Actinokineospora sp. UTMC 2448: Actkin_02486
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Entry
Actkin_02486 CDS
T08397
Name
(GenBank) Actinorhodin polyketide putative beta-ketoacyl synthase 1
KO
K05551
minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-
2.3.1.260
2.3.1.235
]
Organism
actu
Actinokineospora sp. UTMC 2448
Pathway
actu00253
Tetracycline biosynthesis
actu01056
Biosynthesis of type II polyketide backbone
actu01100
Metabolic pathways
actu01110
Biosynthesis of secondary metabolites
Module
actu_M00778
Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:
actu00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
Actkin_02486
00253 Tetracycline biosynthesis
Actkin_02486
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
actu01004
]
Actkin_02486
01008 Polyketide biosynthesis proteins [BR:
actu01008
]
Actkin_02486
Enzymes [BR:
actu01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
Actkin_02486
2.3.1.260 tetracycline polyketide synthase
Actkin_02486
Lipid biosynthesis proteins [BR:
actu01004
]
Polyketide synthase
Component type
Actkin_02486
Polyketide biosynthesis proteins [BR:
actu01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Octaketide PKS
Actkin_02486
Nonaketide PKS
Actkin_02486
Decaketide PKS
Actkin_02486
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Ketoacyl-synt_C
Thiolase_N
Motif
Other DBs
NCBI-ProteinID:
UVS78750
LinkDB
All DBs
Position
2642827..2644089
Genome browser
AA seq
420 aa
AA seq
DB search
MDRQAVVTGLGVVAPGGIGAKQFWELLTAGRTATRTISLFDATGFRSRVAAECDFDARVA
GLSHRQIRMWDRTTQFAVVAAREALADSGVADGIVPERTGVAIGTACGMTQSLDHEYAVA
SDEGRAWLVDDRHGSPYLYDYFLPSSMAVEVAWLVGAEGPVAIVPTGCTSGIDALVHAAE
LIRDGVVDVVVAGASDAPISPITAACFDAIKATTPRNDEPETASRPFDRTRNGFALAEGA
AVLVLEEGERARRRGAHVYAELAGAAGRCNAHSMTGLRPDGAELAEAITAALAAARLNPS
DVDYISGHGSSTKQNDLHETAAYKASLGEHARRTPISSIKSMVGHSLGAIGALEAVACTL
AIEHSVVPPTANLVEPDPECDLDYVPMTAREHRVDVALNVGSGFGGFQSAMVLTAPGRAR
NT seq
1263 nt
NT seq
+upstream
nt +downstream
nt
atggacaggcaggccgtggtgaccgggttgggcgtcgtggcgccgggcgggatcggcgcc
aagcagttctgggagctgctcaccgccggacgcacggcgacccggacgatctcgctgttc
gacgccaccgggttccgctccagggtggccgccgagtgcgacttcgacgcgcgcgtcgcc
gggctgtcccaccggcagatccggatgtgggaccgcaccacccagttcgccgtcgtcgcc
gcgcgggaggcgctggccgacagcggtgtcgccgacggcatcgtccccgagcggaccggc
gtggcgatcgggaccgcgtgcggcatgacgcagagcctcgaccacgagtacgccgtcgcc
agcgacgaggggcgggcctggctggtcgacgaccgccacggctcgccctacctctacgac
tacttcctgccgtcgtccatggccgtcgaggtcgcctggctggtcggggcggaggggccg
gtggcgatcgtgccgaccggctgcacctccggcatcgacgccctggtgcacgcggccgag
ctgatcagggacggcgtggtcgacgtggtggtggcgggcgcgtcggacgcgccgatctcg
ccgatcaccgcggcctgcttcgacgccatcaaggcgaccaccccgcgcaacgacgagccg
gagacggcctcgcgccccttcgaccgcacccgcaacgggttcgccctcgccgagggcgcg
gcggtgctggtgctggaggagggggagcgggcgcggcgccggggcgcgcacgtgtacgcc
gagctggcgggcgcggcgggccgctgcaacgcccacagcatgaccggcctccgccccgac
ggcgccgagctggccgaggcgatcaccgcggcgctcgccgccgcccggctcaatccgtcc
gatgtggactacatcagcgggcacgggtcgtccacgaagcagaatgacctccacgagacc
gccgcgtacaaggcgagcctcggcgagcacgcccgccgcacgccgatcagctcgatcaag
tcgatggtcgggcactccctcggcgcgatcggcgcgctggaggccgtcgcgtgcaccctg
gccatcgagcactcggtcgtgccgcccacggccaacctggtcgagcccgaccccgagtgc
gatctggactacgtgccgatgaccgcgcgcgagcaccgcgtggacgtcgcgctcaacgtc
ggcagcgggttcggcgggttccagagcgcgatggtgctcaccgcgccgggacgggcccgg
tga
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