KEGG   MODULE: actl_M00978
Entry
actl_M00978       Pathway   Module                                 
Name
Ornithine-ammonia cycle
Definition
K01915 K01955+K01956 K00611 K01940 K01755 (K27542,K27545)
Diagram
actl_M00978  Ornithine-ammonia cycle
actl_M00978

Class
Pathway modules; Amino acid metabolism; Arginine and proline metabolism
Pathway
actl00220  Arginine biosynthesis
actl01100  Metabolic pathways
actl01110  Biosynthesis of secondary metabolites
Organism
Actinoplanes sp. L3-i22 [GN:actl]
Gene
L3i22_014990  glnA2; type I glutamate--ammonia ligase [KO:K01915]
L3i22_015180  glutamine synthetase [KO:K01915]
L3i22_026250  glutamine synthetase [KO:K01915]
L3i22_064540  argF; ornithine carbamoyltransferase [KO:K00611]
L3i22_086830  argH; argininosuccinate lyase [KO:K01755]
L3i22_086850  argG; argininosuccinate synthase [KO:K01940]
L3i22_086880  argF; ornithine carbamoyltransferase [KO:K00611]
L3i22_087520  carB; carbamoyl-phosphate synthase large chain [KO:K01955]
L3i22_087530  carA; carbamoyl-phosphate synthase small chain [KO:K01956]
L3i22_095510  glnA4-1; glutamine synthetase [KO:K01915]
L3i22_098530  amidinotransferase [KO:K27545]
L3i22_106660  amidinotransferase [KO:K27545]
Reaction
R00253  
R00575  
R01398  
R01954  
R01086  
R13308  
Compound
C00014  Ammonia
C00064  L-Glutamine
C00169  Carbamoyl phosphate
C00327  L-Citrulline
C03406  N-(L-Arginino)succinate
C00062  L-Arginine
C00011  CO2
Reference
PMID:29632414
  Authors
Zhang H, Liu Y, Nie X, Liu L, Hua Q, Zhao GP, Yang C.
  Title
The cyanobacterial ornithine-ammonia cycle involves an arginine dihydrolase.
  Journal
Nat Chem Biol 14:575-581 (2018)
DOI:10.1038/s41589-018-0038-z
KO module
M00978
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