Actinomadura sp. WMMB 499: F7P10_07035
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Entry
F7P10_07035 CDS
T06213
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
actw
Actinomadura sp. WMMB 499
Pathway
actw00010
Glycolysis / Gluconeogenesis
actw00020
Citrate cycle (TCA cycle)
actw00620
Pyruvate metabolism
actw00785
Lipoic acid metabolism
actw01100
Metabolic pathways
actw01110
Biosynthesis of secondary metabolites
actw01120
Microbial metabolism in diverse environments
actw01200
Carbon metabolism
actw01210
2-Oxocarboxylic acid metabolism
Module
actw_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
actw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
F7P10_07035 (aceE)
00020 Citrate cycle (TCA cycle)
F7P10_07035 (aceE)
00620 Pyruvate metabolism
F7P10_07035 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
F7P10_07035 (aceE)
Enzymes [BR:
actw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
F7P10_07035 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
QFG20931
UniProt:
A0A5J6U4H1
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All DBs
Position
1622189..1624978
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AA seq
929 aa
AA seq
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MASGRQRYSIISDGLPSQLPDINPDETREWLESLDTVIKTEGRGRARYVMLRLLERAREL
QVGVPGLRSTDFLNTIPPELEPWFPGDEHVERRIRAYIRWNAAIMVSRANRPEIGVGGHI
ATYASAASLYEVGFNHFFRGKDHGESGDQVFIQGHASPGIYARAYLEGRLPEEKLDGFRQ
EQSHPGGGLSSYPHPRLMPDFWEFPTVSMGLTAIDAVYQARFNRYLYNRRIKDTSRSHVW
AFLGDGEMGEPESLGAIGLAAREELDNLTFVVNCNLQQLDGPVRGNGKIIQELESYFRGA
GWNVIKVIWGRDWDPLIAQDVDGALVNKMNTTPDGQFQTFSVEAGSYIREKFFGDDPRLR
KIVQHLSDDDLRKLSRGGHDYRKVYAAFKSAREHVGQPTVILAHTVKGWTLGSDFEARNA
THQMKKLTKAELKEFRDRLYLDIPDSALEQPLPPYYHPGEDSDEIQYMRERRAALGGFLP
KRVVRAKPLKLPGDPVYAELKKGSGKQNVATTMAFVRLLKDLIKDENIGARFVPIAPDEY
RTFGMDSLFPTSKIYSPHGQTYDAVDRKLLLSYKESESGQMLHEGISEAGSMASTIAAGT
SYATHGEHMIPVYIFYSMFGFQRTGDQMWALGDQMGRGFLLGATAGRTTLTGEGLQHADG
HSPLIAATNPACVHYDPTWSFELAYITQDALRRMYGTSEQHPDGEDVFYYLTVYNEPYQQ
PAEPDGVDVDGLLKGLYRYKAAPDVASAGGQAPRAQILASGVGGRWALEAQRLLAEDWGV
AADVWSATSWNELAREARECDERNLLDPEGEQRVPYVTRALDNVAGPIVAVSDFARAVPD
QIAPWVDGDFTSLGTDGFGFSDTRAAARRFFHVDSASIVLAVLTRLVRHGEVKPEALPQA
IERYRLNATVGEVFAGGVGSAESNTGGES
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggacgtcaacgctactcgatcatcagcgacggcctgccgagccagctgccc
gacatcaacccggacgaaacccgggagtggctggaatcgctggacacggtcatcaagacc
gagggccgtggccgggcccgctacgtgatgctgcggctcctggaacgtgcccgcgaactg
caggtcggcgtacccggtctgcgcagcaccgacttcctcaacacgatcccgccggagctg
gagccgtggttccccggcgacgagcacgtcgagcgccgcatccgcgcctacatccggtgg
aacgccgcgatcatggtgtcgcgcgcgaaccgtcccgagatcggggtcggcgggcacatc
gccacgtacgcgtcggccgcgtcgctgtacgaggtcgggttcaaccacttcttccgcggc
aaggaccacggcgagtccggcgaccaggtgttcatccaggggcacgcctcccccggcatc
tacgcccgcgcctacctggagggacggctgccggaggagaagctggacggcttccggcag
gagcagtcgcaccccggcggcgggctgtcgtcgtacccgcacccccggctgatgccggac
ttctgggagttccccacggtgtccatgggcctcaccgcgatcgacgcggtgtaccaggcc
cgcttcaaccgctacctgtacaaccgcaggatcaaggacacgtcccgctcgcacgtgtgg
gcgttcctcggcgacggcgagatgggcgagcccgagtcgctcggcgcgatcggcctcgcc
gcccgcgaggagctggacaacctcaccttcgtcgtcaactgcaacctgcagcagctcgac
ggcccggtgcgcggcaacggcaagatcatccaggagctcgagtcgtacttccgcggcgcg
ggctggaacgtcatcaaggtcatctggggccgcgactgggacccgctgatcgcccaggac
gtcgacggcgcgctcgtcaacaagatgaacaccacgcccgacggccagttccagacgttc
agcgtcgaggccggctcgtacatccgggagaagttcttcggcgacgacccccggctgcgc
aagatcgtccagcacctgtcggacgacgacctgcgcaagctgtcgcgcggcgggcacgac
taccggaaggtgtacgcggcgttcaagtcggcccgcgagcacgtcgggcagccgacggtg
atcctcgcgcacacggtcaagggctggacgctcggctccgacttcgaggcccgcaacgcc
acgcaccagatgaagaagctcaccaaggccgagctgaaggagttccgcgaccgcctctac
ctggacatcccggactccgcgctcgagcagccgctgccgccctactaccacccgggcgag
gactccgacgagatccagtacatgcgcgagcgccgggccgcgctcggcgggttcctgccg
aagcgggtcgtgcgggccaagccgctgaagctgcccggcgacccggtctacgcggagctg
aagaaggggtccggcaagcagaacgtggcgacgacgatggcgttcgtccggctgctcaag
gacctcatcaaggacgagaacatcggcgcccggttcgtcccgatcgccccggacgagtac
cgcacgttcggcatggactcgctgttccccacgtccaagatctactcgccgcacgggcag
acctacgacgcggtggaccgcaagctgctgctgtcctacaaggagtccgagagcggccag
atgctgcacgagggcatcagcgaggccggttcgatggcgtcgacgatcgccgcgggcacg
tcctacgccacgcacggcgagcacatgatccccgtctacatcttctactcgatgttcggg
ttccagcggaccggcgaccagatgtgggcgctcggcgaccagatgggccgcgggttcctg
ctcggcgccaccgcgggccgcaccaccctcaccggcgagggcctgcagcacgccgacggc
cactccccgctcatcgcggcgacgaaccccgcgtgcgtccactacgaccccacctggtcg
ttcgagctggcgtacatcacgcaggacgcgctgcgccgcatgtacgggacgtccgagcag
cacccggacggcgaggacgtcttctactacctcaccgtctacaacgagccctaccagcag
cccgccgaacccgacggggtggacgtcgacggcctgctcaagggcctgtaccggtacaag
gccgcaccggacgtcgcctcggccggcgggcaggcgccgcgcgcgcagatcctcgcgtcc
ggcgtcggcggccggtgggccctcgaggcgcagcggctcctcgccgaggactggggcgtc
gccgcggacgtctggtcggcgacctcgtggaacgagctggcccgcgaggcccgcgagtgc
gacgagcgcaacctgctcgaccccgagggcgagcagcgcgtcccgtacgtcacccgcgcc
ctcgacaacgtcgccggaccgatcgtcgcggtgtcggacttcgcccgcgccgtccccgac
cagatcgccccgtgggtggacggcgacttcacctcgctcggcaccgacgggttcggtttc
tccgacacccgggccgccgcccgccggttcttccacgtggactcggcgtcgatcgtcctg
gccgtcctcacccggctcgtccggcacggcgaggtcaagccggaggccctcccgcaggcc
atcgagcggtaccggctgaacgcgacggtcggcgaagtcttcgccggcggcgtcggcagc
gccgagagcaacaccggcggggagagctga
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