KEGG   Actinomyces sp. HMT897: JJJ15_00145
Entry
JJJ15_00145       CDS       T10470                                 
Name
(GenBank) proline dehydrogenase family protein
  KO
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
Organism
acth  Actinomyces sp. HMT897
Pathway
acth00250  Alanine, aspartate and glutamate metabolism
acth00330  Arginine and proline metabolism
acth01100  Metabolic pathways
acth01110  Biosynthesis of secondary metabolites
Module
acth_M00970  Proline degradation, proline => glutamate
Brite
KEGG Orthology (KO) [BR:acth00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    JJJ15_00145
   00330 Arginine and proline metabolism
    JJJ15_00145
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:acth03000]
    JJJ15_00145
Enzymes [BR:acth01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.88  L-glutamate gamma-semialdehyde dehydrogenase
     JJJ15_00145
  1.5  Acting on the CH-NH group of donors
   1.5.5  With a quinone or similar compound as acceptor
    1.5.5.2  proline dehydrogenase
     JJJ15_00145
Transcription factors [BR:acth03000]
 Prokaryotic type
  Ribbon-helix-helix
   Other families
    JJJ15_00145
SSDB
Motif
Pfam: Aldedh Pro_dh
Other DBs
NCBI-ProteinID: QQO77851
UniProt: A0A974NA84
LinkDB
Position
33067..36630
AA seq 1187 aa
MKAPVSGPTCPPSARERRCPDHLWDLGLKAVERARRWADESVNEPTPRTARLLSSVLADP
EGLGFTTRFVDDVVRPADLDVAAAALTRLAAGRTDFLPVPLAAAMGLGGAAARLAPRAVA
AVARRTFRELVGDLVVDATDRGLGPALARLRAGGNRLNVNLLGEAVLGEREAARRLAEVS
RLVTREDVDYVSVKVSAVTGPHNPWGFTEVVAHGVEALSPLYRLARDHGTFVNLDMEDYK
DLDLTLAVFTGILDQEDLRDYEAGVVLQAYLPDSPAAMERLQAWAARRVAGGGARVKVRV
VKGANLSMERVDAEIHGWELTTWPTKQATDTNYKRMLTWAMTPERTANVRLGVAGQNLFD
IAFAYELRAARLEEADAVEFEMLSGMATDLAEVVRRDVGHLLLYVPVVHPHEFDVAVSYL
VRRLEENAAPANFMSGVFSLATDGSVFARERDRFLASLADLDPGAPSPAPRRVQDRLAEA
GAGVPEPTGSLEERSSRPFASTPDSDPSLEANRRWARGIAEAVPTSTRGAQAVQDAQGAW
ATTADVDAVLASVARAAADWAALGARERAAVLHHAGDVLAARRGELIEVAASEAGKTIDQ
ADPEVSEAIDFCHHYAAAALDLEDPAYLVGARFEPVAVTVVASPWNFPLAIPVGGTVAAL
ATGSGVVLKPAPPARRCAAELVRALHDAGVPADVLVLAPVEDGEVSRHLVTHPGVGRVVL
TGSYDTARLFRSWRPDMHLLGETSGKNAIVVTPSADPDLAVRDVVASAFAHAGQKCSAAS
LLVLVGSAGRSARLARQLVDATASLRVLGPAHLDSQVGPAVVPDDPKALRGLTTLGPGER
WVLEPRYLGGGLWRPGIRVGVAPGSEFHLTEYFAPVLGVMRVETLQEAVDVVNAVDYGLT
SGLQTLDRDELATWLEGVQAGNLYVNRGITGAIVRRQPFGGWKRSAIGATTKAGGPSYLL
GLGEVVAADAAPPGAGDLRAHLDGGVRAVYDAVRSGLGREDSVFLHQALLADAEAWENAY
GRSRDVGALVCERNVLRYRPTAVVVRAEAGTHLADLVRVLAAGVRAAGPLSLSVAEPLPP
ELGAALTGAGVVVAVERGRVWSARLADTAACGPQGARVRILGPRTQSARERWEQACRATS
GSPDVALYTGAVTACPHTELLPFLREQAVSVTAHRFGTPLDLAAGLL
NT seq 3564 nt   +upstreamnt  +downstreamnt
atgaaggcccccgtctccggccccacctgtccgccctccgcccgggagcgccgctgcccc
gaccacctgtgggaccttggtctcaaagcagtggagcgggcccgccgctgggccgacgag
tccgtcaacgagcccacgccgcgcaccgccaggctcctgtcctccgtcctggccgacccc
gagggcctgggcttcaccacccgcttcgtggacgacgtggtgcgccccgccgacctcgac
gtggccgctgcggccctgaccaggctcgccgccgggcgcaccgacttcctgcccgtcccc
ctggccgccgccatgggcctggggggcgcggccgcccgcctggcccccagggccgtggcc
gccgtggcccgccgcaccttccgggagctggtgggcgacctcgtggtcgacgccaccgac
cggggcctgggccccgccctggccaggctgcgcgccgggggcaaccgcctcaacgtcaac
ctcctgggggaggcggtcctgggggagagggaggccgcccgccgcctggccgaggtctcc
cgcctggtcacccgcgaggacgtggactacgtctccgtcaaggtctcggccgtcaccggc
ccccacaacccctggggctttaccgaggtcgtcgcccacggcgtggaggccctcagcccc
ctgtaccgcctggcccgcgaccacggcacctttgtcaacctggacatggaggactacaag
gacctcgacctcaccctggcggtcttcaccgggatcctcgaccaggaggacctgcgcgac
tacgaggccggcgtcgtcctgcaggcctacctgcccgactccccggccgccatggagcgc
ctccaggcctgggcggcccggagggtggcgggaggcggggcccgggtcaaggtgcgcgtg
gtcaagggcgccaacctgtccatggagagggtggacgccgagatccatggctgggagctg
accacctggcccaccaagcaggccaccgacaccaactacaagcgcatgctcacctgggcc
atgacccccgagcgcaccgccaacgtgcgcctgggcgtggccgggcagaacctcttcgac
atcgccttcgcctacgagctgcgcgccgcccgcctggaggaggccgacgccgtggagttc
gagatgctctcgggcatggccaccgacctggccgaggtggtgcgtcgtgacgtggggcac
ctgctgctctacgtccccgtggtccacccccacgagttcgacgtcgccgtctcctacctg
gtgcgccgcctggaggagaacgccgcccccgcgaacttcatgtccggggtcttctccctg
gccaccgacgggtccgtgttcgcccgtgagcgcgaccgcttcctggcctccctggccgac
ctcgaccccggtgcgccctcacccgccccccgccgggtccaggaccgcctggccgaggcc
ggggccggggtgcccgagccgaccgggagcctggaggagcgctccagccgcccctttgcc
tccacccccgactccgacccgtccctggaggccaaccgccgctgggcccgtggtatcgcc
gaggccgtgcccacctccacgcgcggcgcccaggcggtccaggacgcccagggggcctgg
gccaccaccgccgacgtcgacgccgtcctcgcctccgtggcccgggccgccgccgactgg
gccgcgctgggggcccgggagcgggccgccgtcctccaccacgccggggacgtcctggcc
gcccgccgcggcgagctcattgaggtcgccgcctccgaggccggcaagaccattgaccag
gccgacccggaggtcagtgaggccattgacttctgccaccactacgcggccgccgccctg
gatctggaggaccccgcctacctggtgggggcgcgcttcgagcccgtggccgtgaccgtg
gtcgcctccccctggaacttcccgctggccatccccgtgggcggcaccgtggcggccctg
gccaccggcagcggcgtcgtcctcaagccggcgcccccggcccgccgctgcgccgccgag
ctcgtgcgggccctgcacgacgcgggcgtgcccgctgacgtcctggtcctggcccccgtg
gaggacggcgaggtctcccggcacctggtgacccacccgggtgtggggcgcgtggtcctc
accggctcctacgacaccgcccgcctcttccgctcctggaggccggacatgcacctgctg
ggggagaccagcggcaagaacgccattgtggtcaccccctcggccgacccggacctggcg
gtgcgcgacgtggtggcctccgccttcgcccacgccgggcagaagtgctcggcggcctcc
ctgctggtcctggtgggctcggcgggccgctccgcgcgcctggcccgacagctcgttgac
gccaccgcctccctgcgggtgctcggccccgcgcacctggactcccaggtcggcccggcc
gtcgtgcccgacgaccccaaggccctgcggggcctgaccaccctggggcccggtgagcgc
tgggtgctcgagccccgctacctgggtggcgggctgtggcgccccggcatccgcgtgggg
gtggcccccggcagcgagttccacctcaccgagtacttcgccccggtcctgggggtcatg
cgcgtggagaccctccaggaggccgtggacgtcgtcaacgccgtggactacgggctcacc
tcgggcctgcagacccttgaccgcgacgagctggccacctggctggagggcgtccaggcc
ggcaacctctacgtcaaccgcggcattaccggcgccattgtgcgccgccagcccttcggc
ggctggaagcgctcggcgatcggcgcgaccaccaaggccggcggccccagctacctgctg
ggcctgggggaggtcgtggccgccgacgccgccccgcccggggccggggacctgcgggcg
cacctggacggaggggtcagggccgtctacgacgccgtccgctccggcctgggccgtgag
gactccgtgttcctccaccaggcgctgctggccgacgccgaggcctgggagaacgcctac
gggcgcagccgggacgtgggcgccctggtgtgcgagcgcaacgtcctgcgctaccggccc
accgcggtggtcgtgcgggccgaggccggcacccacctggccgacctggtccgggtcctg
gcggccggcgtgcgcgccgcggggccgctgagcctgtcggtggccgagccgctgcccccg
gagctgggcgccgccctgacgggtgccggggtggtggtggccgtggagcggggccgggtg
tggagcgcccgcctggccgacacggccgcctgcggcccccagggggcgcgggtgcggatc
ctcggcccgcgcacccagtcggcccgggagcggtgggagcaggcctgccgggccacctcc
ggcagccccgacgtcgccctgtacaccggcgcggtgaccgcctgcccgcacaccgagctg
ctgcccttcctgcgtgagcaggccgtgtcggtcaccgcccaccgcttcggcaccccgctg
gacctggccgccgggctgctctag

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