KEGG   Aquarana catesbeiana (American bullfrog): 141138997
Entry
141138997         CDS       T11018                                 
Symbol
CAD
Name
(RefSeq) multifunctional protein CAD isoform X1
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
acat  Aquarana catesbeiana (American bullfrog)
Pathway
acat00220  Arginine biosynthesis
acat00240  Pyrimidine metabolism
acat00250  Alanine, aspartate and glutamate metabolism
acat01100  Metabolic pathways
acat01240  Biosynthesis of cofactors
Module
acat_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:acat00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    141138997 (CAD)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    141138997 (CAD)
   00220 Arginine biosynthesis
    141138997 (CAD)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:acat01002]
    141138997 (CAD)
Enzymes [BR:acat01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     141138997 (CAD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     141138997 (CAD)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     141138997 (CAD)
Peptidases and inhibitors [BR:acat01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   141138997 (CAD)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   141138997 (CAD)
SSDB
Motif
Pfam: CPSase_L_D2 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 ATP-grasp MGS Dala_Dala_lig_C ATPgrasp_Ter RimK Amidohydro_1 ATP-grasp_3 GARS_A DJ-1_PfpI Peptidase_C26 GSH-S_ATP
Other DBs
NCBI-GeneID: 141138997
NCBI-ProteinID: XP_073480858
LinkDB
Position
LG04:2254984..2328061
AA seq 2264 aa
MAAEMAELILEDGSRFTGTFIGQSRPVSGEVVFQTGMVGYPEALTDPSYKSQILILTYPL
VGNYGIPADQLDEFGLSKWFESARIHVSALIVGECSDKPSHWSCSLSLDQWLKEQGIPGL
QGVDTRALTKKIREKGTMLGKLIPQGSSEDHIPYDDPGKRNLVQEVSVKEPRVFNRGGDV
KIAALDCGLKYNQIRCLCQRGAEVTVLPWDSPINRADFDGLFLSNGPGDPLFCQESVQNI
RNFMNEDQPKPVFGICLGHQILSLVIGAKTYKMKYGNRGHNQPCIHEGSRRCFITSQNHG
YAVDPKTLPEGWSPLFTNANDKSNEGIVHDSKPFFSVQFHPEHRAGPMDLVCLFDVFLDT
VRDIKAGRVGGVTVKQRLDDILTYKDSPNVSELIACRPRKVLILGSGGLSIGQAGEFDYS
GSQAIKALKEENIQTVLINPNIATVQTSKGLADKVYFLPITAEYVTQVIKSERPDGVLLT
FGGQTALNCGVELTKRGVLEMYNVRVLGTPVKSIEMTEDRKIFVEKMEEIGEHVAPSEAA
SSLEQAQAAADRLGYPVLVRSAYALGGLGSGFANSKEELTSLVCQAFAHTTQVLVDKSLK
GWKEIEYEVVRDAYNNCITVCNMENVDPLGIHTGESIVVAPSQTLNDHEYNMLRNTAIKV
IQHLGIVGECNIQYALNPHSEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPL
PVLRNSVTNSTTANFEPSLDYCVVKVPRWDLSKFLRVSTKIGSSMKSVGEVMSVGRNFEE
AFQKALRMVDENCVGFDHTLKAESDEELETPTDKRIFVLAAALRAGYTIERLYELTKIDR
WFLHKMKNITDHLSTLESYQGDTAMTRDVLLRAKQLGFSDKQVAIAVQSTELAVRKLRQE
WQILPVVKQIDTVAAEWPAQTNYLYLTYNGIEHDLSFEEPHVMVIGSGVYRIGSSVEFDW
CAVGCIQELRKMGFKTIMVNYNPETVSTDYDMCNRLYFDEISFEVVMDIYELENPEGIIL
SMGGQLPNNIAMSLHRQQCRVLGTSPDSIDSAENRFKFSRLLDTIGISQPQWKELSDMKS
ALQFCNSVGFPCVVRPSYVLSGAAMNVAHCDEDLEKVLSNAVAVSKEHPVVISKYIQEAK
EIDVDAVACDGVVVAIAICEHVENAGVHSGDATLVTPPQDITPKTLERIKAIVHAVGLEL
QVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDMVALATQVIMGEEVEPVGLM
TGMGIVGVKVPQFSFSRLAGADVVLGVEMTSTGEVACFGENRYEAYLKAMLSTGFKIPQK
NILLTIGSYKNKSELLPTVRALETLGYSLYASLGTADFYTEHGIKIKAMDWVFEDPDCDG
PMKEKQGSIMDHLSENHFDLVINLSMRNSGGRRLSSFVTRGYRTRRLAVDYSVPLIIDIK
CTKLFVEALRQIGTNPPVKTHVDCMTSQKFIRLPGLIDVHVHLREPGATHKEDFSSGTAA
ALAGGVTMVCAMPNTKPAITDANTFSLAHKLAEAGARCDFALFLGACSENAGSLSSIASS
AAGLKMYLNDTYSQLKMDNVSLWMEHFEKWPSHLPIVAHAENQTVAAILMVAQLYKRSVH
ICHVAKKEEILIIKAAKQKGIKVTCEVAPHHLFLCLDDLDRLGDKKGQVRPMLGTREDMQ
ALWDNLDIIDCFATDHAPHTVEEKEGPNPPPGFPGLETMLPLLLTAVSDGRLMMDDIIKR
LYDNPRKIFSLPVQENTYVEVDLEHEWVVPQCMQFTKSKWTPFEGMNLKGAVRRVVLRGE
VAYIDGQVLVPAGYGQDVRKWTPPLAPQTVPTQNKEVNKTPERHRHVTMQSEIIRSRAPS
PRRAGPPAEARFHLPPRIHRASDPGLPVSRRMSVTQLRGTAWKIAEEPLKDRAKKSSDTD
LSSIQDGYSYPPPIPRLVSPQNVAMQSVPHVQTSPLLHPLIGQHILSVRQFTKDQMSHLF
NVAHTLRMLVQKERSVDILKGKVMASMFFEASTRTSSSFAAAMQRLGGSVLTFSETTSSS
QKGESLTDSVQTMSCYSDVLVVRHPEPGAVELAAKHCRKPVINAGDGVGEHPTQALLDIF
TIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRINLRYVTPRSLRMPPKIIHFVAS
KGIKQEEFDSIEEALLDTDVLYMTRIQKERFDSKEEYDRCFGQFILTPHIMTRAKKKMVV
MHPMPRVNEISFEVDSDPRAAYFRQAENGMFVRMALLATVLGKY
NT seq 6795 nt   +upstreamnt  +downstreamnt
atggcggcggagatggcggaactgatcctggaggacgggagccgcttcaccggcaccttc
atagggcagagccggcccgtgtccggggaagtggtcttccagacgggcatggtgggctac
cccgaggctctgacggacccttcatacaagtctcagatcctgatcctcacatacccgctg
gttgggaactacgggattcccgcggatcaacttgatgagtttggtcttagcaagtggttt
gaatccgctcggatccacgtctcggcgctcatcgtgggagagtgctcggacaagcccagc
cactggagctgcagcctgtcgctggaccaatggctgaaagagcaggggatcccaggcctg
caaggtgtggacacccgagccctcaccaaaaagatccgggagaagggaaccatgctgggc
aagcttatcccacaaggctcgagcgaggaccacatcccctacgatgatcctggaaaaagg
aacctggtgcaggaggtgtccgtgaaggaaccgcgtgttttcaaccgtggaggcgatgtg
aagattgcggccctggactgcggtctgaaatacaaccagatccgctgcttgtgccagaga
ggggcggaggtgaccgtactgccctgggactctcccatcaaccgtgcagactttgacggg
ctgtttctcagtaatggtcctggagatccgctcttctgccaggagtctgtccagaacatc
cgaaacttcatgaatgaagaccaaccaaagccggtgtttggaatctgcctggggcaccag
atcctgtccctggtcatcggggccaagacctacaagatgaagtatgggaaccgtggccat
aaccagccgtgtatccacgagggctcccgaagatgcttcatcacctctcagaatcatggc
tacgccgtcgaccccaaaaccttaccagaaggctggtcaccgctctttaccaacgccaat
gataagtccaatgagggcatcgttcacgactccaaaccgttcttcagtgtgcagttccac
cccgagcaccgtgctggccccatggacttggtgtgtctgtttgacgtcttcttggacacc
gtgcgggatatcaaggctgggagagtgggaggagtcacagtgaagcagcggctggacgat
atcctcacatacaaagactctcccaacgtgtcggagttgattgcctgcagacctcgtaaa
gtgctgatcctgggctctggggggctctctatcggccaggccggggagtttgactactcg
ggatcccaggccattaaagctctgaaagaggaaaacatccagacggtgctgattaacccc
aacattgccacggtgcagacctccaaggggcttgcggacaaggtgtactttctgccaatc
acagcagaatatgtaacacaggtgataaagagcgagaggccggatggcgttctcctgacc
tttggtggtcagacggctctgaactgcggggtggagctgacgaaacgcggggtgctggag
atgtacaatgtgcgtgtcctgggcaccccggtgaagtccattgagatgacggaagaccgg
aagatctttgtggagaagatggaggagatcggggaacatgtggcaccaagtgaggccgcc
tcctcgctggagcaggctcaggctgccgctgaccgtctggggtacccggtcttggtacgt
tcggcctacgcacttggtgggctgggctctggcttcgccaactcgaaagaggagctaacg
tccctggtgtgccaggcattcgcccacaccacgcaggtcctggtggacaaatcactgaag
gggtggaaggagatcgagtatgaggtggtgagagatgcctacaacaactgcataactgtg
tgtaacatggagaatgtggaccctctaggtatccacactggggagtccatagtggtggcg
cccagccagacactgaatgaccatgagtacaacatgctacgcaacactgctatcaaggtg
atccagcacctgggcattgtgggagagtgcaacatccagtatgccctgaacccgcactct
gaacagtattacatcattgaggtgaacgcgcggctctcacgcagctcggccctggcaagc
aaggccaccggataccccctggcatatgtggcagccaaactggcattagggatccctctt
ccggttctcagaaactctgtcaccaactccaccacagccaactttgagcccagcttggat
tactgcgtggtgaaggtcccccgctgggatcttagtaaattcctacgagtcagcaccaag
attggcagctcaatgaagagcgtgggggaagtcatgtcggtgggacggaatttcgaggaa
gctttccagaaggcgctgcgcatggtggatgagaactgcgtggggttcgaccacacgttg
aaagcggagtccgatgaggagctggagacccccacggacaagcgaatatttgtgctggca
gcagctctgcgggccggctacaccatcgagcgcctgtacgaactgacgaagatcgaccgc
tggttcctccacaagatgaagaacatcaccgaccacctatccacactggagtcctaccag
ggcgacaccgccatgacccgggatgtcctgctccgtgccaaacagctgggcttctccgac
aagcaggtggcaatagctgtgcagagcacggagctcgccgtccggaagttgcggcaggaa
tggcagatccttccggtagtgaagcagattgacacggtggccgctgagtggccggcacag
accaattacctgtacctgacctacaacggcatagagcacgacctgtcatttgaggagcca
cacgtcatggtgatcggctccggcgtctaccgcatcggcagcagcgtggagttcgactgg
tgtgcagtgggctgtatacaggaactgcgcaagatgggcttcaagacgattatggtgaat
tataacccggagacggtcagcactgactacgacatgtgcaacaggctctactttgacgag
atctccttcgaggtggtgatggacatctatgagctggagaacccagaggggatcatcttg
tccatgggaggccagctaccaaacaacatagccatgtccctgcaccgacagcagtgccgc
gtcctgggcacctcgcctgactccattgactcagccgaaaatcgcttcaagttttcccgc
ctgctggacaccattgggatcagccaaccacagtggaaggagctgtctgatatgaagtct
gctctgcagttctgtaactctgtggggttcccctgcgtggtgcgcccgtcctacgttctt
agcggggctgccatgaacgtcgcgcattgtgacgaagatctggagaaagttctcagcaac
gctgtggccgtgtccaaagaacatcctgtggtgatctccaaatacatccaggaagccaag
gaaatagacgtggatgctgtggcctgtgatggggtggtggtggcaattgccatctgtgag
catgtagagaatgccggagtccactctggagatgccacactggtcacccctcctcaggac
atcacccccaaaaccctggagcggatcaaagccattgtccatgcggtggggttggagctc
caggtgaccggacccttcaacctgcagctcattgccaaggacgatcagctgaaagtgatc
gagtgcaacgtccgagtctctcgctccttccccttcgtctccaagactttaggggtggac
atggtggctctggccacacaggtgatcatgggagaggaggtggagccggttggactgatg
acggggatgggaattgtgggtgtgaaggtgcctcagttctccttctctcgtctggccgga
gcagatgtggtcctcggggtggagatgaccagcacgggggaggtggcctgctttggagag
aaccgctacgaagcctatttgaaggcaatgctgagtactggctttaagattccacagaag
aacattctgctgaccatcggaagctacaagaataagagcgagctcctgcccaccgtgcgg
gccctggagaccctcgggtacagcctgtacgccagtcttggcacagccgacttctatact
gaacacggaatcaagattaaggcgatggattgggtctttgaagatccggactgcgatggg
cccatgaaggagaagcaggggagcatcatggaccatctgtccgagaaccattttgatctg
gtcatcaacctctccatgagaaattctggcggtcgcaggctttcctccttcgtcacccgc
gggtaccgtactcgccgcttggcggtggattactccgttccgctgatcatcgacatcaag
tgcaccaaactgtttgtggaggctctgcgtcagattggaaccaaccctcccgtgaagacc
cacgtggactgtatgacctcccagaagtttatccgtcttccaggtctgatagacgtacac
gtccatctacgagaacctggcgccactcataaggaagacttctcctctggcactgcggcg
gctctggcgggaggtgtcactatggtgtgtgccatgcccaacaccaagccggccatcacc
gatgccaacaccttctccctggcgcacaagctagcagaggctggtgcccgatgtgacttt
gccctgttcctgggcgcctgttcagagaatgctgggtccctctcctccatcgccagctca
gcggcaggactgaagatgtatctgaacgacacgtactctcagctcaagatggacaatgtc
tctttgtggatggagcactttgagaagtggccgtctcatttgccgattgtggctcacgca
gagaaccagacagttgcagcaattctgatggtggctcagctatataagcgttcggtgcac
atctgccatgtggctaagaaggaagagatcctgatcattaaggctgccaagcagaaaggc
atcaaagttacctgtgaggtggcgccccatcacttgttcctctgcctggacgaccttgac
cgactgggggacaagaaagggcaagtgcgtcccatgctggggacccgagaggacatgcag
gccttgtgggacaacctggacattatagactgtttcgccaccgatcacgccccccacact
gtggaggagaaggaagggccaaaccctccccctgggtttcccggcctggaaactatgctt
cccctactgctcactgccgttagcgacggacgactgatgatggatgacatcatcaagcgc
ctgtatgacaacccccgcaaaatattctcactgccagtacaagaaaatacatatgttgag
gtggatttggaacatgagtgggttgtccctcagtgtatgcagttcaccaaatccaagtgg
actccatttgagggaatgaatttgaagggagctgtgcgtagggtcgtcctgcggggtgaa
gtggcgtacattgatggacaggtccttgtgccggctggttacggtcaggatgtcaggaag
tggactcctccactggctcctcagactgttcccacccagaataaagaagtcaataagact
ccggaacgccatcgtcatgtgaccatgcagagtgaaatcattcggagccgggcccccagc
cctcggagagccggccctcctgctgaagcccgcttccatctgccacccagaatccaccgc
gcatctgaccccggcctgccagtgtccaggaggatgtctgtcactcagctcagagggact
gcttggaagatcgccgaggagccgctaaaggacagagccaagaagtcttctgacacagat
ctatcatctattcaggatggttattcctacccgccccccatcccccgtctcgtgtccccc
cagaacgtggcgatgcagagtgtccctcacgtacagacctcgcccctccttcatccgctc
attggacaacacatcctgtccgtcagacagttcaccaaggaccagatgtcccacctgttc
aacgtggcacacacactgcgaatgttggtacagaaagagcgtagtgtcgatatattgaag
ggtaaggtcatggcatccatgttcttcgaggccagtacacggaccagcagttcctttgca
gcagccatgcagcgtctgggagggtcagtgctcactttctcagagacaacatcatcctcc
cagaagggtgaatctttgacggattctgtgcagacgatgagctgttactccgacgtgctg
gtggtgagacatccggagcccggagcggtggagctggctgccaaacactgccgcaagccg
gtcatcaatgccggagatggggtaggggagcacccaacacaggctctgctggatatattc
accatacgggaggagctggggactgtcaacgggatgactatcaccatggtgggggatttg
aagcacggccgtacggttcactctctggcgtgcctcctcacccaataccgtatcaacctg
aggtatgtcacgccacgcagcttgaggatgccccctaagatcattcactttgtggcttcc
aaaggaatcaaacaggaagagtttgacagcattgaagaggctttgctggacacggacgtc
ctctacatgacccgcatacagaaggaacggtttgacagcaaggaggagtatgaccggtgc
tttggccagtttatcctcaccccgcacatcatgacccgggccaagaagaaaatggtggtc
atgcacccaatgccgcgagttaatgagatcagctttgaagttgactcggacccccgcgct
gcctacttccgccaggctgagaacggtatgtttgtacgcatggcactgctggccacagtc
ctggggaagtactga

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