Actinoplanes sp. OR16: ACTI_12900
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Entry
ACTI_12900 CDS
T10317
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
acte Actinoplanes sp. OR16
Pathway
acte00020
Citrate cycle (TCA cycle)
acte00630
Glyoxylate and dicarboxylate metabolism
acte00785
Lipoic acid metabolism
acte01100
Metabolic pathways
acte01110
Biosynthesis of secondary metabolites
acte01120
Microbial metabolism in diverse environments
acte01200
Carbon metabolism
acte01210
2-Oxocarboxylic acid metabolism
Module
acte_M00009
Citrate cycle (TCA cycle, Krebs cycle)
acte_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
acte00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
ACTI_12900 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
ACTI_12900 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ACTI_12900 (kgd)
Enzymes [BR:
acte01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
ACTI_12900 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
ACTI_12900 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
ACTI_12900 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
ACTI_12900 (kgd)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
BBH64605
UniProt:
A0A3T1AP70
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All DBs
Position
1420793..1424545
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AA seq
1250 aa
AA seq
DB search
MMTNTVKEANAAVSTQQTSQDNPLADFGPNEWIVDEMYQRYLADPTSVDPAWHDFFADYK
PAMASGSIATPDEAKAATATASAAKAGTDAPAAATVAPPKPVTPPPPAAEAKPKPAPVEK
TAPKPSPNGTAPAEAKTTPLRGVASKIVQNMSASLEVPTATSVRAVPAKLMVDNRIVINN
HLSRGRGGKVSFTHLIGWALIRATVQHPEMNNSFAEIDGKPNLVQPAHINLGIAIDLAKK
DGTRTLVVPSIKNCETLDFRGFWQAYEDVVRRARRNELTMDDYAGTTISLTNPGGIGTVH
SIPRLMNGQSAIIGVGAMEYPAPYAGMSDEMLTELGVSKVTTLTSTYDHRVIQGAQSGEF
LKVMHELLLGNHGFYDEIFTSLRIPYEPVRWVRDVARTSEGQIDKAARVVELIHAYRVRG
HLMADTDPLEFTIRKHPDLDVLQHGLTLWDLDRTFPVGGFAGKQKMKLRDVLGVLRDSYC
RRVGIEYMHIQDPEERRWVQERIEVKYTKPDTDEQKHILHRLNAAEAFETFLQTKFVGQK
RFSLEGGESLIPLLDAVLQSSAEAGLDEMVIGMAHRGRLNVLTNIVGKPYEKIFNEFEGQ
MDPKSAHGSGDVKYHLGQTGKYTTPDGENSTTVSVVANPSHLEAVDPVLEGIVRAKQDRL
DLGLHGYTVLPVLVHGDAAFAGQGVVAETLNLSQLRGYRTGGTVHVIVNNQVGFTTAPEY
SRSSMYSTDVARMIQAPIFHVNGDDPEAVVRVAKLAFEYRQTFNKDVVIDMICYRRRGHN
EGDDPSMTNPRMYQIIDKKRSVRKAYTEELIGRGDITVQEAEEQLRDYQGRLEDVFKATR
DSAGTPPRPRIIAEEGEPAVETAVETSVVHAVGQAHIELPEGFTPHKRVQQLLDRRAKMS
TDGGIDWGFGELIAFGSLLNQGVTVRLAGQDSRRGTFTSRHAAIVDAKTGKDFLPISTLT
TGNARFFVHDSLLSEYAAMGFEYGYSVENPDALVLWEAQFGDFVNGAQSIVDEFLSSGEV
KWGQQSSLVLLLPHGMEGQGPDHSSGRPERFLQLCAQDNMRVANPTTPANYFHLLRRQAL
SSKRKPLVVFSPKSLLRHKLAVSAVSDFTEGTFQPVLADAGVNGTQLDASAVKRVLLCSG
KVYYDLFQARAERGITDTAIIRMEQIYPLPVEELKALLSQYPNAEDFAWVQEEPANQGAW
SFVALNLLEHLEGVRLRRISRPAAAAPAVGSAKMHDAEQAALIEASLPRT
NT seq
3753 nt
NT seq
+upstream
nt +downstream
nt
gtgatgacaaacacggtgaaagaggcgaacgcggcagtgtcgacgcagcagacttcgcag
gacaatccgctcgcggacttcggtcccaacgagtggatcgtcgatgagatgtaccagcga
tacctggccgacccgaccagtgtcgaccctgcctggcacgacttcttcgccgactacaag
ccggcgatggcatcgggctcgatcgcgacgccggacgaggccaaggcggccaccgcgacg
gcttccgcagccaaagccggtacggacgcgccggccgcggccacggtcgccccgcccaag
ccggtgaccccgcccccgccggccgccgaggccaagccgaagcccgccccggtggagaag
accgcgcccaagccgtcgccgaacggcaccgcgccggccgaggcgaagaccaccccgctg
cgcggcgtcgcctccaagatcgtgcagaacatgtcggcctcgctggaggtcccgaccgcg
acgtcggtgcgcgccgtcccggccaagctgatggtcgacaaccgcatcgtcatcaacaac
cacctctcccgcggccgtggtggcaaggtcagcttcacccacctgatcggctgggcgctg
atccgcgcgacggtgcagcacccggagatgaacaactccttcgccgagatcgacggcaag
cccaacctggtgcagccggcgcacatcaacctcggcatcgcgatcgacctcgccaagaag
gacggaacccgcacgctcgtggtgccgtccatcaagaactgcgagaccctcgacttccgt
ggcttctggcaggcctacgaggacgtcgtccggcgggcccgccgcaacgagctgaccatg
gacgactacgccggcaccacgatctcgctgaccaaccccggcggcatcggcaccgtccac
tccatcccccgcctgatgaacgggcagagcgccatcatcggcgtcggcgccatggagtac
cccgctccgtacgccgggatgagcgacgagatgctgaccgagctgggcgtgagcaaggtc
accacgctcaccagcacctacgaccaccgggtcatccagggcgcgcagtccggcgagttc
ctcaaggtcatgcacgagctgctgctcggcaaccacggcttctacgacgagatcttcacc
tcgctgcggattccgtacgagccggtccgctgggtgcgcgacgtggcccgcacctccgag
ggccagatcgacaaggcggcccgggtcgtcgagctgatccacgcctaccgcgtgcgcggt
cacctgatggccgacaccgacccgctcgagttcaccatccgcaagcaccccgacctcgac
gtcctgcagcacggcttgaccctgtgggacctggaccggaccttcccggtcggcgggttc
gcgggcaagcagaagatgaagctgcgcgacgtcctcggcgtgctgcgggacagctactgc
cgccgcgtcggcatcgagtacatgcacatccaggaccccgaggagcgccgctgggtccag
gagcgcatcgaggtcaagtacacgaagccggacaccgacgagcagaagcacatcctgcac
cggctcaacgcggccgaggcgttcgagaccttcctgcagaccaagttcgtcggccagaag
cggttctcgctggagggcggcgagtcgctgatcccgctgctcgacgcggtgctgcagtcg
tcggccgaggcaggtctcgacgagatggtgatcggcatggcccaccgcggccggctgaac
gtgctcaccaacatcgtcggcaagccgtacgagaagatcttcaacgagttcgagggtcag
atggacccgaagtcggcccacggctccggtgacgtcaagtaccacctcggccagaccggg
aagtacacgacgcccgacggcgagaactcgacgaccgtcagcgtggtggcgaacccgtcg
cacctggaggcggtcgacccggtcctcgagggcatcgtccgcgccaagcaggaccgcctc
gacctgggcctgcacggctacacggtcctcccggtgctggtgcacggcgacgccgcgttc
gccggccagggcgtggtcgccgagacgctcaacctctcccagctgcgtggttaccggacc
ggtggcacggtgcacgtcatcgtgaacaaccaggtcggcttcaccaccgccccggagtac
agccgctcctcgatgtactcgaccgacgtggcccggatgatccaggccccgatcttccac
gtgaacggcgacgaccccgaggccgtcgtccgggtcgcgaagctcgccttcgagtaccgc
cagacgttcaacaaggacgtcgtgatcgacatgatctgctaccgccgccgcggtcacaac
gagggcgacgacccgtcgatgaccaacccgcggatgtaccagatcatcgacaagaagcgc
agcgtgcggaaggcgtacaccgaggagctcatcggccgcggcgacatcaccgtccaggag
gcggaggagcagctgcgcgactaccagggccgcctcgaggacgtcttcaaggccacccgg
gactccgccggcaccccgccccgcccgcgcatcatcgcggaggagggcgagcccgcggtg
gagaccgctgtcgagacgagcgtggtgcacgcggtcggccaggcgcacatcgagctgccc
gagggcttcaccccgcacaagcgggtgcagcagctcctcgaccggcgcgccaagatgtcc
accgacggcggcatcgactggggcttcggtgagctgatcgcgttcggctcgctgctcaac
cagggcgtcacggtccggctggccggtcaggactcccgccgcggcacgttcacctcgcgg
cacgccgcgatcgtcgacgcgaagaccggcaaggacttcctgccgatctccacgctgacc
accggcaacgcccggttcttcgtccacgactcgctgctcagcgagtacgccgcgatgggc
ttcgagtacggctactcggtggagaacccggacgctctggtcctctgggaggcccagttc
ggcgacttcgtcaacggcgcccagtcgatcgtggacgagttcctctcctccggcgaggtg
aagtggggccagcagtcgtcgctggtgctgctgctcccgcacggcatggagggccagggc
ccggaccactcgtccggccgcccggagcggttcctgcagctctgcgcgcaggacaacatg
cgggtggcgaacccgaccaccccggcgaactacttccacctgctgcgccgccaggccctg
agcagcaagcgcaagccgctggtggtcttctcgccgaagtcgctgctccggcacaagctg
gcggtctccgcggtgagcgacttcaccgagggcaccttccagccggtgctcgccgacgcc
ggcgtcaacggcacgcagctcgacgcctcggcggtgaagcgggtcctgctctgctccggc
aaggtctactacgacctgttccaggcccgggccgagaggggcatcaccgacacggcgatc
atccggatggagcagatctacccgctgcccgtcgaggagctgaaggcgctgctctcgcag
tacccgaacgccgaggacttcgcctgggtccaggaggagccggccaaccagggcgcttgg
tcgttcgtggcgctcaacctgctcgagcacctggagggcgtccgcctgcggcggatctcc
cgcccggccgccgccgccccggcggtcggttcggccaagatgcacgacgccgagcaggcc
gcgctgatcgaggcgtcgctgccgcgcacgtga
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