Actinomyces sp. HMT 175: JJJ14_09210
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Entry
JJJ14_09210 CDS
T10480
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
achn Actinomyces sp. HMT 175
Pathway
achn00020
Citrate cycle (TCA cycle)
achn00630
Glyoxylate and dicarboxylate metabolism
achn00785
Lipoic acid metabolism
achn01100
Metabolic pathways
achn01110
Biosynthesis of secondary metabolites
achn01120
Microbial metabolism in diverse environments
achn01200
Carbon metabolism
achn01210
2-Oxocarboxylic acid metabolism
Module
achn_M00009
Citrate cycle (TCA cycle, Krebs cycle)
achn_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
achn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
JJJ14_09210
00630 Glyoxylate and dicarboxylate metabolism
JJJ14_09210
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
JJJ14_09210
Enzymes [BR:
achn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
JJJ14_09210
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
JJJ14_09210
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
JJJ14_09210
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
JJJ14_09210
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QQQ58688
LinkDB
All DBs
Position
2185625..2189452
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AA seq
1275 aa
AA seq
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MPTQDQISPGFGANEWMVEEMRAAWSADPSSVSPQWRELFETDPGAGLHQPGPASSNGSA
SSAAGGPRRATITPQAASSLRRSSAVQDVTRSDLPPAPPSDTAPPTSPYAQRQAAHPAHD
QDGDAYEDRTTRLKGAAARTAKNMDDSLSMPTATSARAVPAKVLIENRSVINTHLARTRG
GKVSFTHLIGWAVVESLTEMPSMNVSYGVDEAGKPVLHEPAHVAFGLAIDVPGSDGQRRL
LVPSIKQADLMDLSQFVEAYEALVAKARENKLDLDDFRGTTVTLTNPGMIGTLHSVPRLM
PGQGLIVGVGAMDYPAAFAGASPDTLARQAIGKVVTLTSTYDHRVIQGAASGEFLRLVER
KLLGLDGFWNRAFESLRIPLEPVKWVRDTTYDPELETGKPARVAELIHAYRQRGHLAADN
DPLTYRLRRHPDLDITSYGLSLWDLDRSFPTRGLGGRDRATLREILRMLRDAYCRTVGVE
YMHIQDPAQRAWWQERLERDWEDIADEERRRILTKLEQAEAFETFLQTKYVGQKRFSLEG
GESLIVALDRLLDAAAHDGLDEVVIGMAHRGRLNVLTNIAGKSYGQVFDEFEGNGVIEGA
GTGDVKYHLGTVGVFSGTDGVSTRVSLAANPSHLETVDGVVEGIVRAKQDRIGLGEKGYT
VMPVLVHGDAAFAGQGVVYETLNMSQLPAYRTGGTVHIVVNNQIGFTTGSASARSTIYAT
DLAKGLQVPIFHVNADDPETVARTARHAYEYRRTFHKDVIIDLICYRRRGHNEGDDPSMT
QPLMYRLIDSLDSTRGVYTAALVGRGDITPQEAQEIAKSYQDELERVFTEARIQVTGGTG
SDGAGDAADTSTQDLSDPTKVGVPLSSLEIPYSQRAGTGMMLGWTSAVPRDVVERIGDAQ
VAWPESFTVHPKLQAMLSKRREATREGGIDWGLGELIALGSLLMEGVPIRLAGEDARRAT
FAQRHAVLHDHTSGQEWTPLSFLTPDQAPLEIYDSLLSEYAALAFEYGYSVERPEGLTMW
EAQFGDFANGAQSVIDEYVTSAAQKWGQRSGLVMLLPHGQEGQGPDHSSARIERYLQMCA
QDNMLVAQPSTPASYFHLLREHTYTRPRRPLIVFTPKQLLRLKAACSPVEAFTSGTFQPV
IGETDDAVLASAQKQGVDRVLLCSGRVYYDLLAHRTKTGDTRTAIVRLEQLYPLESSAIA
EALAPFSGAELVWVQDEPANQGMWPYLALNLPTELTGGVLPTLVSRPEAAAPAVGTAGLH
RAQQEEILRQAFARR
NT seq
3828 nt
NT seq
+upstream
nt +downstream
nt
gtgcccacgcaggaccagatcagcccaggcttcggtgccaacgagtggatggtggaggag
atgcgggccgcctggtcggcggatccctcctccgtgagtcctcagtggcgcgagctcttc
gagaccgatccgggtgccggcctgcaccaaccgggccctgcctcctccaacggctcggcg
tcgtcggccgccggtgggccgcgccgggccaccatcacgccccaggccgcctcctccctg
cgccgctcctccgccgtccaggacgtcacgcgctccgacctgccgccggccccgccgtcg
gacaccgcacccccgacctccccctacgcccagcgccaggccgcccaccccgctcacgac
caggacggtgacgcctacgaggaccgcactaccaggctcaagggtgcggcggcccgcacc
gccaagaacatggacgattccctgtccatgccgacggccacctccgcccgggccgtaccc
gccaaggtcctcattgagaaccgctccgtcatcaacacccacctggcccgcacccgcggc
ggcaaggtctccttcacccacctcatcggctgggcggtggtcgagtccctgaccgagatg
ccctcgatgaacgtctcctacggggtcgatgaggcaggcaagccggtcctgcacgagccc
gcccacgtggccttcggcctggccatcgacgtgcccggctccgacgggcagcgtcgcctg
ctggtgccctccatcaagcaggccgacctcatggacctgtcccagttcgtggaggcctac
gaggccctcgtggccaaggctcgcgagaacaagctggaccttgacgacttccggggtacc
accgtgaccctgaccaaccccggcatgatcggcaccctgcactcggtgccgcgcctcatg
cccggccaggggctcatcgtgggggtcggcgccatggactacccggccgccttcgccggt
gccagccccgacaccctggcccgccaggccatcggcaaggtcgtcaccctgacctccacc
tacgaccaccgcgtcatccagggcgccgcctccggcgagttcctgcgcctggtggagcgc
aagctcctgggactggacggcttctggaaccgggctttcgagtccctgcgcatccccctc
gagccggtcaagtgggtgcgtgacaccacctacgaccccgagctggagaccggcaagccg
gcgcgcgtggccgagctcatccacgcctaccgccagcgcggccacctggcggccgacaac
gacccgctcacctaccgcctgcgccgtcaccccgacctggacatcacctcctacgggctg
agcctgtgggacctggaccgctccttccccacccggggcctgggcgggcgcgaccgggcc
accctgcgcgagatcctcaggatgctgcgcgacgcctactgccgcaccgtgggcgtggag
tacatgcacatccaggacccggcccagcgcgcctggtggcaggagcgcctcgagcgcgac
tgggaggacatcgccgacgaggagcgccgtcggatcctcaccaagctggagcaggccgag
gccttcgagaccttcctgcagaccaagtacgtgggccagaagcgcttcagcctcgagggc
ggggagtccctcatcgtggccctggaccgcctgctcgacgccgccgcccacgacggcctc
gacgaggtcgtcatcggcatggcccaccgcggccgcctcaacgtgctcaccaacatcgcc
ggcaagtcctacggccaggtcttcgacgagttcgagggcaacggcgtcatcgagggcgcc
ggcaccggcgacgtcaagtaccacctgggcaccgtgggcgtcttctccgggaccgacggc
gtctccacccgcgtctccctggccgccaacccctcccacctggagacggtcgacggcgtc
gtcgagggcatcgtgcgcgccaagcaggaccgcatcggcctgggcgagaagggctacacg
gtcatgccggtcctcgtccacggtgacgccgccttcgccggccagggcgtggtctacgag
accctcaacatgagccagctgcccgcctaccgcaccggcggcaccgtccacatcgtcgtc
aacaaccagatcggattcaccaccggctcggcttcggcccgctccaccatctacgccacc
gacctggccaagggcctgcaggtgccgatcttccacgtcaacgccgacgaccccgagacg
gtggcccgcaccgcccgccacgcctacgagtaccgacgtaccttccacaaggacgtcatc
atcgacctcatctgctaccggcggcgcggccacaacgagggcgacgacccctcgatgacc
cagccgctcatgtaccggctcatcgactcgctggactccacgcgcggcgtctacaccgcc
gccctcgtggggcgcggcgacatcaccccgcaggaggcccaggagatcgccaagagctac
caggacgagctggagcgggtcttcaccgaggcccgcatccaggtcaccgggggcacgggc
tccgacggcgccggagacgcggccgacacctccacacaggacctgtcggaccccacgaag
gtgggcgtgcccctgtcctccctggagatcccctactcccagcgggcgggcaccggcatg
atgctcggctggacctcggccgtgccgcgcgacgtcgtcgagcgcatcggcgacgcccag
gtcgcctggcccgagtccttcaccgtccaccccaagctccaggccatgctctccaagcgc
cgcgaggccacgcgcgagggcggcatcgactgggggctcggggagctcatcgccctgggg
agcctgctcatggagggcgtgccgatccgactggccggcgaggacgcccgccgcgccacc
ttcgcccagcgccacgccgtcctgcacgaccacacctccgggcaggagtggacgcccctg
agcttcctgaccccggaccaggcacccctggagatctacgactccctgctcagcgagtac
gccgccctggccttcgagtacggctactccgtggagcgccccgagggactgaccatgtgg
gaggcccagttcggcgacttcgccaacggcgcccagtccgtcatcgacgagtacgtcacc
tccgccgcccagaagtgggggcagcgctccggcctggtcatgctgctcccccacggccag
gaggggcagggacccgaccactcctcggcccgcatcgagcgctacctgcagatgtgcgcc
caggacaacatgctggtggcccagccctccacgcccgccagctacttccacctgctgcgc
gagcacacctacacccgcccgcgccgcccgctcatcgtcttcacccccaagcagctgctg
cgtctgaaggccgcctgctccccggtggaggccttcacctccggcaccttccagccggtc
atcggggagaccgacgacgccgtcctggcctcggcgcagaaacagggcgtggaccgggtg
ctgctgtgctcgggtcgcgtctactacgacctgctggcccaccggaccaagaccggggac
acgagaacggccatcgtccgcctcgagcagctctacccgctggagagctcggccatcgcc
gaggcactggcccccttcagcggggccgagctcgtgtgggtccaggacgagcccgccaac
cagggcatgtggccctacctggcgctcaacctgccgacggagctgaccggtggcgtcctg
ccgacgctggtctcccggcccgaggccgccgccccagcggtgggcaccgccggtctccac
cgcgcccagcaggaggagatcctccgccaggccttcgcccgccgctga
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