Actinomadura citrea: OG979_30020
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Entry
OG979_30020 CDS
T09741
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
acir
Actinomadura citrea
Pathway
acir00010
Glycolysis / Gluconeogenesis
acir00020
Citrate cycle (TCA cycle)
acir00620
Pyruvate metabolism
acir00785
Lipoic acid metabolism
acir01100
Metabolic pathways
acir01110
Biosynthesis of secondary metabolites
acir01120
Microbial metabolism in diverse environments
acir01200
Carbon metabolism
acir01210
2-Oxocarboxylic acid metabolism
Module
acir_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
acir00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
OG979_30020 (aceE)
00020 Citrate cycle (TCA cycle)
OG979_30020 (aceE)
00620 Pyruvate metabolism
OG979_30020 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
OG979_30020 (aceE)
Enzymes [BR:
acir01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
OG979_30020 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transket_pyr
Radical_SAM
Motif
Other DBs
NCBI-ProteinID:
WUR56658
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Position
complement(6456923..6459682)
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AA seq
919 aa
AA seq
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MSDGLPSQLPDINPDETREWLESLDTVIKTEGRGRARYVMLRLLERARELQVGVPGLRST
DFINTIPPESEPWFPGDEHVERRIRAYIRWNAAIMVSRANRPELGVGGHIATYASAASLY
EVGFNHFFRGKDHGESGDQVFIQGHAAPGIYARAFLEGRLPEDKLDGFRQEHSHPGGGLS
SYPHPRLMPDFWEFPTVSMGLTAIDSVYQARFNRYLYNRKIKDTSRSHVWAFLGDGEMGE
PESLGAIGLAAREELDNLTFVVNCNLQQLDGPVRGNGKIIQELESFFRGAGWNVIKVIWG
RDWDPLLAQDVDGVLVNQMNTTPDGQFQTFSVESGEYIREKFFGDDPRLRKIVQHLSDDD
LRKLSRGGHDYRKVYAAFKSAREHVGQPTVILAHTIKGWTLGSDFEARNATHQMKKLTKA
ELKEFRDRLYLDIPDSALEAPLPPYYHPGEDSEEIQYMRERRAALGGFLPKRVVRAKTLK
LPGDPVYSELKKGSGKQNIATTMAFVRLLKDLIKDENIGARFVPIAPDEYRTFGMDSLFP
TSKIYSPHGQTYDAVDRKLLLSYKEAESGQMLHEGISEAGSMASTIAAATAYATHGEHMI
PVYIFYSMFGFQRTGDQMWALGDQMGRGFLLGATAGRTTLTGEGLQHADGHSPLLAASNP
ACVHYDPTWAFELAHIVKDALRRMYGSSEEHPNGEDVFYYLTVYNEPYQQPAEPENLDVD
GLLKGLYRHRAAPEVSSGNGQAPRAQILASGVGGRWALEAQRLLAEDWGVAADVWSATSW
NELAREARECDDWNLLNPDAEQRVPYVSRTLDNVAGPIVAVSDYMRAVPDQIAPWVHGDY
TSLGTDGFGFSDTRAAARRFFNVDAASIVLAVLTRLARHGEVKPETLAEAIQRYQLDSAV
SDVFAGGVGSAESNTGGDA
NT seq
2760 nt
NT seq
+upstream
nt +downstream
nt
atcagcgacgggctgccgagccagctgcccgacatcaacccggacgagacccgggagtgg
ctggagtcgctggacacggtcatcaagaccgagggccgcggcagggcgcgctacgtgatg
ctgcggctgctggagagggcgcgagaactgcaggtcggggtacccggcctgcgcagcacc
gacttcatcaacacgatcccgccggaatccgagccctggttccccggcgacgagcacgtg
gagcggcgcatccgcgcctacatccggtggaatgccgcgatcatggtgtcgcgggcgaac
cgccccgaactcggcgtcggcggccacatcgccacctacgcctccgcggcctcgctctac
gaggtgggcttcaaccacttcttccgcggcaaggaccacggcgagtccggcgaccaggtg
ttcatccagggccacgcggcgcccggcatctacgcgcgcgcgttcctcgagggacggctg
cccgaggacaagctcgacgggttccgtcaggagcactcgcaccccggcggcggcctgtcg
tcctacccgcacccgcggctcatgccggacttctgggagttccccacggtctccatgggc
ctgaccgcgatcgactcggtttaccaggcccggttcaaccggtacctgtacaaccgcaag
atcaaggacacgtcccgctcgcacgtgtgggcgttcctcggcgacggcgagatgggcgag
ccggagtcgctcggcgcgatcggcctcgccgcccgcgaggagctcgacaacctcaccttc
gtcgtcaactgcaacctccagcagctcgacggcccggtgcgcggcaacgggaagatcatc
caggagctggagtcgttcttccgcggcgccggctggaacgtcatcaaggtcatctggggc
cgcgactgggacccgctgctcgcgcaggacgtcgacggcgtcctggtcaaccagatgaac
accacccccgacggccagttccagacgttctccgtcgagtccggcgagtacatccgggag
aagttcttcggcgacgacccgcggctgcgcaagatcgtccagcatctgtcggacgacgac
ctgcgcaagctgtcgcgcggcgggcacgactaccgcaaggtgtacgcggcgttcaagtcg
gcccgcgagcacgtcgggcagccgaccgtgatcctcgcgcacaccatcaagggctggacg
ctcggctcggacttcgaggcccgcaacgccacccaccagatgaagaagctcaccaaggcc
gagctgaaggagtttcgggaccgcctttacctggacatcccggactcggcactggaggcg
ccgctgccgccctactaccacccgggcgaggactccgaagagatccagtacatgcgcgag
cggcgcgccgccctcggcgggttcctgccgaagcgggtcgtgcgggccaagacgctcaag
ctgcccggcgaccccgtctacagcgagctgaagaaggggtccggcaagcagaacatcgcg
acgaccatggcgttcgtccggctgctcaaggacctgatcaaggacgagaacatcggcgcc
cggttcgtcccgatcgccccggacgagtaccgcacgttcggcatggactcgctgttcccc
acgtccaagatctactcgccgcacgggcagacctacgacgccgtggaccgcaaactgctg
ctgtcgtacaaggaggccgaaagcggccagatgctccacgagggcatcagcgaggcgggc
tcgatggcctccaccatcgcggccgccaccgcctacgccacgcacggcgagcacatgatc
ccggtctacatcttctactcgatgttcgggttccagcggaccggcgaccagatgtgggcg
ctcggcgaccagatgggccgcgggttcctgctcggcgcgaccgccggccgcaccacgctc
accggtgagggcctccagcacgcggacggccactcccccctgctcgcggcgtccaacccc
gcgtgcgtccactacgacccgacgtgggccttcgagctcgcccacatcgtcaaggacgcc
ctgcgccgcatgtacgggtcgtccgaggagcacccgaacggcgaggacgtcttctactac
ctcaccgtctacaacgagccgtaccagcagcccgccgaacccgagaacctcgacgtcgac
gggctcctcaagggcctgtaccggcaccgggccgccccggaggtctcctccgggaacggc
caggccccgcgcgcgcagatcctcgcctccggcgtcggcggccggtgggccctcgaggcg
cagcggctgctcgccgaggactggggcgtcgccgcggacgtgtggtcggccacgtcgtgg
aacgagctggcccgcgaggcccgcgagtgcgacgactggaacctgctgaaccccgacgcc
gagcagcgcgtcccgtacgtcagccggacgctcgacaacgtcgccgggccgatcgtcgcg
gtgtcggactacatgcgcgccgtacctgaccagatcgcgccctgggtgcacggggactac
acctcgctcggcacggacgggttcggattctccgacacccgcgccgccgcccgccgcttc
ttcaacgtggacgccgcgtcgatcgtcctcgcggtgctcacccgcctcgcccgccacggc
gaggtcaagccggagaccctggcggaggcgatccagcgctaccagctggactccgccgtc
agcgacgtcttcgcgggcggcgtcggcagcgccgagagcaacaccggcggcgacgcttga
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