Actinomadura citrea: OG979_08115
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Entry
OG979_08115 CDS
T09741
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
acir
Actinomadura citrea
Pathway
acir00020
Citrate cycle (TCA cycle)
acir00630
Glyoxylate and dicarboxylate metabolism
acir00785
Lipoic acid metabolism
acir01100
Metabolic pathways
acir01110
Biosynthesis of secondary metabolites
acir01120
Microbial metabolism in diverse environments
acir01200
Carbon metabolism
acir01210
2-Oxocarboxylic acid metabolism
Module
acir_M00009
Citrate cycle (TCA cycle, Krebs cycle)
acir_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
acir00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
OG979_08115
00630 Glyoxylate and dicarboxylate metabolism
OG979_08115
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
OG979_08115
Enzymes [BR:
acir01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
OG979_08115
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
OG979_08115
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
OG979_08115
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
OG979_08115
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
WUR53902
LinkDB
All DBs
Position
1725983..1729675
Genome browser
AA seq
1230 aa
AA seq
DB search
MSTESSHTSADPMLTDFGANEWLVDELYQKYLDDPNSVDEAWWNFFADYQPDSRPASATP
QADGAAPTAANGSAAAPPTPRPPSAPPKAPAKAPAPKGDRPAPPPVPAGAEEVRLRGVAA
RTASNMEASLAVPTATSVRAVPAKLLIDNRIVINNHLKRGRGGKVSFTHLIGYAIVRALA
SMPEMNAAFTEVDGKPVLIRPEHVNFGLAIDLQKGDGSRQLVVPSIKAAETLDFRQFWAS
YEEIVRKARGGKLTLEDFQGTTISLTNPGTIGTVHSVPRLMPGQGTIIGVGAMEYPAEFA
GASSDTLARMGISKVMTLTSTYDHRIIQGAQSGDFLRRINQLLLGEDGFYDEIFEALRIP
YEPVRWVKDISATHEDDVAKVARVHELIHAYRVRGHLMADTDPLEYKQRRHPDLDILKHG
LTLWDLEREFATGGFGGKPTMKLRDILGVLRMAYCRTVGIEYMHIQDPEERAWIQERVEV
PHEKPSREEQLHVLRRLNSAEAFETFLQTKFVGQKRFSLEGGESVIPLLDSVISAAAGAS
LDEVVIGMAHRGRLNVLANIVGKSYGQIFGEFEGNLDPRSAQGSGDVKYHLGASGDFVGS
DGSKIHTELVANPSHLETVDPVLEGVVRAKQDLLDVGEAGFTVLPILIHGDAAFAGQGVV
AETLNLSQLRGYRTGGSVHVIINNQVGFTTAPEYSRSSVYATDVARMIQAPIFHVNGDDP
EMCARVARLAFEYRQTFKKDVVIDMVCYRRRGHNEGENPSFTQPLMYDLIDAKRSVRKLY
TEALIGRGDITVEEAEQALRDYQEQLERAFTETREAVKKPLEPGSVVKPDVEERIPIDHG
KAGSAIPQETVKRIIESQVSLPEGFTPHPRLQPILQRRAQMIEDDAIDWATGELLAMGSL
LIDGHPVRLVGQDTRRGTFGQRHAVLVDRRTGEEYTPLKQFGQGVSKFYAHDSLLSEYAA
MGFEYGYSMTRPDALVCWEAQFGDFANGAQSVVDEYISSGEQKWGQHSGVVLLLPHGYEG
QGPDHSSARIERYLQLCAQDNMTVVYPTTPANYFHLLRWQVLSGRHKPLIVFTPKSLLRL
KAATSPVAEITGGAFQPVIPESDPAVDPAGVRRVLLTTGKIYYDVVKARQAAGANDTAVV
RVERLYPPPVDEIKAELAKYPADVEIVWVQDEPANMGAWPFMALKLPRHIEGLKMSRVSR
PASSSPAVGSAKLHQAEQEALLARLFGEQK
NT seq
3693 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgacagagtcgtcgcatactagtgccgacccgatgctgaccgatttcggcgccaac
gagtggctggtcgacgagctgtaccagaagtacctcgacgaccccaactccgttgacgaa
gcctggtggaacttcttcgcggactaccagccggacagccggcctgcgtccgccaccccc
caggccgacggcgcggccccgacggccgccaacggctcggcggccgctccgccgacaccg
cggccaccgtccgcgccgccgaaggctccggccaaggctccggcccccaagggggacagg
ccggcgcctccgccggtcccggcgggcgccgaggaggtccggctgcgcggcgtcgccgcc
cggacggccagcaacatggaggccagcctcgccgtgccgacggcgaccagcgtgcgcgcc
gtcccggcgaagctgctgatcgacaaccgcatcgtcatcaacaaccacctcaagcgcggg
cgcggcggcaaggtctccttcacgcacctgatcgggtacgcgatcgtcagggcgctggcc
tcgatgcccgagatgaacgccgcgttcaccgaggtggacggcaagccggtgctgatcagg
ccggagcacgtcaacttcgggctggccatcgacctgcagaagggcgacggctcgcgccag
ttggtggtgccgagcatcaaggccgccgagacgctggacttccgccagttctgggcctcc
tatgaggagatcgtccgcaaggcccgcggcggcaagctcaccctggaggacttccagggc
accacgatcagcctgaccaacccgggcacgatcggcaccgtccactcggtgccgcggctg
atgcccggccagggcacgatcatcggcgtcggcgccatggagtacccggccgagttcgcg
ggcgcgtccagcgacaccctggcccgcatggggatcagcaaggtgatgacgctgacctcc
acctacgaccaccggatcatccagggcgcgcagtccggcgacttcctgcgccgcatcaac
cagctgctgctcggcgaggacggcttctacgacgagatcttcgaggcgctgcgcatcccg
tacgagccggtgcgctgggtcaaggacatctccgccacccacgaggacgacgtcgccaag
gtcgcccgcgtgcacgagctgatccacgcctaccgggtccggggccacctcatggccgac
accgacccgctggagtacaagcagcgccgccaccccgacctcgacatcctcaagcacggc
ctcaccctgtgggacctggagcgcgagttcgcgaccggcgggttcggcggcaagccgacg
atgaagctgcgcgacatcctcggcgtgctgcggatggcgtactgccggacggtcggcatc
gagtacatgcacatccaggaccccgaggagcgcgcctggatccaggagcgcgtcgaggtc
ccgcacgagaagccctcgcgcgaggagcagctgcacgtgctgcggcggctgaacagcgcc
gaggccttcgagacgttcctgcagacgaagttcgtcgggcagaagcggttctccctggag
ggcggcgagtcggtcatcccgctgctcgactcggtgatctcggcggcggccggggccagc
ctggacgaggtcgtgatcggcatggcgcaccgcggccggctgaacgtcctcgccaacatc
gtcggcaagtcctacgggcagatcttcggcgagttcgagggcaacctcgacccgcgcagc
gcccagggctcgggcgacgtgaagtaccacctcggggcgtccggcgacttcgtcggcagc
gacggctccaagatccacaccgagctggtcgcgaacccctcccacctggagacggtcgac
ccggtgctggagggcgtcgtccgcgccaagcaggacctgctggacgtcggtgaggccggc
ttcaccgtgctgccgatcctgatccacggcgacgccgcgttcgccgggcagggcgtggtg
gccgagacgctgaacctgtcgcagctgcgcggctaccgcaccggcggcagcgtgcacgtg
atcatcaacaaccaggtggggttcaccaccgcgccggagtactcgcgctccagcgtgtac
gccaccgacgtggcgcggatgatccaggcgccgatcttccacgtgaacggcgacgacccc
gagatgtgcgcgcgggtggcgcggctggcgttcgagtaccggcagacgttcaagaaggac
gtcgtcatcgacatggtctgctaccggcggcgcggccacaacgagggcgagaacccctcg
ttcacgcagccgctcatgtacgacctgatcgacgccaagcggtccgtccgcaagctctac
accgaggcgctgatcggccgcggcgacatcacggtggaggaggccgagcaggcgctccgc
gactaccaggagcagctggagcgggccttcaccgagacccgcgaggccgtgaagaagccc
ctcgaaccgggctcggtcgtgaagcccgacgtcgaggagcgcatcccgatcgaccacggc
aaggccggctcggcgatcccgcaggagaccgtgaagcggatcatcgagtcccaggtcagc
ctgccggagggcttcaccccgcacccgcggctccagccgatcctgcagcgccgcgcccag
atgatcgaggacgacgcgatcgactgggcgaccggcgagctgctggcgatgggctcgctg
ctgatcgacggccacccggttcggctcgtcgggcaggacacccggcgcggcacgttcggc
cagcggcacgcggtgctcgtcgaccgcaggacgggcgaggagtacacgccgctcaagcag
ttcgggcagggcgtctcgaagttctacgcgcacgactcgctgctcagcgagtacgcggcg
atgggcttcgagtacggctactcgatgacccgccccgacgcgctcgtgtgctgggaggcc
cagttcggcgacttcgccaacggcgcccagtcggtggtggacgagtacatctcctccggc
gagcagaagtggggccagcactcgggcgtcgtgctgctgctgccgcacggctacgagggc
caggggcccgaccactcgtccgcgcggatcgagcggtacctgcagctgtgcgcgcaggac
aacatgaccgtcgtctacccgaccacgccggcgaactacttccacctgctgcgctggcag
gtcctgtcggggcggcacaagccgctgatcgtgttcacgccgaagtcgctgctgcggctg
aaggcggccacgtccccggtcgcggagatcaccggcggtgcgttccagccggtcatcccg
gagagcgacccggcggtcgacccggcgggcgtgcggcgggtgctgctcaccaccggcaag
atctactacgacgtggtgaaggcccggcaggccgcgggcgccaacgacaccgcggtcgtg
cgggtcgagcggctctacccgccgccggtcgacgagatcaaggcggagctggccaagtac
ccggccgacgtcgagatcgtctgggtgcaggacgaacccgccaacatgggcgcctggccg
ttcatggcgctgaagctgccgcgccacatcgaggggctgaagatgtcgcgggtgtcgcgc
ccggcgtcctcgtccccggcggtgggctcggcgaagctgcaccaggcggagcaggaggcg
ctgctcgcgcgcctgttcggcgagcagaagtag
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