Arcobacter cloacae: ACLO_0134
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Entry
ACLO_0134 CDS
T06845
Symbol
metH
Name
(GenBank) cobalamin-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
aclo
Arcobacter cloacae
Pathway
aclo00270
Cysteine and methionine metabolism
aclo00450
Selenocompound metabolism
aclo00670
One carbon pool by folate
aclo01100
Metabolic pathways
aclo01110
Biosynthesis of secondary metabolites
aclo01230
Biosynthesis of amino acids
aclo04981
Folate transport and metabolism
Module
aclo_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
aclo00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
ACLO_0134 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
ACLO_0134 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
ACLO_0134 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
ACLO_0134 (metH)
04980 Cobalamin transport and metabolism
ACLO_0134 (metH)
Enzymes [BR:
aclo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
ACLO_0134 (metH)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding
B12-binding_2
CdhD
Motif
Other DBs
NCBI-ProteinID:
QKF88678
LinkDB
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Position
135477..138956
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AA seq
1159 aa
AA seq
DB search
MLETIKNLIEKKVLIIDGAMGTQLQLAQIKQEEWLFEDKDLEGCNELLNLTAPHVLEKIH
DDYALAGADLICTNTFGSMPWVLDEYDIGHMSYELSRLGASLVKKSCEKYSTKEKPRFVV
ASIGPGTKLPSLGHIKYDEMYEGYKIMAKGLVDGGTDIFLLETCQDPLQIKAALHALNDT
APQIPIMVSVTIELSGTMLIGTDAMTIAAIMAPFNILSLGFNCGTGPVQVHKHIKTLSQV
CKFPISVHANAGLPQNRGGKTYYPMQPEEFTKLTKEFLQINGVSFLGGCCGTTPAHIEAL
AKAVEKEVPLKPCGFLKASLASLFGTVPLKQEPAPLLIGERSNATGSKAFRELLKANDYE
GTLSVGQQQVRAGAHVIDVSVGFAGRDERADMDAVTALYSQKVALPLMPDSTQIYALEAA
LKQIGGRAIINSVNLEDGEEKFDAVCSLAKKFGAALVCLVIDEIGMAKTVERKLEVAERI
YDLCVNRHGFDPNDLVFDMLTFTIGSGDDEYRNAGIDTLEAIREFQIRHPEVGTTLGLSN
ISFGLSTDARIYLNSIYLDHCVKAGLTSAIVNVKHILPLNKISPEDRKACDNLIFNIWEN
GADPLFAFIEHFSNVGAQEEQSDEEYQKLEPIEKVKKLLLDGDKDRLIPLALELKDSVNP
EIIVNEWLIDGMKIIGELFGSGQMQLPFVLQSAETMKATVDALNPYLPKQEKASETTLIL
GTVKGDVHDVGKNLVDIILSNNGFKVVNIGIKAGLDTFVEKLQEHNAHAIGMSGLLVKST
AVMKENLEELQKLGIKVPVLLGGAALTKNFIDEYCRPYYDGPIFYCRDAFDGVVSMQRIE
KGDANNTALAADLIQIIDTSDRVEEEVVEIPPYEEITMPQRGKFVFPPIWDRIARTGKKL
DKELIFKWINHRVLFRQRWGYKRGKQDSQAFLKYEKDVVEPTYEALKAELVDKDIFDPIA
IYAYYPCISHDNKLYIFDRKYLFNTLEESKNVPLLSEAIKVLEFPRQKRKPFRCIADFFA
NDRLDVVAFTLASAGLKISDYERSLYDKGEFTKYYQVHGLGVELAEALAEVLHKQIRLDL
DIVPKEGHTLNDVQMKQYVGCRYSPGYAACPDLAMNRDIFDLLNPEEFGIELSETFQMHP
EQTTCAIVVTNPEANYYNI
NT seq
3480 nt
NT seq
+upstream
nt +downstream
nt
atgttagaaacaataaaaaatttgattgaaaaaaaagttttgattatagatggagctatg
ggaacacagcttcaattagcacaaataaaacaagaagagtggttatttgaagataaagat
ttagaaggttgtaatgaacttttaaatcttactgctccccatgttttagaaaaaatacat
gatgattatgcacttgcaggtgctgatttgatatgtacaaatacctttggttcgatgcct
tgggttttagatgagtatgacataggtcatatgtcttatgaactatcacgtttaggagct
agtttagtaaaaaaatcttgtgaaaaatatagcacaaaagagaaaccaagatttgtagta
gcttcaattggtccaggaacaaaacttccatcacttggtcatattaaatatgatgagatg
tatgagggttataaaatcatggctaaaggattagttgatggtggaactgatatattttta
cttgaaacttgccaagacccacttcaaataaaagcagcacttcatgctctaaatgacaca
gcaccgcaaattcctattatggtatccgttactattgagttaagtggtactatgttaata
ggaactgacgctatgacaatagctgctattatggcaccttttaatatcttatctttaggg
tttaattgtggaacaggacctgttcaagttcataaacatataaagactttaagtcaagtt
tgtaagtttcctatttcagttcatgcaaatgcgggacttcctcaaaatagaggtggaaaa
acttattatccaatgcaaccagaagagtttacgaaacttacaaaagagtttttacaaatc
aatggagttagttttcttggtggttgttgtggaacaacacctgcacatatagaagctttg
gcaaaggcagttgaaaaggaagttccactaaagccttgtgggtttttgaaagcttcattg
gcttcactttttggaacagttcccttaaaacaagaaccagcacctttacttataggtgag
cgttcaaatgcaacaggaagtaaagcttttagagagctattaaaagcaaatgattatgag
ggaactttaagtgttggacaacaacaagtacgtgcaggggctcacgtaattgatgtatca
gttggatttgctggtcgtgatgaaagagccgatatggatgctgttactgcactttattct
caaaaagtagcacttccattgatgccagattctacacaaatttatgctcttgaagctgca
cttaaacaaataggtggaagagcaattataaactctgtaaatttagaagatggtgaagaa
aaatttgatgcggtttgttctttggctaaaaaatttggagcagctttagtttgtttggtt
attgatgaaattggaatggcaaaaacagtagagagaaaactagaagttgctgagcgaatc
tatgatttatgtgtaaatagacacggttttgacccaaatgatttagtatttgatatgctt
acttttactattggaagtggagatgatgaatatagaaatgctggaattgatacccttgaa
gcaataagagagtttcaaattagacatccagaagttggaactactttaggtttatcaaat
atctcttttggattaagtacagacgctagaatttatttaaattctatctatcttgaccat
tgtgtaaaagctggattaacaagtgctattgtaaatgtaaaacatatattaccactaaat
aaaataagtcctgaagatagaaaagcttgtgataatttgatttttaatatttgggaaaat
ggtgctgatccattatttgcttttattgaacatttctcaaatgttggtgcgcaagaagaa
caaagtgatgaagagtatcaaaaacttgaaccaattgaaaaagtaaaaaaacttcttctt
gatggagataaagatagattgattcctttagctttagagttaaaagatagtgttaatcct
gaaattatagtaaatgaatggttaattgatgggatgaaaattattggagagttatttggt
agtggtcaaatgcagttaccatttgtacttcaaagtgctgaaactatgaaagcaactgtt
gatgcacttaatccatatttaccaaaacaagagaaagcaagtgaaacaacactaattctt
ggaactgtaaaaggtgatgttcatgatgttggtaaaaacttagttgatattattttaagt
aataacgggtttaaagttgtaaatattggtataaaagctggtttagatacttttgttgaa
aaacttcaagaacataatgctcatgcaattggaatgagtggattacttgtaaaaagtaca
gctgttatgaaagaaaatcttgaagagttacaaaaactaggaattaaagttcctgtactt
ttaggtggtgcagctttaactaaaaactttattgatgagtattgtagaccatattatgat
ggtccgattttttattgtagagatgcctttgatggtgttgtttctatgcaaagaattgaa
aagggtgatgctaataacactgcacttgcagctgatttaattcaaattattgatacaagt
gatagggttgaagaagaggttgttgaaattccaccttatgaagagattactatgccacaa
cgtgggaaatttgtcttccctccaatttgggatagaatcgctagaactggtaaaaaactt
gataaagagttgatttttaagtggataaatcatagggttttatttagacaaagatgggga
tataaaagaggtaaacaagactcacaagcttttttaaaatatgaaaaagatgtggttgag
ccaacttatgaggctttaaaagctgagttagttgataaagatatttttgacccaattgct
atttatgcttattatccttgtatttcccatgataataaactttatatttttgatagaaaa
tatctatttaatacacttgaagagtcaaaaaatgtaccacttttgagtgaagctataaaa
gtattagagtttccaagacaaaaaagaaaaccatttagatgtatagctgatttttttgca
aatgatagacttgatgtggttgcctttacacttgcaagtgctggtcttaaaatttctgat
tatgaaagaagtctatatgataaaggtgaatttacaaaatattatcaagttcatggactt
ggtgttgaacttgctgaagcactagctgaagttttacataaacaaataagacttgattta
gatatagtgccaaaagagggacatactttaaatgatgttcaaatgaaacaatatgtaggt
tgtcgatattctcctggatatgctgcttgtcctgatttggctatgaatagagatattttt
gatttattaaatcctgaagagtttggaatagaattatctgaaacattccaaatgcatcct
gagcaaactacttgtgcgatagtggttactaatcctgaggcaaattattataatatataa
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