIMNAKEVDLDAVAQDGEIIALAISE
HVENAGVHSGDATLILPAQDLDQVTVRKIEAAARKIAKQLQVSGPFNMQFIAKDNEIKVI
ECNLRASRSFPFVSKTLGIDFIELATKALLGLPLTPQPLPKVNHVGVKVPQFSFSRLPGA
DPVMGVEMASTGEVACFGNNKYEAYMKALLSTGFKLPKKRNIFLSLGPYKEKLEFLDSAQ
KLVNMGYNLFGTGGTADFLSEHSIPIKALSWDQEAEESNLETLSAHLSAAMIDLCIILPS
NNRNRRPASFMSKGYMARRLAINYSVPLITNIKCAKLFIECLRVVPADIPIGLVDSRASS
RTVILPGLIDVHVHVREPGASHKEDWDTCTAAALAGGITTICAMPNTNPEVIDAASMDLV
TGIAKSKARCDYGIYFGASSDNAHVGPQFANQAVALKMYLNQTFTRLRLDDMSTWMEHFT
HWPKDLPIVVHAEATTMAAALMVATLHDRALHIAHVCLKEELAVIRAAKEKGIRVTCEVC
PHHLYLDKEHACEAHHLTDGRREVRPRLATQVDVEALWANMDIIDCIATDHAPHTLAEKD
GPNPPPGFPGLETALPLMLTAVNQGRITLEDVIAKMYTNPKRIFNLPDQEDTYVVVNMDD
KWTVPKAMAHSKCGWTPFAGMELQGRVVRVVLRGKTAMLDGTVYSLPGEGRNVCAAGAAR
PRPAAVSAGLSATAAPVVSTKPAVATPSPVAQRPQIAITPPAMRRVPSAAQPALAGAAEL
QPLAQAQQQQPKALAERRNSALSQEIFTHSGALPPRFTAKHVTSVKQFTRDDLRYLFSVA
HDMRMMVKKTGSWDLLKGKVLANVFYEPSTRTSSSFHAAMLRLGGTVISVNESSSSVAKG
ESLPDTIRTLECYSDLIVLRHPQAGAAQLAASHARVPIINAGDGIGEHPTQALLDAFTIR
EELGTINGLRITMVGDLKNGRTVHSLVHLLSLYSIAQLNYVSPESLKMPSAILDELDKKG
IPQRECRSLEEALPHTDVLYVTRIQKERFASEEEYLAVKGTYVVTPEMLSHAKSNMVVMH
PLPRVDEISPEIDSDPRAAYFRQMENGMYIRMALLATILNSNFSS
NT seq
6798 nt
NT seq
+upstream
nt +downstream
nt
atggagaagcagcagatcagtggcagcaggggagcgacgctcgtgctgtcggacgggacg
cgctaccggggcgtgagcttcggcgccgagcggagcgtgggcggcgagtgcgtcttccag
acgggcatggtgggctacgtggaatcgctcacggatccatcgtaccgcggccagctgctc
gtcttgtcctacccgctcatcggcaactacggtgcccctccggaggatgatgtggacgag
catgggctgtctcgcttcatggagtcggaccaggtgcacatctctgccctcatcgtggcc
gactactccgcccactacagccactggaatgcgcagcagtcgctgggcgattggctgaag
gcgcacaaggtgccggccatccactcgattgacacccgagcgctgatcaagaagattcgt
gagacgggctccatgctggccaagatcgtgctggacggcgacgacgagcaggccgtcgaa
ctcgaggaccccaaccagaggcacctcgtcgccgaggtctcgcgcaagcagccgcagacc
tacggcagcggaagcatcaacgtggtggccgtggattgcggcatgaagaataaccaggtg
cgatgcttcctcaagcgcggcgtcaaggtcaaggtcgtgccgtgggactggcccctgctc
gaggagaaggacgcccacggcttcttcctctccaacggtcctggcgatcccaccttctgc
cagaagaccatcgagaacgtgagggcactcctggcgcgcgagtcggcgaaggaggacccc
atcccggtgtttggcatctgcctgggcaaccagatcatgggcctcgccgccggtgccaag
acctacaagctcaagttcggcaaccgtggccacaaccagccgtgcgtggacgtcaacacc
cagcggtgccacctgacctcgcagaaccacggattcgcgatcgactcggccacgctgccc
gagggctggcaggagctgttctacaacgccaacgacaagaccaacgagggcatccagcac
ctcacccggcccttcttcagctgccagttccaccccgaggccaagggtgggccgtgggac
accgagtacctgttcgactacttcctcgccaagatcaccaagcagaaggtcgacctcccc
atggcccgcgcctcgccgcccaaaaacgagaacgtgctcaagggcaagctccacaaggtc
ctcatcctcggctccggcggtctctccatcggtcaagccggtgagttcgactacagtggg
tcgcaggccatcaaggccctgaagcaggagcacattcagaccatcctcatcaaccccaac
atcgccaccgtccagactagccccggcctggccgacaaggtctatttcctgccggtgact
cccgagttcgtggtcaagctgatcgaatgggagcggcccgacggcatcctcctcaccttc
ggcggtcagactgcgctcaactgcggtatcgaactctacaagcagggcgtgtttgagaag
tacaacgtgagggtgatgggtaccccgcttgaggccatcatcgccacggaggacagggag
gtgttcgcccaggagctggtcaagatcaacgaaaagatcgcgccctccgttgccgcgcgt
tcgctcgacgaggccctgaaggccgccgaaaagatcggttaccccgtggtggtgcgggcc
ggctttgcgctcggcggcttgggctcgggcttcgcgaacgacgtcgacgaattgcggaag
ctggccacgatggccttcgcgcagtcggagcaggtcctggtcgagaagtccctcaagggc
tggaaggagatcgaatatgaggtcgtgcgggatgcgtacgacaactgcgtgacggtgtgc
aacatggagaacttcgatccgctgggtatccacacgggcgagtccattgtggttgcgccc
tcgcagaccctgtccgaccaggactacttcatgctgcgcgacgtggccatccgcgtggtg
cgccacctgggcatcgtgggcgagtgcaacatccaatacgcgctcaaccccgactcggag
gagtacttcatcatcgaggtaaacgcgcaccagcccctaatgcgtcctcgcgacaagctt
ctcaacgtgaacgcgcgtctgtcgcgcagcagtgcgttggccagcaaggccaccggctac
ccgctggccttcatcgccgccaagctggccctgggcgtgccgctgccctcgctccgcaac
tcggtcaccaagaccaccaccgcctgctgggagccctcgctcgactacgtcgtcgtcaag
atgccccgctgggaccttcagaagttccaaaaggtggacggccagattggcacatcgatg
aagtctgtgggcgaggtgatggcgatcggccgtacgttcgaggagacgatccagaaggcc
attcgcatggtcaacggctcgcagtgggacggcttccagagcggcctcgcgcccgcgtgc
accgacgccctcaccaacccctcctccaaccgcatcctcgtcatcgcacaggcgctccac
gaaggtctgagcgtggaggagattcatcagctgacgaagatcgaccgctggttcctgcac
aagctgaagagcctctccgacttcgagaagaccctccgccgactcgacggcgggctcacc
tacgacctgctcgcccaggccaagcgtctgggcttcgccgacaagcaaatcgccaagttc
ctcaactccaccgaactcgtcgtccgcaagacgcgcaaggaattcaacattgtgcccagg
atcaagcagatcgatacggtggctgccgaattcccggcctataacaactacctctacgcc
acctacaacggtatcgaggacgacgttgagacccccggcagcgccggcgcggctgcggct
gcggccgtcgccccggcggtggcccccacgggcaaggccgacgaggccgagcggcccatc
attgtgctcggcagcggtgcctactgcatcggcagttcggtcgagttcgactactgcgct
gtgcggtgcgcgcagacgctcaagaagctgggtaaaacgacgatcatgatcaactacaac
ccggagacggtgtcgaccgactacgacgagtgtgacaagctctacttcgaggagctctcg
ttcgagcgcgttgtcgacatctatgagagcgagctggccgccggcgtcgtcgtctccatg
ggcggacaaattccgaacaacatgtcgatggcccttgggcgccagggcgtgcgcattctg
ggcacgaccccggaaatgatcgagagctcggagaaccggttcaagttctcgcgcatgctc
gacctcgagggcgtcgaccagcccaagtggaaggactgcacccacctcgaggagaccaag
cgcttctgcgccgaggtgggctacccgtgcctggtccggccgtcgttcgtgctcagcggc
gccggcatgaccgtcgtcaacacgcccaccgagctcgagacctatctgagcctcgccagc
gtcatcgacactggcaaggagcagcgcgtcgtcatctcaaagttcatcatgaacgcgaag
gaggtggacctggacgcggtggcgcaggacggcgagatcatcgcgctcgccatctcggag
cacgtcgagaacgccggcgtgcactcgggcgacgcgacgctcatccttcccgcgcaggac
ctcgaccaggtgaccgttcgcaagatcgaggccgccgcgcgcaagatcgccaagcagctg
caggtgtcgggtcccttcaacatgcagttcatcgccaaggacaacgagatcaaggtcatc
gagtgcaacctgcgcgcgtccaggtcgttcccgttcgtgtccaagacgctgggcatcgac
ttcatcgagctcgcgacgaaggccctgctcggcctcccgctcaccccgcagcccctgccc
aaggtcaaccacgtgggcgtcaaggtccctcagttctcgttctcgcggttgccgggcgcc
gatcccgtgatgggcgtcgagatggcctccaccggtgaggtcgcctgcttcggcaacaac
aaatacgaggcctacatgaaggcgctgctgtcgacgggcttcaagctgcccaagaagagg
aacatcttcctctcgctgggtccctacaaggagaagctcgagttcctcgacagcgcccag
aagctcgtcaacatgggctacaacctgttcggcaccgggggtacggccgatttcctgagc
gagcacagcatcccgatcaaggcgctgagctgggaccaggaggccgaggagagcaacctc
gagacgctctcggcgcacctgtcggcggcgatgatcgacctgtgcatcatcctgccctcc
aacaaccgcaaccgccgcccggcctcgttcatgagcaagggctacatggcccgccgactc
gccatcaactactccgtcccattgatcaccaacatcaagtgcgcgaagctcttcatcgag
tgcctgcgtgtggtgccggccgatatccctatcgggctcgtggacagccgcgcctcgagc
cgtacggtgatcctgccgggcctgatcgatgtccacgtgcacgtgcgcgagcctggcgcg
tcgcacaaggaggactgggacacctgcaccgccgccgcactcgccggtggtatcaccacg
atctgcgcgatgcccaacacgaacccggaggtgatcgacgcagcctcgatggatctggtg
acgggcatcgccaagagcaaggcccgctgtgactacggaatctactttggcgcctcgtcc
gacaacgcccacgtcggaccgcagttcgccaaccaagccgtcgcgctcaagatgtacctc
aaccagaccttcacccgtctgcgcttggacgacatgagcacgtggatggagcacttcacc
cattggcccaaggacctgcccatcgtcgtccacgctgaagcgacgaccatggcggcggcc
ttgatggtggcgacgctgcacgaccgcgcgctgcacatcgcccacgtgtgcctgaaggag
gagctggcggtcatccgcgcggccaaggagaagggcatccgcgtgacgtgcgaggtgtgc
ccgcaccacctctacctcgacaaggagcacgcctgcgaggcccaccacctcaccgacggc
cgccgcgaggtgcgcccgcgcctggcgacccaggtcgacgtcgaggccctgtgggccaac
atggacatcatcgactgcatcgccaccgaccacgccccgcacaccctggccgagaaggac
ggacccaacccgccgcccggcttccccggccttgagaccgccctgcccctcatgctcacc
gccgtcaaccagggacgtatcacgttggaagatgtgatcgccaagatgtacaccaacccc
aagcgcatcttcaacctgcccgatcaggaggacacgtacgtggtggtgaacatggacgac
aagtggaccgtgcccaaggccatggcccactctaagtgcggctggaccccgttcgccggc
atggagctgcagggccgcgtcgtgcgcgtcgtgctgcgcggcaagaccgccatgctcgac
ggcaccgtctactcgctccccggcgagggacgcaacgtatgcgccgcgggcgccgcccgg
cctcgcccggccgccgtctctgctgggctctcggctaccgccgctcccgtcgtctcgacc
aagcccgccgtcgccacgccgtcgcccgtcgcccagcggccccagatcgcgatcacgccg
ccggccatgcgacgcgtgccgtcggctgcccaaccggccctggccggcgccgccgagctg
cagccgctggcgcaggcccagcagcagcaaccgaaggcgcttgccgagaggcgcaactcg
gcgctgtcgcaggagatcttcacccacagcggcgccctgcctccgcgcttcaccgccaag
cacgtgacgtcggtcaagcagttcactcgcgacgacctccgttacctcttctccgtcgcc
cacgacatgcggatgatggtgaagaagacaggatcgtgggacctgctcaagggcaaggtg
ctggccaacgtgttctacgagccgtcgacccgcacctcgtcgtcgttccatgcggccatg
ctgcgtctgggcggcacggtgatctcggtcaacgagagctcgtcgtcggtggccaagggc
gagtccctgcccgacactatccgcaccctcgagtgctactcggacctcatcgtgctccgc
cacccgcaggccggcgccgcccaactcgccgcctcccacgcgcgcgtgcccatcatcaac
gccggcgatggcatcggcgaacaccccacccaggctctgctcgatgcgttcacgattcgt
gaggagctgggcacgatcaacgggctgcgcatcacgatggtgggcgacctcaagaacggc
cgcaccgtgcactcgctcgtgcacctcctctcgctctacagcatcgcccagctcaactac
gtctcgcccgagtccctcaagatgccctccgccatcctcgacgagctcgacaagaagggc
attccgcagagggagtgcaggtcgctggaggaggcgctgccccacaccgacgtgctctac
gtgacgcgcatccaaaaggagcgattcgccagcgaggaggagtacctcgccgtcaagggc
acgtacgtggtcacacccgagatgctgtcgcacgccaagagcaacatggtcgtcatgcac
cccctcccgcgcgtcgacgaaatcagccccgagatcgacagcgatccccgcgcggcgtac
ttccgacagatggagaacgggatgtacattcgcatggccctccttgccaccatcctcaac
tccaacttctcttcctaa
DBGET
integrated database retrieval system
