Actinomyces sp. zg-332: HCQ94_03905
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Entry
HCQ94_03905 CDS
T08424
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
actm
Actinomyces sp. zg-332
Pathway
actm00010
Glycolysis / Gluconeogenesis
actm00020
Citrate cycle (TCA cycle)
actm00620
Pyruvate metabolism
actm00785
Lipoic acid metabolism
actm01100
Metabolic pathways
actm01110
Biosynthesis of secondary metabolites
actm01120
Microbial metabolism in diverse environments
actm01200
Carbon metabolism
actm01210
2-Oxocarboxylic acid metabolism
Module
actm_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
actm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
HCQ94_03905 (aceE)
00020 Citrate cycle (TCA cycle)
HCQ94_03905 (aceE)
00620 Pyruvate metabolism
HCQ94_03905 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HCQ94_03905 (aceE)
Enzymes [BR:
actm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
HCQ94_03905 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
QPK93744
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Position
953524..956283
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AA seq
919 aa
AA seq
DB search
MRGCVLALFKETIPLINGLLSQIDDVDSEETQEWLDSFNALVQDKGNPRARFILLSLLQE
ARTKNIRIPSPLNTPYVNTIGVHEEAFFPGDEDLEKRIRSWIRWNAAVMVTRAQRPGIGV
GGHISSYASSAALYEVGFNHFFRGKSHPNGGDHVFFQGHVSPGMYARAFLEGRLSEKDLD
GFRQEKSQAPHGIPSYPHPRSLPDFWEFPTVSMGLGPAQAIYQAWTNKYLAMRGIKDTSA
QRVWAFLGDGEMDEPESRGMLQLAGQQGLDNLTFVINCNLQRLDGPVRGNGKIIQELEAF
FKGAGWNVIKVIWGRGWDTLLNADKDRALVHLMNECLDGDYQTFRANDGAYIRKHFFGRD
PRTARLVENWTDEQIWRDLRRGGHDYRKLYTAYKAACEHTGQPTVILAHTIKGWKLGSNF
AGRNGAHQMKKLSLDDLKHLRDRLHIPITDEQLESNPTMPPYYKPDENDEAYKYMLDRRA
KLGGFLPSRHTDATALPIPADKTFEVFKKGSGATKVASTMAFVRLLKEVIKDKEIGKYFA
PIIPDEARTFGMESLFPSAKIFNTLGQNYVPVDSEMMLSYKEAKNGQLLHTGINEAGSVA
ALQVLGTSYATNGIHMIPIYIFYSMFGFQRTADQFWAAGDQLARGFIIGATAGKTTLQGE
GTQHMDGHSHIIAGTNHAVVQYDPAYAYEIAHIFKDGLKRMYGNAEERAGRDPNVMYYLT
VYNEPIIQPAEPENLDVDGLLKGIYNISKSHPNADLQVQLMASGIALPWAEKARDILEKD
WNISAGVWSVTSWQELRREALDIDKQNWLNPTAPKKTPYLTSALQGYDGPFVATSDYDNL
LVDQISKWIPGDYYTLGADGYGFSDTRAAARRFYNIDTHSLVVKALYALAEQGKIDHAIV
EQAIQKYDLHNVNADSTKE
NT seq
2760 nt
NT seq
+upstream
nt +downstream
nt
atgagaggatgtgttttagctttgtttaaggaaacaatcccactaattaatggcttgcta
agtcaaattgacgacgtcgatagtgaagaaacacaagaatggctcgattctttcaatgcc
ttagttcaagataaaggaaacccgagagccaggtttattctattaagtttattacaagaa
gctcgtactaaaaatattcgcataccttctcctttgaatacaccttatgtaaatacaatt
ggagttcacgaagaagcctttttccctggtgacgaggacttagaaaaacgtatacgttca
tggatacgctggaacgctgctgtaatggttactagagcacaaagacctggaatcggagtt
ggtggacatatttcttcctacgcctcctctgctgctctatatgaagttggttttaaccat
ttctttagaggtaaatctcatccaaatggtggcgaccacgtatttttccaaggacacgta
agccctggaatgtacgctagagcttttctagaaggacgtttatctgaaaaagatttagat
ggattccgtcaagaaaaatctcaagctccacacggtataccatcttacccacacccacgt
tcattacctgatttctgggaatttccaactgtttctatgggactagggccagctcaagca
atctaccaagcatggactaacaagtatttagcaatgcgtggaataaaagacacatcagca
caacgcgtttgggcgttcttgggcgatggtgaaatggatgaaccagaatcacgaggcatg
ttacaactagcagggcaacaaggcttagacaacctgacttttgttatcaactgtaaccta
cagcgcctagatggtcctgtgcgtggaaatggaaaaattattcaagaacttgaagctttc
tttaaaggtgctggctggaatgttatcaaagtaatttggggacgtggctgggacacccta
ttgaacgctgataaagaccgtgcattagttcatctgatgaatgaatgcttagacggagat
taccaaacatttagagcaaatgatggagcttatattagaaagcacttctttgggcgtgat
ccacgtactgcacgtttagtggaaaattggactgatgagcaaatttggagagatctaaga
cgtggtggacacgactaccgtaaactttacacagcttataaagcagcttgtgaacacact
ggtcaaccaactgtaattttagctcacaccattaaaggctggaagttaggttcaaacttt
gctggtcgtaatggtgctcaccaaatgaagaaattatccttggatgatttgaagcattta
cgtgatcgcttacacattccgattactgatgaacaattggaatctaatccgactatgcct
ccttactacaaacctgacgaaaacgatgaggcttataaatacatgttggatcgcagggct
aaacttggaggatttttaccttcacgccatactgatgccactgccctaccaattccggca
gataaaacatttgaagtattcaaaaaaggctcaggtgcaaccaaagttgcctcaactatg
gcttttgtacgtttactaaaagaagtgattaaggataaagaaataggtaaatatttcgct
cctattatcccagatgaagctagaacatttggtatggagtctctgttccctagcgctaaa
atctttaatactctaggacaaaattatgttccagtagatagcgaaatgatgcttagctat
aaagaagcaaaaaatggtcaattgctacacactggtattaatgaagctggctctgttgct
gcactacaagtactaggaacatcatacgctacaaatggtattcacatgattcctatatac
attttctactcaatgtttggtttccaaagaacagctgatcagttctgggctgctggagac
cagcttgcacgtggtttcataatcggagcaactgctggtaaaactactttacaaggtgaa
ggtacacagcatatggatggacattcacatattattgctggtactaaccacgccgtagtg
cagtacgatccagcctatgcctatgaaattgctcatatattcaaagatggcctaaaacgc
atgtatggcaatgctgaagaaagagctggtcgtgatcctaatgtcatgtactacttgaca
gtttataacgagccgattattcaaccagccgaacctgaaaacttagacgtggatggtcta
cttaaaggtatctacaacatatctaaatcacatcctaatgctgatttgcaagtacagctt
atggcttcaggtattgctctaccatgggctgaaaaagctagagatatactcgaaaaagac
tggaatatttcagctggtgtttggtcagtaacttcttggcaagaactacgtcgcgaagct
ttggatatagataaacaaaactggctgaatccaacagcaccaaagaaaacaccatattta
acctctgcgttacaaggctatgatggtccatttgttgcgacttctgattatgataacttg
cttgtagatcaaatcagcaagtggattcctggtgactattacactcttggcgctgatgga
tacggattctctgatactcgtgcagcagctcgtcgtttctacaatattgatactcattct
ctagttgttaaagcactatatgctctagctgaacaaggcaaaattgatcacgccattgtt
gaacaagcaatccaaaaatatgatttacacaatgtaaatgctgatagtactaaagagtaa
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